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Immediate versus staged complete revascularisation during index admission in patients with ST-segment elevation myocardial infarction and multivessel disease (OPTION-STEMI): a multicentre, non-inferiority, open-label, randomised trial.

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Title: Immediate versus staged complete revascularisation during index admission in patients with ST-segment elevation myocardial infarction and multivessel disease (OPTION-STEMI): a multicentre, non-inferiority, open-label, randomised trial.
Authors: Kim MC; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea., Ahn JH; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea., Hyun DY; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea., Lim Y; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea., Cho KH; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea., Lee SH; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea., Park S; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea., Oh S; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea., Sim DS; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea., Hong YJ; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea., Kim JH; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea., Jeong MH; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea; Division of Cardiology, Department of Internal Medicine, Gwangju Veterans Hospital, Gwangju, South Korea., Cho JH; St Carollo General Hospital, Suncheon, South Korea., Lee SR; Division of Cardiology, Department of Internal Medicine, Jeonbuk National University Hospital, Jeonbuk National University Medical School, Jeonju, South Korea., Kang DO; Cardiovascular Center, Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, South Korea., Hwang JY; Division of Cardiology, Department of Internal Medicine, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, South Korea., Youn YJ; Division of Cardiology, Department of Internal Medicine, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, South Korea., Lee JH; Division of Cardiology, Department of Internal Medicine, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, South Korea; Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, South Korea., Jeong YH; Chung-Ang University Thrombosis and Biomarker Center, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, South Korea; Division of Cardiology, Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, South Korea; Division of Cardiology, Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine, Changwon, South Korea., Ahn JH; Division of Cardiology, Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine, Changwon, South Korea., Kim DB; Division of Cardiology, Department of Internal Medicine, Bucheon St Mary's Hospital, The Catholic University of Korea, Bucheon, South Korea., Choo EH; Division of Cardiology, Department of Internal Medicine, Seoul St Mary's Hospital, The Catholic University of Korea, Seoul, South Korea., Kim CJ; Division of Cardiology, Department of Internal Medicine, Uijeongbu St Mary's Hospital, The Catholic University of Korea, Uijeongbu, South Korea., Kim W; Division of Cardiology, Department of Internal Medicine, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea., Rhew JY; Presbyterian Medical Center, Jeonju, South Korea., Park JI; Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, South Korea., Yoo SY; Division of Cardiology, Department of Internal Medicine, Good Morning Hospital, Pyeongtaek, South Korea; Division of Cardiology, Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, South Korea., Ahn Y; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea. Electronic address: cecilyk@jnu.ac.kr.
Corporate Authors: OPTION–STEMI Investigators
Source: Lancet (London, England) [Lancet] 2025 Sep 06; Vol. 406 (10507), pp. 1032-1043. Date of Electronic Publication: 2025 Aug 31.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Equivalence Trial; Comparative Study
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-547X (Electronic) Linking ISSN: 01406736 NLM ISO Abbreviation: Lancet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Immediate versus staged complete revascularisation during index admission in patients with ST-segment elevation myocardial infarction and multivessel disease (OPTION-STEMI): a multicentre, non-inferiority, open-label, randomised trial.
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  Data: <searchLink fieldCode="AU" term="%22Kim+MC%22">Kim MC</searchLink>; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+JH%22">Ahn JH</searchLink>; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea.<br /><searchLink fieldCode="AU" term="%22Hyun+DY%22">Hyun DY</searchLink>; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea.<br /><searchLink fieldCode="AU" term="%22Lim+Y%22">Lim Y</searchLink>; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea.<br /><searchLink fieldCode="AU" term="%22Cho+KH%22">Cho KH</searchLink>; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SH%22">Lee SH</searchLink>; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea.<br /><searchLink fieldCode="AU" term="%22Park+S%22">Park S</searchLink>; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea.<br /><searchLink fieldCode="AU" term="%22Oh+S%22">Oh S</searchLink>; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea.<br /><searchLink fieldCode="AU" term="%22Sim+DS%22">Sim DS</searchLink>; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea.<br /><searchLink fieldCode="AU" term="%22Hong+YJ%22">Hong YJ</searchLink>; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JH%22">Kim JH</searchLink>; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea.<br /><searchLink fieldCode="AU" term="%22Jeong+MH%22">Jeong MH</searchLink>; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea; Division of Cardiology, Department of Internal Medicine, Gwangju Veterans Hospital, Gwangju, South Korea.<br /><searchLink fieldCode="AU" term="%22Cho+JH%22">Cho JH</searchLink>; St Carollo General Hospital, Suncheon, South Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SR%22">Lee SR</searchLink>; Division of Cardiology, Department of Internal Medicine, Jeonbuk National University Hospital, Jeonbuk National University Medical School, Jeonju, South Korea.<br /><searchLink fieldCode="AU" term="%22Kang+DO%22">Kang DO</searchLink>; Cardiovascular Center, Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Hwang+JY%22">Hwang JY</searchLink>; Division of Cardiology, Department of Internal Medicine, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, South Korea.<br /><searchLink fieldCode="AU" term="%22Youn+YJ%22">Youn YJ</searchLink>; Division of Cardiology, Department of Internal Medicine, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, South Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JH%22">Lee JH</searchLink>; Division of Cardiology, Department of Internal Medicine, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, South Korea; Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, South Korea.<br /><searchLink fieldCode="AU" term="%22Jeong+YH%22">Jeong YH</searchLink>; Chung-Ang University Thrombosis and Biomarker Center, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, South Korea; Division of Cardiology, Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, South Korea; Division of Cardiology, Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine, Changwon, South Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+JH%22">Ahn JH</searchLink>; Division of Cardiology, Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine, Changwon, South Korea.<br /><searchLink fieldCode="AU" term="%22Kim+DB%22">Kim DB</searchLink>; Division of Cardiology, Department of Internal Medicine, Bucheon St Mary's Hospital, The Catholic University of Korea, Bucheon, South Korea.<br /><searchLink fieldCode="AU" term="%22Choo+EH%22">Choo EH</searchLink>; Division of Cardiology, Department of Internal Medicine, Seoul St Mary's Hospital, The Catholic University of Korea, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Kim+CJ%22">Kim CJ</searchLink>; Division of Cardiology, Department of Internal Medicine, Uijeongbu St Mary's Hospital, The Catholic University of Korea, Uijeongbu, South Korea.<br /><searchLink fieldCode="AU" term="%22Kim+W%22">Kim W</searchLink>; Division of Cardiology, Department of Internal Medicine, Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Rhew+JY%22">Rhew JY</searchLink>; Presbyterian Medical Center, Jeonju, South Korea.<br /><searchLink fieldCode="AU" term="%22Park+JI%22">Park JI</searchLink>; Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, South Korea.<br /><searchLink fieldCode="AU" term="%22Yoo+SY%22">Yoo SY</searchLink>; Division of Cardiology, Department of Internal Medicine, Good Morning Hospital, Pyeongtaek, South Korea; Division of Cardiology, Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, South Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+Y%22">Ahn Y</searchLink>; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Chonnam National University, Gwangju, South Korea. Electronic address: cecilyk@jnu.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%222985213R%22">Lancet (London, England)</searchLink> [Lancet] 2025 Sep 06; Vol. 406 (10507), pp. 1032-1043. <i>Date of Electronic Publication: </i>2025 Aug 31.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>2985213R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1474-547X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201406736%22">01406736 </searchLink><i>NLM ISO Abbreviation: </i>Lancet <i>Subsets: </i>MEDLINE
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