Translational investigations in the HN1901 phase II window-of-opportunity study investigating the biological activity of an IDO1 (IO102) and PD-L1 (IO103) immune-modulatory peptide cancer vaccines in squamous cell carcinoma of the head and neck.
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| Title: | Translational investigations in the HN1901 phase II window-of-opportunity study investigating the biological activity of an IDO1 (IO102) and PD-L1 (IO103) immune-modulatory peptide cancer vaccines in squamous cell carcinoma of the head and neck. |
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| Authors: | Beyaert S; Institut de Recherche Expérimentale et Clinique (IREC), pôle MIRO, Université catholique de Louvain (UCLouvain), Brussels, Belgium. simon.beyaert@saintluc.uclouvain.be., Loriot A; Group of Computational Biology and Bioinformatics, de Duve Institute, Université catholique de Louvain, Brussels, Belgium., Magremanne M; Department of Oral and Maxillofacial surgery, Institut Roi Albert II & Cliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium., Renwart W; Department of Head & Neck Surgery, Institut Roi Albert II & Cliniques universitaires Saint-Luc, Brussels, Belgium., Mahy P; Department of Oral and Maxillofacial surgery, Institut Roi Albert II & Cliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium., Duprez T; Department of Radiology, Institut Roi Albert II & Cliniques universitaires Saint-Luc, Brussels, Belgium., Baldin P; Department of Pathology, Cliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium., Benidovskaya E; Institut de Recherche Expérimentale et Clinique (IREC), pôle MIRO, Université catholique de Louvain (UCLouvain), Brussels, Belgium., Huyghe N; Institut de Recherche Expérimentale et Clinique (IREC), pôle MIRO, Université catholique de Louvain (UCLouvain), Brussels, Belgium., Dahou H; Institut de Recherche Expérimentale et Clinique (IREC), pôle MIRO, Université catholique de Louvain (UCLouvain), Brussels, Belgium., Stroobant V; de Duve Institute, Ludwig Institute for Cancer Research, Brussels, Belgium., Gomard T; de Duve Institute, Ludwig Institute for Cancer Research, Brussels, Belgium., Machiels JP; Institut de Recherche Expérimentale et Clinique (IREC), pôle MIRO, Université catholique de Louvain (UCLouvain), Brussels, Belgium.; Department of Medical Oncology, Institut Roi Albert II & Cliniques universitaires Saint- Luc, Brussels, Belgium., Schmitz S; Institut de Recherche Expérimentale et Clinique (IREC), pôle MIRO, Université catholique de Louvain (UCLouvain), Brussels, Belgium.; Department of Head & Neck Surgery, Institut Roi Albert II & Cliniques universitaires Saint-Luc, Brussels, Belgium. |
| Source: | European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery [Eur Arch Otorhinolaryngol] 2025 Nov; Vol. 282 (11), pp. 5841-5855. Date of Electronic Publication: 2025 Sep 03. |
| Publication Type: | Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial |
| Journal Info: | Publisher: Springer International Country of Publication: Germany NLM ID: 9002937 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1434-4726 (Electronic) Linking ISSN: 09374477 NLM ISO Abbreviation: Eur Arch Otorhinolaryngol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40900323 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Translational investigations in the HN1901 phase II window-of-opportunity study investigating the biological activity of an IDO1 (IO102) and PD-L1 (IO103) immune-modulatory peptide cancer vaccines in squamous cell carcinoma of the head and neck. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Beyaert+S%22">Beyaert S</searchLink>; Institut de Recherche Expérimentale et Clinique (IREC), pôle MIRO, Université catholique de Louvain (UCLouvain), Brussels, Belgium. simon.beyaert@saintluc.uclouvain.be.<br /><searchLink fieldCode="AU" term="%22Loriot+A%22">Loriot A</searchLink>; Group of Computational Biology and Bioinformatics, de Duve Institute, Université catholique de Louvain, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Magremanne+M%22">Magremanne M</searchLink>; Department of Oral and Maxillofacial surgery, Institut Roi Albert II & Cliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Renwart+W%22">Renwart W</searchLink>; Department of Head & Neck Surgery, Institut Roi Albert II & Cliniques universitaires Saint-Luc, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Mahy+P%22">Mahy P</searchLink>; Department of Oral and Maxillofacial surgery, Institut Roi Albert II & Cliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Duprez+T%22">Duprez T</searchLink>; Department of Radiology, Institut Roi Albert II & Cliniques universitaires Saint-Luc, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Baldin+P%22">Baldin P</searchLink>; Department of Pathology, Cliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Benidovskaya+E%22">Benidovskaya E</searchLink>; Institut de Recherche Expérimentale et Clinique (IREC), pôle MIRO, Université catholique de Louvain (UCLouvain), Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Huyghe+N%22">Huyghe N</searchLink>; Institut de Recherche Expérimentale et Clinique (IREC), pôle MIRO, Université catholique de Louvain (UCLouvain), Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Dahou+H%22">Dahou H</searchLink>; Institut de Recherche Expérimentale et Clinique (IREC), pôle MIRO, Université catholique de Louvain (UCLouvain), Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Stroobant+V%22">Stroobant V</searchLink>; de Duve Institute, Ludwig Institute for Cancer Research, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Gomard+T%22">Gomard T</searchLink>; de Duve Institute, Ludwig Institute for Cancer Research, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Machiels+JP%22">Machiels JP</searchLink>; Institut de Recherche Expérimentale et Clinique (IREC), pôle MIRO, Université catholique de Louvain (UCLouvain), Brussels, Belgium.; Department of Medical Oncology, Institut Roi Albert II & Cliniques universitaires Saint- Luc, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Schmitz+S%22">Schmitz S</searchLink>; Institut de Recherche Expérimentale et Clinique (IREC), pôle MIRO, Université catholique de Louvain (UCLouvain), Brussels, Belgium.; Department of Head & Neck Surgery, Institut Roi Albert II & Cliniques universitaires Saint-Luc, Brussels, Belgium. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229002937%22">European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery</searchLink> [Eur Arch Otorhinolaryngol] 2025 Nov; Vol. 282 (11), pp. 5841-5855. <i>Date of Electronic Publication: </i>2025 Sep 03. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International%22">Springer International </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>9002937 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1434-4726 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209374477%22">09374477 </searchLink><i>NLM ISO Abbreviation: </i>Eur Arch Otorhinolaryngol <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00405-025-09655-8 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 5841 Titles: – TitleFull: Translational investigations in the HN1901 phase II window-of-opportunity study investigating the biological activity of an IDO1 (IO102) and PD-L1 (IO103) immune-modulatory peptide cancer vaccines in squamous cell carcinoma of the head and neck. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Beyaert S – PersonEntity: Name: NameFull: Loriot A – PersonEntity: Name: NameFull: Magremanne M – PersonEntity: Name: NameFull: Renwart W – PersonEntity: Name: NameFull: Mahy P – PersonEntity: Name: NameFull: Duprez T – PersonEntity: Name: NameFull: Baldin P – PersonEntity: Name: NameFull: Benidovskaya E – PersonEntity: Name: NameFull: Huyghe N – PersonEntity: Name: NameFull: Dahou H – PersonEntity: Name: NameFull: Stroobant V – PersonEntity: Name: NameFull: Gomard T – PersonEntity: Name: NameFull: Machiels JP – PersonEntity: Name: NameFull: Schmitz S IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 11 Text: 2025 Nov Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1434-4726 Numbering: – Type: volume Value: 282 – Type: issue Value: 11 Titles: – TitleFull: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery Type: main |
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