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Rewiring of cortical glucose metabolism fuels human brain cancer growth.

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Title: Rewiring of cortical glucose metabolism fuels human brain cancer growth.
Authors: Scott AJ; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA., Mittal A; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA., Meghdadi B; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA., O'Brien A; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA., Bailleul J; Department of Radiation Oncology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA, USA., Sravya P; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA., Achreja A; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA.; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA.; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Zhou W; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA., Xu J; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA., Lin A; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA., Wilder-Romans K; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA., Liang N; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA., Kothari AU; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA., Korimerla N; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA., Edwards DM; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA., Wu Z; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Feng J; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Su S; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA., Zhang L; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Sajjakulnukit P; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Andren AC; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Park JO; Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, CA, USA., Ten Hoeve J; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Tarnal V; Department of Anesthesiology, University of Michigan, Ann Arbor, MI, USA.; Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA., Redic KA; Department of Pharmacy Services, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA., Qi NR; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA., Fischer JL; Bruker Daltonics, Billerica, MA, USA., Yang E; Bruker Daltonics, Billerica, MA, USA., Regan MS; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Stopka SA; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Baquer G; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Suresh K; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Sarkaria JN; Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USA., Lawrence TS; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA., Venneti S; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Agar NYR; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Vlashi E; Department of Radiation Oncology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA, USA., Lyssiotis CA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA. clyssiot@umich.edu.; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, USA. clyssiot@umich.edu.; Department of Internal Medicine, Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA. clyssiot@umich.edu., Al-Holou WN; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA. wna@med.umich.edu.; Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA. wna@med.umich.edu., Nagrath D; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA. dnagrath@umich.edu.; Laboratory for Systems Biology of Human Diseases, University of Michigan, Ann Arbor, MI, USA. dnagrath@umich.edu.; Biointerfaces Institute, University of Michigan, Ann Arbor, MI, USA. dnagrath@umich.edu.; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA. dnagrath@umich.edu., Wahl DR; Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA. dwahl@med.umich.edu.; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA. dwahl@med.umich.edu.; Department of Neurosurgery, University of Michigan, Ann Arbor, MI, USA. dwahl@med.umich.edu.
Source: Nature [Nature] 2025 Oct; Vol. 646 (8084), pp. 413-422. Date of Electronic Publication: 2025 Sep 03.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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