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Bivalent mRNA booster encoding virus-like particles elicits potent polyclass RBD antibodies in pre-vaccinated mice.

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Title: Bivalent mRNA booster encoding virus-like particles elicits potent polyclass RBD antibodies in pre-vaccinated mice.
Authors: Fan C; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; These authors contributed equally., Cohen AA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; These authors contributed equally., Dam KA; Gladstone Institutes, San Francisco, CA 94158, USA.; These authors contributed equally., Rorick AV; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; Present address: Department of Biochemistry, University of Washington, Seattle, WA 98109, USA., Priso Fils AI; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Yang Z; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; Present address: Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA., Gnanapragasam PNP; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Segovia LN; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Huey-Tubman KE; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Moon WJ; Acuitas Therapeutics, Vancouver, BC, V6T 1Z3, CANADA., Lin PJC; Acuitas Therapeutics, Vancouver, BC, V6T 1Z3, CANADA., Bjorkman PJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Hoffmann MAG; Gladstone Institutes, San Francisco, CA 94158, USA.; Department of Medicine, University of California, San Francisco, CA 94143, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Aug 19. Date of Electronic Publication: 2025 Aug 19.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Bivalent mRNA booster encoding virus-like particles elicits potent polyclass RBD antibodies in pre-vaccinated mice.
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  Data: <searchLink fieldCode="AU" term="%22Fan+C%22">Fan C</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; These authors contributed equally.<br /><searchLink fieldCode="AU" term="%22Cohen+AA%22">Cohen AA</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; These authors contributed equally.<br /><searchLink fieldCode="AU" term="%22Dam+KA%22">Dam KA</searchLink>; Gladstone Institutes, San Francisco, CA 94158, USA.; These authors contributed equally.<br /><searchLink fieldCode="AU" term="%22Rorick+AV%22">Rorick AV</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; Present address: Department of Biochemistry, University of Washington, Seattle, WA 98109, USA.<br /><searchLink fieldCode="AU" term="%22Priso+Fils+AI%22">Priso Fils AI</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.<br /><searchLink fieldCode="AU" term="%22Yang+Z%22">Yang Z</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.; Present address: Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.<br /><searchLink fieldCode="AU" term="%22Gnanapragasam+PNP%22">Gnanapragasam PNP</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.<br /><searchLink fieldCode="AU" term="%22Segovia+LN%22">Segovia LN</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.<br /><searchLink fieldCode="AU" term="%22Huey-Tubman+KE%22">Huey-Tubman KE</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.<br /><searchLink fieldCode="AU" term="%22Moon+WJ%22">Moon WJ</searchLink>; Acuitas Therapeutics, Vancouver, BC, V6T 1Z3, CANADA.<br /><searchLink fieldCode="AU" term="%22Lin+PJC%22">Lin PJC</searchLink>; Acuitas Therapeutics, Vancouver, BC, V6T 1Z3, CANADA.<br /><searchLink fieldCode="AU" term="%22Bjorkman+PJ%22">Bjorkman PJ</searchLink>; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.<br /><searchLink fieldCode="AU" term="%22Hoffmann+MAG%22">Hoffmann MAG</searchLink>; Gladstone Institutes, San Francisco, CA 94158, USA.; Department of Medicine, University of California, San Francisco, CA 94143, USA.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Aug 19. <i>Date of Electronic Publication: </i>2025 Aug 19.
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