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Early-onset colorectal cancer patients exhibit a distinct molecular fingerprint: insights from a large-scale NGS study of 1209 patients.

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Title: Early-onset colorectal cancer patients exhibit a distinct molecular fingerprint: insights from a large-scale NGS study of 1209 patients.
Authors: Pretta A; Medical Oncology Unit, University Hospital and University of Cagliari, Cagliari, Italy. Electronic address: an.pretta@gmail.com., Nasca V; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Marmorino F; Unit of Oncology, University Hospital of Pisa, Pisa, Italy; Department of Translational Research & New Technologies in Medicine & Surgery, University of Pisa, Pisa, Italy., Intini R; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Ziranu P; Medical Oncology Unit, University Hospital and University of Cagliari, Cagliari, Italy., Randon G; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Carullo M; Unit of Oncology, University Hospital of Pisa, Pisa, Italy; Department of Translational Research & New Technologies in Medicine & Surgery, University of Pisa, Pisa, Italy., Cerma K; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Donisi C; Medical Oncology Unit, University Hospital and University of Cagliari, Cagliari, Italy., Damonte C; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Taravella A; Unit of Oncology, University Hospital of Pisa, Pisa, Italy; Department of Translational Research & New Technologies in Medicine & Surgery, University of Pisa, Pisa, Italy., Gaiani C; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy; Department of Surgery, Oncology, and Gastroenterology, University of Padua, Padua, Italy., Pretta G; Science Department, King's School Hove, Hangleton, UK., Pusceddu V; Medical Oncology Unit, University Hospital and University of Cagliari, Cagliari, Italy., Montroni I; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Ciracì P; Unit of Oncology, University Hospital of Pisa, Pisa, Italy; Department of Translational Research & New Technologies in Medicine & Surgery, University of Pisa, Pisa, Italy., De Rosa A; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy; Department of Surgery, Oncology, and Gastroenterology, University of Padua, Padua, Italy., Bergamo F; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Lonardi S; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Cremolini C; Unit of Oncology, University Hospital of Pisa, Pisa, Italy; Department of Translational Research & New Technologies in Medicine & Surgery, University of Pisa, Pisa, Italy., Pietrantonio F; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Scartozzi M; Medical Oncology Unit, University Hospital and University of Cagliari, Cagliari, Italy.
Source: ESMO open [ESMO Open] 2025 Sep; Vol. 10 (9), pp. 105756. Date of Electronic Publication: 2025 Sep 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101690685 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2059-7029 (Electronic) Linking ISSN: 20597029 NLM ISO Abbreviation: ESMO Open Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Early-onset colorectal cancer patients exhibit a distinct molecular fingerprint: insights from a large-scale NGS study of 1209 patients.
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  Data: <searchLink fieldCode="AU" term="%22Pretta+A%22">Pretta A</searchLink>; Medical Oncology Unit, University Hospital and University of Cagliari, Cagliari, Italy. Electronic address: an.pretta@gmail.com.<br /><searchLink fieldCode="AU" term="%22Nasca+V%22">Nasca V</searchLink>; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Marmorino+F%22">Marmorino F</searchLink>; Unit of Oncology, University Hospital of Pisa, Pisa, Italy; Department of Translational Research & New Technologies in Medicine & Surgery, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Intini+R%22">Intini R</searchLink>; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Ziranu+P%22">Ziranu P</searchLink>; Medical Oncology Unit, University Hospital and University of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Randon+G%22">Randon G</searchLink>; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Carullo+M%22">Carullo M</searchLink>; Unit of Oncology, University Hospital of Pisa, Pisa, Italy; Department of Translational Research & New Technologies in Medicine & Surgery, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Cerma+K%22">Cerma K</searchLink>; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Donisi+C%22">Donisi C</searchLink>; Medical Oncology Unit, University Hospital and University of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Damonte+C%22">Damonte C</searchLink>; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Taravella+A%22">Taravella A</searchLink>; Unit of Oncology, University Hospital of Pisa, Pisa, Italy; Department of Translational Research & New Technologies in Medicine & Surgery, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Gaiani+C%22">Gaiani C</searchLink>; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy; Department of Surgery, Oncology, and Gastroenterology, University of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Pretta+G%22">Pretta G</searchLink>; Science Department, King's School Hove, Hangleton, UK.<br /><searchLink fieldCode="AU" term="%22Pusceddu+V%22">Pusceddu V</searchLink>; Medical Oncology Unit, University Hospital and University of Cagliari, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Montroni+I%22">Montroni I</searchLink>; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ciracì+P%22">Ciracì P</searchLink>; Unit of Oncology, University Hospital of Pisa, Pisa, Italy; Department of Translational Research & New Technologies in Medicine & Surgery, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22De+Rosa+A%22">De Rosa A</searchLink>; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy; Department of Surgery, Oncology, and Gastroenterology, University of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Bergamo+F%22">Bergamo F</searchLink>; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Lonardi+S%22">Lonardi S</searchLink>; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Cremolini+C%22">Cremolini C</searchLink>; Unit of Oncology, University Hospital of Pisa, Pisa, Italy; Department of Translational Research & New Technologies in Medicine & Surgery, University of Pisa, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Pietrantonio+F%22">Pietrantonio F</searchLink>; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Scartozzi+M%22">Scartozzi M</searchLink>; Medical Oncology Unit, University Hospital and University of Cagliari, Cagliari, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101690685%22">ESMO open</searchLink> [ESMO Open] 2025 Sep; Vol. 10 (9), pp. 105756. <i>Date of Electronic Publication: </i>2025 Sep 01.
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