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Early-onset colorectal cancer patients exhibit a distinct molecular fingerprint: insights from a large-scale NGS study of 1209 patients.

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Title: Early-onset colorectal cancer patients exhibit a distinct molecular fingerprint: insights from a large-scale NGS study of 1209 patients.
Authors: Pretta A; Medical Oncology Unit, University Hospital and University of Cagliari, Cagliari, Italy. Electronic address: an.pretta@gmail.com., Nasca V; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Marmorino F; Unit of Oncology, University Hospital of Pisa, Pisa, Italy; Department of Translational Research & New Technologies in Medicine & Surgery, University of Pisa, Pisa, Italy., Intini R; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Ziranu P; Medical Oncology Unit, University Hospital and University of Cagliari, Cagliari, Italy., Randon G; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Carullo M; Unit of Oncology, University Hospital of Pisa, Pisa, Italy; Department of Translational Research & New Technologies in Medicine & Surgery, University of Pisa, Pisa, Italy., Cerma K; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Donisi C; Medical Oncology Unit, University Hospital and University of Cagliari, Cagliari, Italy., Damonte C; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Taravella A; Unit of Oncology, University Hospital of Pisa, Pisa, Italy; Department of Translational Research & New Technologies in Medicine & Surgery, University of Pisa, Pisa, Italy., Gaiani C; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy; Department of Surgery, Oncology, and Gastroenterology, University of Padua, Padua, Italy., Pretta G; Science Department, King's School Hove, Hangleton, UK., Pusceddu V; Medical Oncology Unit, University Hospital and University of Cagliari, Cagliari, Italy., Montroni I; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Ciracì P; Unit of Oncology, University Hospital of Pisa, Pisa, Italy; Department of Translational Research & New Technologies in Medicine & Surgery, University of Pisa, Pisa, Italy., De Rosa A; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy; Department of Surgery, Oncology, and Gastroenterology, University of Padua, Padua, Italy., Bergamo F; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Lonardi S; Oncology Unit 1, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy., Cremolini C; Unit of Oncology, University Hospital of Pisa, Pisa, Italy; Department of Translational Research & New Technologies in Medicine & Surgery, University of Pisa, Pisa, Italy., Pietrantonio F; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Scartozzi M; Medical Oncology Unit, University Hospital and University of Cagliari, Cagliari, Italy.
Source: ESMO open [ESMO Open] 2025 Sep; Vol. 10 (9), pp. 105756. Date of Electronic Publication: 2025 Sep 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101690685 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2059-7029 (Electronic) Linking ISSN: 20597029 NLM ISO Abbreviation: ESMO Open Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2059-7029
DOI:10.1016/j.esmoop.2025.105756