METTL1-mediated m7G methylation of Sarm1 mRNA promotes macrophage inflammatory responses and multiple organ injury.
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| Title: | METTL1-mediated m7G methylation of Sarm1 mRNA promotes macrophage inflammatory responses and multiple organ injury. |
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| Authors: | Hou C; School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, Anhui, China., Zhang XR; School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China.; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, Anhui, China., Wei J; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, Anhui, China.; Department of Nephrology, Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Wang JN; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, Anhui, China., Gao J; School of Medicine, Anhui University of Science and Technology, Huainan, Anhui, China., Wang ZJ; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, Anhui, China.; Department of Nephrology, Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Xie SS; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, Anhui, China., Chen T; School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China., Sun T; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, Anhui, China., Pu T; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, Anhui, China., Yu JT; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, Anhui, China., Suo XG; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, Anhui, China., Mei ZY; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, Anhui, China., Zhang FR; School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China., Jin J; School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China., Zhao WM; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, Anhui, China.; Department of Nephrology, Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China., Shen YX; School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China., Meng XM; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Anhui Institute of Innovative Drugs, School of Pharmacy, Anhui Medical University, Hefei, Anhui, China. |
| Source: | Science immunology [Sci Immunol] 2025 Sep 05; Vol. 10 (111), pp. eadv4810. Date of Electronic Publication: 2025 Sep 05. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2470-9468 |
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| DOI: | 10.1126/sciimmunol.adv4810 |
