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Molecular prosthetics for CFTR designed for anion selectivity outperform amphotericin B in cultured cystic fibrosis airway epithelia.

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Title: Molecular prosthetics for CFTR designed for anion selectivity outperform amphotericin B in cultured cystic fibrosis airway epithelia.
Authors: Marin-Toledo JP; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Greenan D; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Celis N; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Haske L; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Lewandowska A; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Rakowski CK; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Shastry S; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Maji A; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Green KJ; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Pogorelov TV; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Welsh MJ; Department of Internal Medicine, Pappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Howard Hughes Medical Institute, Iowa City, IA, USA., Thornell IM; Department of Internal Medicine, Pappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Burke MD; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Molecule Maker Lab, Beckman Institute for Advanced Science and Technology, Urbana, IL, USA.; Molecule Maker Lab Institute, Carl R. Woese Institute for Genomic Biology. Urbana, IL, USA.; Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Aug 28. Date of Electronic Publication: 2025 Aug 28.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Marin-Toledo+JP%22">Marin-Toledo JP</searchLink>; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Greenan+D%22">Greenan D</searchLink>; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Celis+N%22">Celis N</searchLink>; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Haske+L%22">Haske L</searchLink>; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Lewandowska+A%22">Lewandowska A</searchLink>; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Rakowski+CK%22">Rakowski CK</searchLink>; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Shastry+S%22">Shastry S</searchLink>; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Maji+A%22">Maji A</searchLink>; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Green+KJ%22">Green KJ</searchLink>; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Pogorelov+TV%22">Pogorelov TV</searchLink>; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.<br /><searchLink fieldCode="AU" term="%22Welsh+MJ%22">Welsh MJ</searchLink>; Department of Internal Medicine, Pappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.; Howard Hughes Medical Institute, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Thornell+IM%22">Thornell IM</searchLink>; Department of Internal Medicine, Pappajohn Biomedical Institute, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Burke+MD%22">Burke MD</searchLink>; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Molecule Maker Lab, Beckman Institute for Advanced Science and Technology, Urbana, IL, USA.; Molecule Maker Lab Institute, Carl R. Woese Institute for Genomic Biology. Urbana, IL, USA.; Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA.; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
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