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Influence of Sex and Diagnosis on Clinical Variables and Neurocognitive Performance in Severe Mental Illness. Results From the PsyCourse Study.

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Title: Influence of Sex and Diagnosis on Clinical Variables and Neurocognitive Performance in Severe Mental Illness. Results From the PsyCourse Study.
Authors: Serra-Navarro M; Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Hospital Clinic of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Fundació Clínic per la Recerca Biomèdica-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FCRB-IDIBAPS), Barcelona, Spain.; Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociencies (UBNeuro), Universitat de Barcelona (UB), Barcelona, Spain., Heilbronner M; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany., Solé B; Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Hospital Clinic of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Fundació Clínic per la Recerca Biomèdica-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FCRB-IDIBAPS), Barcelona, Spain., Borràs R; Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Hospital Clinic of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Fundació Clínic per la Recerca Biomèdica-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FCRB-IDIBAPS), Barcelona, Spain., Martinez-Arán A; Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Hospital Clinic of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Fundació Clínic per la Recerca Biomèdica-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FCRB-IDIBAPS), Barcelona, Spain.; Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociencies (UBNeuro), Universitat de Barcelona (UB), Barcelona, Spain., Adorjan K; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.; University Hospital of Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland., Navarro-Flores A; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.; International Max Planck Research School for Translational Psychiatry (IMPRS-TP), Munich, Germany., Oraki Kohshour M; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.; Department of Immunology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran., Reich-Erkelenz D; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany., Schulte EC; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Bonn, University of Bonn, Bonn, Germany.; Institute of Human Genetics, University Hospital, Faculty of Medicine, University of Bonn, Bonn, Germany.; German Center for Mental Health (DZPG), Partner Site Munich/Augsburg, Munich/Augsburg, Germany., Senner F; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany.; Centres for Psychiatry Suedwuerttemberg, Ravensburg, Germany., Anghelescu IG; Department of Psychiatry and Psychotherapy, Mental Health Institute Berlin, Berlin, Germany., Arolt V; Institute for Translational Psychiatry, University of Münster, Münster, Germany., Baune BT; Department of Psychiatry, University of Melbourne and the Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia.; Department of Psychiatry, University of Münster, Münster, Germany., Dannlowski U; Institute for Translational Psychiatry, University of Münster, Münster, Germany., Dietrich DE; AMEOS Clinical Center Hildesheim, Hildesheim, Germany.; Center for Systems Neuroscience (ZSN), Hannover, Germany.; Department of Psychiatry, Medical School of Hannover, Hannover, Germany., Fallgatter AJ; Department of Psychiatry and Psychotherapy, Tübingen Center for Mental Health (TüCMH), University of Tübingen, Tübingen, Germany.; German Center for Mental Health (DZPG), Partner Site Tübingen, Tübingen, Germany., Figge C; Karl-Jaspers Clinic, European Medical School Oldenburg-Groningen, Oldenburg, Germany., Jäger M; Department of Psychiatry II, Ulm University, Bezirkskrankenhaus Günzburg, Günzburg, Germany., Juckel G; Department of Psychiatry, Ruhr University Bochum, LWL University Hospital, Bochum, Germany., Konrad C; Department of Psychiatry and Psychotherapy, Agaplesion Diakonieklinikum, Rotenburg, Germany., Reimer J; Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Center for Psychosocial Medicine, Academic Teaching Hospital Itzehoe, Itzehoe, Germany., Reininghaus EZ; Division of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, Austria., Schmauß M; Clinic for Psychiatry, Psychotherapy and Psychosomatics, Augsburg University, Medical Faculty, Bezirkskrankenhaus Augsburg, Augsburg, Germany., Schmitt A; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany.; Laboratory of Neuroscience (LIM27), Institute of Psychiatry, University of Sao Paulo, São Paulo, Brazil.; Max Planck Institute of Psychiatry, Munich, Germany., Spitzer C; Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Rostock, Rostock, Germany., Wiltfang J; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany.; Neurosciences and Signaling Group, Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, Aveiro, Portugal., Zimmermann J; Psychiatrieverbund Oldenburger Land gGmbH, Karl-Jaspers-Klinik, Bad Zwischenahn, Germany., Papiol S; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.; Max Planck Institute of Psychiatry, Munich, Germany., Heilbronner U; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany., Falkai P; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany.; German Center for Mental Health (DZPG), Partner Site Munich/Augsburg, Munich/Augsburg, Germany.; Max Planck Institute of Psychiatry, Munich, Germany., Schulze TG; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.; German Center for Mental Health (DZPG), Partner Site Munich/Augsburg, Munich/Augsburg, Germany.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, New York, USA., Vieta E; Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Hospital Clinic of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Fundació Clínic per la Recerca Biomèdica-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FCRB-IDIBAPS), Barcelona, Spain.; Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociencies (UBNeuro), Universitat de Barcelona (UB), Barcelona, Spain., Torrent C; Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Hospital Clinic of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Fundació Clínic per la Recerca Biomèdica-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FCRB-IDIBAPS), Barcelona, Spain., Budde M; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany., Amoretti S; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Group of Psychiatry, Mental Health and Addictions, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.
Source: Acta psychiatrica Scandinavica [Acta Psychiatr Scand] 2026 May; Vol. 153 (5), pp. 449-467. Date of Electronic Publication: 2025 Sep 03.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 0370364 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0447 (Electronic) Linking ISSN: 0001690X NLM ISO Abbreviation: Acta Psychiatr Scand Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Influence of Sex and Diagnosis on Clinical Variables and Neurocognitive Performance in Severe Mental Illness. Results From the PsyCourse Study.
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  Data: <searchLink fieldCode="AU" term="%22Serra-Navarro+M%22">Serra-Navarro M</searchLink>; Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Hospital Clinic of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Fundació Clínic per la Recerca Biomèdica-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FCRB-IDIBAPS), Barcelona, Spain.; Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociencies (UBNeuro), Universitat de Barcelona (UB), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Heilbronner+M%22">Heilbronner M</searchLink>; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Solé+B%22">Solé B</searchLink>; Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Hospital Clinic of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Fundació Clínic per la Recerca Biomèdica-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FCRB-IDIBAPS), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Borràs+R%22">Borràs R</searchLink>; Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Hospital Clinic of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Fundació Clínic per la Recerca Biomèdica-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FCRB-IDIBAPS), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Martinez-Arán+A%22">Martinez-Arán A</searchLink>; Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Hospital Clinic of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Fundació Clínic per la Recerca Biomèdica-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FCRB-IDIBAPS), Barcelona, Spain.; Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociencies (UBNeuro), Universitat de Barcelona (UB), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Adorjan+K%22">Adorjan K</searchLink>; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.; University Hospital of Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Navarro-Flores+A%22">Navarro-Flores A</searchLink>; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.; International Max Planck Research School for Translational Psychiatry (IMPRS-TP), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Oraki+Kohshour+M%22">Oraki Kohshour M</searchLink>; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.; Department of Immunology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.<br /><searchLink fieldCode="AU" term="%22Reich-Erkelenz+D%22">Reich-Erkelenz D</searchLink>; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schulte+EC%22">Schulte EC</searchLink>; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Bonn, University of Bonn, Bonn, Germany.; Institute of Human Genetics, University Hospital, Faculty of Medicine, University of Bonn, Bonn, Germany.; German Center for Mental Health (DZPG), Partner Site Munich/Augsburg, Munich/Augsburg, Germany.<br /><searchLink fieldCode="AU" term="%22Senner+F%22">Senner F</searchLink>; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany.; Centres for Psychiatry Suedwuerttemberg, Ravensburg, Germany.<br /><searchLink fieldCode="AU" term="%22Anghelescu+IG%22">Anghelescu IG</searchLink>; Department of Psychiatry and Psychotherapy, Mental Health Institute Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Arolt+V%22">Arolt V</searchLink>; Institute for Translational Psychiatry, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Baune+BT%22">Baune BT</searchLink>; Department of Psychiatry, University of Melbourne and the Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Australia.; Department of Psychiatry, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Dannlowski+U%22">Dannlowski U</searchLink>; Institute for Translational Psychiatry, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Dietrich+DE%22">Dietrich DE</searchLink>; AMEOS Clinical Center Hildesheim, Hildesheim, Germany.; Center for Systems Neuroscience (ZSN), Hannover, Germany.; Department of Psychiatry, Medical School of Hannover, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Fallgatter+AJ%22">Fallgatter AJ</searchLink>; Department of Psychiatry and Psychotherapy, Tübingen Center for Mental Health (TüCMH), University of Tübingen, Tübingen, Germany.; German Center for Mental Health (DZPG), Partner Site Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Figge+C%22">Figge C</searchLink>; Karl-Jaspers Clinic, European Medical School Oldenburg-Groningen, Oldenburg, Germany.<br /><searchLink fieldCode="AU" term="%22Jäger+M%22">Jäger M</searchLink>; Department of Psychiatry II, Ulm University, Bezirkskrankenhaus Günzburg, Günzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Juckel+G%22">Juckel G</searchLink>; Department of Psychiatry, Ruhr University Bochum, LWL University Hospital, Bochum, Germany.<br /><searchLink fieldCode="AU" term="%22Konrad+C%22">Konrad C</searchLink>; Department of Psychiatry and Psychotherapy, Agaplesion Diakonieklinikum, Rotenburg, Germany.<br /><searchLink fieldCode="AU" term="%22Reimer+J%22">Reimer J</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Center for Psychosocial Medicine, Academic Teaching Hospital Itzehoe, Itzehoe, Germany.<br /><searchLink fieldCode="AU" term="%22Reininghaus+EZ%22">Reininghaus EZ</searchLink>; Division of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, Austria.<br /><searchLink fieldCode="AU" term="%22Schmauß+M%22">Schmauß M</searchLink>; Clinic for Psychiatry, Psychotherapy and Psychosomatics, Augsburg University, Medical Faculty, Bezirkskrankenhaus Augsburg, Augsburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schmitt+A%22">Schmitt A</searchLink>; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany.; Laboratory of Neuroscience (LIM27), Institute of Psychiatry, University of Sao Paulo, São Paulo, Brazil.; Max Planck Institute of Psychiatry, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Spitzer+C%22">Spitzer C</searchLink>; Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Rostock, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Wiltfang+J%22">Wiltfang J</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany.; Neurosciences and Signaling Group, Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, Aveiro, Portugal.<br /><searchLink fieldCode="AU" term="%22Zimmermann+J%22">Zimmermann J</searchLink>; Psychiatrieverbund Oldenburger Land gGmbH, Karl-Jaspers-Klinik, Bad Zwischenahn, Germany.<br /><searchLink fieldCode="AU" term="%22Papiol+S%22">Papiol S</searchLink>; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.; Max Planck Institute of Psychiatry, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Heilbronner+U%22">Heilbronner U</searchLink>; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Falkai+P%22">Falkai P</searchLink>; Department of Psychiatry and Psychotherapy, LMU University Hospital, LMU Munich, Munich, Germany.; German Center for Mental Health (DZPG), Partner Site Munich/Augsburg, Munich/Augsburg, Germany.; Max Planck Institute of Psychiatry, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schulze+TG%22">Schulze TG</searchLink>; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.; German Center for Mental Health (DZPG), Partner Site Munich/Augsburg, Munich/Augsburg, Germany.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Psychiatry and Behavioral Sciences, SUNY Upstate Medical University, Syracuse, New York, USA.<br /><searchLink fieldCode="AU" term="%22Vieta+E%22">Vieta E</searchLink>; Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Hospital Clinic of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Fundació Clínic per la Recerca Biomèdica-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FCRB-IDIBAPS), Barcelona, Spain.; Departament de Medicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociencies (UBNeuro), Universitat de Barcelona (UB), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Torrent+C%22">Torrent C</searchLink>; Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Hospital Clinic of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Fundació Clínic per la Recerca Biomèdica-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FCRB-IDIBAPS), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Budde+M%22">Budde M</searchLink>; Institute of Psychiatric Phenomics and Genomics (IPPG), LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Amoretti+S%22">Amoretti S</searchLink>; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Group of Psychiatry, Mental Health and Addictions, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.
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  Data: <searchLink fieldCode="JN" term="%220370364%22">Acta psychiatrica Scandinavica</searchLink> [Acta Psychiatr Scand] 2026 May; Vol. 153 (5), pp. 449-467. <i>Date of Electronic Publication: </i>2025 Sep 03.
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      – BibEntity:
          Dates:
            – D: 01
              M: 05
              Text: 2026 May
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1600-0447
          Numbering:
            – Type: volume
              Value: 153
            – Type: issue
              Value: 5
          Titles:
            – TitleFull: Acta psychiatrica Scandinavica
              Type: main
ResultId 1