Design, synthesis, biological and computational evaluation of novel S/N-glycerolyl and peptide-conjugated [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent CDK2 inhibitors for anticancer therapy.
Saved in:
| Title: | Design, synthesis, biological and computational evaluation of novel S/N-glycerolyl and peptide-conjugated [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent CDK2 inhibitors for anticancer therapy. |
|---|---|
| Authors: | Nagy IM; Medicinal Chemistry Department, Menoufia University, Shebin El-Koam 32511, Egypt. Electronic address: ibrahim.mostafa24@science.menofia.edu.eg., El-Sayed HA; Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Koam 32511, Egypt., Abdel-Rahman AA; Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Koam 32511, Egypt. Electronic address: adel.nassar@science.menofia.edu.eg. |
| Source: | Bioorganic chemistry [Bioorg Chem] 2025 Oct; Vol. 165, pp. 108952. Date of Electronic Publication: 2025 Sep 02. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
Be the first to leave a comment!
