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Identifying a Vaginal Microbiome-Derived Selective Antibiotic Metabolite via Microbiome Pharmacology Analysis.

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Title: Identifying a Vaginal Microbiome-Derived Selective Antibiotic Metabolite via Microbiome Pharmacology Analysis.
Authors: Jena S; Weldon School of Biomedical Engineering, Purdue University, West Lafayette IN., Lawore D; Weldon School of Biomedical Engineering, Purdue University, West Lafayette IN., Briones JM; Weldon School of Biomedical Engineering, Purdue University, West Lafayette IN., Birse K; Department of Obstetrics and Gynecology, University of Manitoba, Winnipeg Canada.; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH., Lamont A; Department of Obstetrics and Gynecology, University of Manitoba, Winnipeg Canada., Mackelprang RD; Department of Global Health, University of Washington, Seattle USA., Noel-Romas L; Department of Obstetrics and Gynecology, University of Manitoba, Winnipeg Canada.; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH., Perner M; Medical Microbiology and Infectious Disease University of Manitoba, Winnipeg Canada., Hou X; Department of Global Health, University of Washington, Seattle USA., Irungu E; Partners in Health Research and Development, Kenya Medical Research Institute, Nairobi Kenya., Mugo N; Department of Global Health, University of Washington, Seattle USA.; Partners in Health Research and Development, Kenya Medical Research Institute, Nairobi Kenya., Knodel S; Department of Obstetrics and Gynecology, University of Manitoba, Winnipeg Canada.; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH., Brubaker SD; Graduate School of Public Health, University of Pittsburgh, Pittsburgh USA., Muwonge TR; Infectious Disease Institute, Makerere University, Makerere, Kampala Uganda., Katabira E; Infectious Disease Institute, Makerere University, Makerere, Kampala Uganda., Hughes SM; Department of Obstetrics and Gynecology, University of Washington, Seattle USA., Calienes FL; Fred Hutchinson Cancer Research Center, Seattle USA., Krajci R; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH., Liu R; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH., Nemecio D; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH., Hladik F; Department of Obstetrics and Gynecology, University of Washington, Seattle USA.; Fred Hutchinson Cancer Research Center, Seattle USA.; Department of Medicine, University of Washington, Seattle USA., Lingappa J; Department of Global Health, University of Washington, Seattle USA.; Department of Medicine, University of Washington, Seattle USA.; Department of Pediatrics, University of Washington, Seattle USA., Burgener AD; Department of Obstetrics and Gynecology, University of Manitoba, Winnipeg Canada.; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH.; Department of Medicine Solna, Karolinska Institutet, Framstegsgatan Sweden., Berard AR; Department of Obstetrics and Gynecology, University of Manitoba, Winnipeg Canada.; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH., Green LN; Weldon School of Biomedical Engineering, Purdue University, West Lafayette IN., Brubaker DK; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH.; The Blood Heart Lung Immunology Research Center, Case Western Reserve University, University Hospitals of Cleveland, Cleveland, OH, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Sep 05. Date of Electronic Publication: 2025 Sep 05.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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  Data: Identifying a Vaginal Microbiome-Derived Selective Antibiotic Metabolite via Microbiome Pharmacology Analysis.
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  Data: <searchLink fieldCode="AU" term="%22Jena+S%22">Jena S</searchLink>; Weldon School of Biomedical Engineering, Purdue University, West Lafayette IN.<br /><searchLink fieldCode="AU" term="%22Lawore+D%22">Lawore D</searchLink>; Weldon School of Biomedical Engineering, Purdue University, West Lafayette IN.<br /><searchLink fieldCode="AU" term="%22Briones+JM%22">Briones JM</searchLink>; Weldon School of Biomedical Engineering, Purdue University, West Lafayette IN.<br /><searchLink fieldCode="AU" term="%22Birse+K%22">Birse K</searchLink>; Department of Obstetrics and Gynecology, University of Manitoba, Winnipeg Canada.; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH.<br /><searchLink fieldCode="AU" term="%22Lamont+A%22">Lamont A</searchLink>; Department of Obstetrics and Gynecology, University of Manitoba, Winnipeg Canada.<br /><searchLink fieldCode="AU" term="%22Mackelprang+RD%22">Mackelprang RD</searchLink>; Department of Global Health, University of Washington, Seattle USA.<br /><searchLink fieldCode="AU" term="%22Noel-Romas+L%22">Noel-Romas L</searchLink>; Department of Obstetrics and Gynecology, University of Manitoba, Winnipeg Canada.; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH.<br /><searchLink fieldCode="AU" term="%22Perner+M%22">Perner M</searchLink>; Medical Microbiology and Infectious Disease University of Manitoba, Winnipeg Canada.<br /><searchLink fieldCode="AU" term="%22Hou+X%22">Hou X</searchLink>; Department of Global Health, University of Washington, Seattle USA.<br /><searchLink fieldCode="AU" term="%22Irungu+E%22">Irungu E</searchLink>; Partners in Health Research and Development, Kenya Medical Research Institute, Nairobi Kenya.<br /><searchLink fieldCode="AU" term="%22Mugo+N%22">Mugo N</searchLink>; Department of Global Health, University of Washington, Seattle USA.; Partners in Health Research and Development, Kenya Medical Research Institute, Nairobi Kenya.<br /><searchLink fieldCode="AU" term="%22Knodel+S%22">Knodel S</searchLink>; Department of Obstetrics and Gynecology, University of Manitoba, Winnipeg Canada.; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH.<br /><searchLink fieldCode="AU" term="%22Brubaker+SD%22">Brubaker SD</searchLink>; Graduate School of Public Health, University of Pittsburgh, Pittsburgh USA.<br /><searchLink fieldCode="AU" term="%22Muwonge+TR%22">Muwonge TR</searchLink>; Infectious Disease Institute, Makerere University, Makerere, Kampala Uganda.<br /><searchLink fieldCode="AU" term="%22Katabira+E%22">Katabira E</searchLink>; Infectious Disease Institute, Makerere University, Makerere, Kampala Uganda.<br /><searchLink fieldCode="AU" term="%22Hughes+SM%22">Hughes SM</searchLink>; Department of Obstetrics and Gynecology, University of Washington, Seattle USA.<br /><searchLink fieldCode="AU" term="%22Calienes+FL%22">Calienes FL</searchLink>; Fred Hutchinson Cancer Research Center, Seattle USA.<br /><searchLink fieldCode="AU" term="%22Krajci+R%22">Krajci R</searchLink>; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH.<br /><searchLink fieldCode="AU" term="%22Liu+R%22">Liu R</searchLink>; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH.<br /><searchLink fieldCode="AU" term="%22Nemecio+D%22">Nemecio D</searchLink>; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH.<br /><searchLink fieldCode="AU" term="%22Hladik+F%22">Hladik F</searchLink>; Department of Obstetrics and Gynecology, University of Washington, Seattle USA.; Fred Hutchinson Cancer Research Center, Seattle USA.; Department of Medicine, University of Washington, Seattle USA.<br /><searchLink fieldCode="AU" term="%22Lingappa+J%22">Lingappa J</searchLink>; Department of Global Health, University of Washington, Seattle USA.; Department of Medicine, University of Washington, Seattle USA.; Department of Pediatrics, University of Washington, Seattle USA.<br /><searchLink fieldCode="AU" term="%22Burgener+AD%22">Burgener AD</searchLink>; Department of Obstetrics and Gynecology, University of Manitoba, Winnipeg Canada.; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH.; Department of Medicine Solna, Karolinska Institutet, Framstegsgatan Sweden.<br /><searchLink fieldCode="AU" term="%22Berard+AR%22">Berard AR</searchLink>; Department of Obstetrics and Gynecology, University of Manitoba, Winnipeg Canada.; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH.<br /><searchLink fieldCode="AU" term="%22Green+LN%22">Green LN</searchLink>; Weldon School of Biomedical Engineering, Purdue University, West Lafayette IN.<br /><searchLink fieldCode="AU" term="%22Brubaker+DK%22">Brubaker DK</searchLink>; Center for Global Health and Disease, Department of Pathology, Case Western Reserve University, Cleveland OH.; The Blood Heart Lung Immunology Research Center, Case Western Reserve University, University Hospitals of Cleveland, Cleveland, OH, USA.
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        Value: 10.1101/2025.08.28.672927
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        Text: English
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