Cideb knockdown in mice increases mitochondrial fat oxidation and reverses hepatic steatosis and insulin resistance by the plasma membrane sn-1,2-DAGs-PKCε-insulin receptor kinaseT1150 pathway.
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| Title: | Cideb knockdown in mice increases mitochondrial fat oxidation and reverses hepatic steatosis and insulin resistance by the plasma membrane sn-1,2-DAGs-PKCε-insulin receptor kinaseT1150 pathway. |
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| Authors: | Zheng J; Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Gaspar RC; Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Sakuma I; Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.; Department of Molecular Diagnosis Graduate School of Medicine, Chiba University, Chiba, Japan., Hubbard BT; Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.; Department of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT, USA., Zhang D; Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Nasiri A; Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Kahn M; Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Perelis M; Ionis Pharmaceuticals, Carlsbad, CA, USA., Samuel VT; Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Petersen KF; Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA., Shulman GI; Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA. gerald.shulman@yale.edu.; Department of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT, USA. gerald.shulman@yale.edu.; Howard Hughes Medical Institute, Chevy Chase, MD, USA. gerald.shulman@yale.edu. |
| Source: | Diabetologia [Diabetologia] 2025 Dec; Vol. 68 (12), pp. 2906-2920. Date of Electronic Publication: 2025 Sep 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0006777 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0428 (Electronic) Linking ISSN: 0012186X NLM ISO Abbreviation: Diabetologia Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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