PAX3-FOXO1 Drives Targetable Cell State-Dependent Metabolic Vulnerabilities in Rhabdomyosarcoma.

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Title: PAX3-FOXO1 Drives Targetable Cell State-Dependent Metabolic Vulnerabilities in Rhabdomyosarcoma.
Authors: Paras KI; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, New York., Brunner JS; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York., Montero AM; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, New York., Boyer JA; Ludwig Cancer Institute, Princeton Branch, Princeton University, Princeton, New Jersey., Jackson BT; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York., Chakraborty S; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York., Xie A; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York., Guillan K; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York., Siddiquee A; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York., Pajuelo Torres L; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, New York., Rabinowitz JD; Ludwig Cancer Institute, Princeton Branch, Princeton University, Princeton, New Jersey.; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey.; Department of Chemistry, Princeton University, Princeton, New Jersey., Kung AL; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York., You D; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York., Dela Cruz FS; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York., Finley LWS; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.
Source: Cancer research [Cancer Res] 2025 Dec 01; Vol. 85 (23), pp. 4718-4733.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE
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  Data: PAX3-FOXO1 Drives Targetable Cell State-Dependent Metabolic Vulnerabilities in Rhabdomyosarcoma.
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  Data: <searchLink fieldCode="AU" term="%22Paras+KI%22">Paras KI</searchLink>; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, New York.<br /><searchLink fieldCode="AU" term="%22Brunner+JS%22">Brunner JS</searchLink>; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Montero+AM%22">Montero AM</searchLink>; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, New York.<br /><searchLink fieldCode="AU" term="%22Boyer+JA%22">Boyer JA</searchLink>; Ludwig Cancer Institute, Princeton Branch, Princeton University, Princeton, New Jersey.<br /><searchLink fieldCode="AU" term="%22Jackson+BT%22">Jackson BT</searchLink>; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Chakraborty+S%22">Chakraborty S</searchLink>; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Xie+A%22">Xie A</searchLink>; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Guillan+K%22">Guillan K</searchLink>; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Siddiquee+A%22">Siddiquee A</searchLink>; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Pajuelo+Torres+L%22">Pajuelo Torres L</searchLink>; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.; Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, New York.<br /><searchLink fieldCode="AU" term="%22Rabinowitz+JD%22">Rabinowitz JD</searchLink>; Ludwig Cancer Institute, Princeton Branch, Princeton University, Princeton, New Jersey.; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, New Jersey.; Department of Chemistry, Princeton University, Princeton, New Jersey.<br /><searchLink fieldCode="AU" term="%22Kung+AL%22">Kung AL</searchLink>; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22You+D%22">You D</searchLink>; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Dela+Cruz+FS%22">Dela Cruz FS</searchLink>; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.<br /><searchLink fieldCode="AU" term="%22Finley+LWS%22">Finley LWS</searchLink>; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York.
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