Identifying care gaps along the HIV treatment failure cascade: A multistate analysis of viral load monitoring, re-suppression, and regimen switches in Zambia.

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Title: Identifying care gaps along the HIV treatment failure cascade: A multistate analysis of viral load monitoring, re-suppression, and regimen switches in Zambia.
Authors: Sikombe K; Implementation Science Unit, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia.; Department of Public Health Environments and Society, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom., Le Tourneau N; Division of Infectious Diseases, Washington University School of Medicine, St Louis, Missouri, United States of America., Rice B; Department of Public Health Environments and Society, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom.; Sheffield Centre for Health and Related Research (SCHARR), School of Medicine and Population Health, University of Sheffield, Sheffield, United Kingdom., Pry JM; Implementation Science Unit, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia.; Department of Public Health Sciences, School of Medicine, University of California, Davis, California, United States of America., Simbeza S; Implementation Science Unit, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia., Beres LK; Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America., Sharma A; Implementation Science Unit, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia., Mukamba N; Implementation Science Unit, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia., Wringe A; Department of Public Health Environments and Society, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom., Hargreaves JR; Department of Public Health Environments and Society, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom., Mutale J; Implementation Science Unit, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia., Moore CB; Implementation Science Unit, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia.; Division of Infectious Diseases, University of Alabama, Birmingham, Alabama, United States of America., Sikazwe I; Implementation Science Unit, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia., Geng E; Division of Infectious Diseases, Washington University School of Medicine, St Louis, Missouri, United States of America., Mody A; Division of Infectious Diseases, Washington University School of Medicine, St Louis, Missouri, United States of America.
Source: PLoS medicine [PLoS Med] 2025 Sep 03; Vol. 22 (9), pp. e1004720. Date of Electronic Publication: 2025 Sep 03 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101231360 Publication Model: eCollection Cited Medium: Internet ISSN: 1549-1676 (Electronic) Linking ISSN: 15491277 NLM ISO Abbreviation: PLoS Med Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Sikombe+K%22">Sikombe K</searchLink>; Implementation Science Unit, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia.; Department of Public Health Environments and Society, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Le+Tourneau+N%22">Le Tourneau N</searchLink>; Division of Infectious Diseases, Washington University School of Medicine, St Louis, Missouri, United States of America.<br /><searchLink fieldCode="AU" term="%22Rice+B%22">Rice B</searchLink>; Department of Public Health Environments and Society, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom.; Sheffield Centre for Health and Related Research (SCHARR), School of Medicine and Population Health, University of Sheffield, Sheffield, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Pry+JM%22">Pry JM</searchLink>; Implementation Science Unit, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia.; Department of Public Health Sciences, School of Medicine, University of California, Davis, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Simbeza+S%22">Simbeza S</searchLink>; Implementation Science Unit, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia.<br /><searchLink fieldCode="AU" term="%22Beres+LK%22">Beres LK</searchLink>; Department of International Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, United States of America.<br /><searchLink fieldCode="AU" term="%22Sharma+A%22">Sharma A</searchLink>; Implementation Science Unit, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia.<br /><searchLink fieldCode="AU" term="%22Mukamba+N%22">Mukamba N</searchLink>; Implementation Science Unit, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia.<br /><searchLink fieldCode="AU" term="%22Wringe+A%22">Wringe A</searchLink>; Department of Public Health Environments and Society, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hargreaves+JR%22">Hargreaves JR</searchLink>; Department of Public Health Environments and Society, Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mutale+J%22">Mutale J</searchLink>; Implementation Science Unit, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia.<br /><searchLink fieldCode="AU" term="%22Moore+CB%22">Moore CB</searchLink>; Implementation Science Unit, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia.; Division of Infectious Diseases, University of Alabama, Birmingham, Alabama, United States of America.<br /><searchLink fieldCode="AU" term="%22Sikazwe+I%22">Sikazwe I</searchLink>; Implementation Science Unit, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia.<br /><searchLink fieldCode="AU" term="%22Geng+E%22">Geng E</searchLink>; Division of Infectious Diseases, Washington University School of Medicine, St Louis, Missouri, United States of America.<br /><searchLink fieldCode="AU" term="%22Mody+A%22">Mody A</searchLink>; Division of Infectious Diseases, Washington University School of Medicine, St Louis, Missouri, United States of America.
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