Association of preoperative nocturnal hypoxaemia nadir and fentanyl ventilatory sensitivity in children with obstructive sleep apnoea undergoing general anaesthesia: a multicentre clinical cohort study.

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Title: Association of preoperative nocturnal hypoxaemia nadir and fentanyl ventilatory sensitivity in children with obstructive sleep apnoea undergoing general anaesthesia: a multicentre clinical cohort study.
Authors: Adler AC; Department of Anesthesiology, Perioperative and Pain Medicine, Texas Children's Hospital, Houston, TX, USA; Baylor College of Medicine, Houston, TX, USA. Electronic address: adamcadler@gmail.com., Lin EE; Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Pennsylvania, Philadelphia, PA, USA; The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Messner AH; Baylor College of Medicine, Houston, TX, USA; Department of Otolaryngology/Head & Neck Surgery, Baylor College of Medicine, Houston, TX, USA., Rosenberg TL; Baylor College of Medicine, Houston, TX, USA; Department of Otolaryngology/Head & Neck Surgery, Baylor College of Medicine, Houston, TX, USA., Pecorella S; Department of Anesthesiology, Atrium Health, Wake Forest Baptist, Winston-Salem, NC, USA; Wake Forest University School of Medicine, Winston-Salem, NC, USA., Keleghan A; Department of Anesthesiology, Atrium Health, Wake Forest Baptist, Winston-Salem, NC, USA., Faircloth S; Department of Anesthesiology, Atrium Health, Wake Forest Baptist, Winston-Salem, NC, USA., Templeton TW; Department of Anesthesiology, Atrium Health, Wake Forest Baptist, Winston-Salem, NC, USA; Wake Forest University School of Medicine, Winston-Salem, NC, USA., Harris L; Department of Anesthesiology, Atrium Health, Wake Forest Baptist, Winston-Salem, NC, USA., Khan SA; Department of Anesthesiology, Division of Pediatric Anesthesiology, UT Health Houston, Houston, TX, USA; McGovern Medical School, Houston, TX, USA., Pednekar GS; Department of Anesthesiology, Division of Pediatric Anesthesiology, UT Health Houston, Houston, TX, USA; McGovern Medical School, Houston, TX, USA., Nguyen DT; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Chandrakantan A; Department of Anesthesiology, Perioperative and Pain Medicine, Texas Children's Hospital, Houston, TX, USA; Baylor College of Medicine, Houston, TX, USA., von Ungern-Sternberg BS; Department of Anaesthesia and Pain Management, Perth Children's Hospital, Perth, WA, Australia; Division of Emergency Medicine, Anaesthesia and Pain Medicine, The University of Western Australia, Perth, WA, Australia; Institute for Paediatric Perioperative Excellence, The University of Western Australia, Perth, WA, Australia; Perioperative Medicine Team, Perioperative Care Program, The Kids Research Institute Australia, Perth, WA, Australia.
Source: British journal of anaesthesia [Br J Anaesth] 2025 Nov; Vol. 135 (5), pp. 1518-1527. Date of Electronic Publication: 2025 Sep 05.
Publication Type: Journal Article; Multicenter Study; Observational Study
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 0372541 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1471-6771 (Electronic) Linking ISSN: 00070912 NLM ISO Abbreviation: Br J Anaesth Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Association of preoperative nocturnal hypoxaemia nadir and fentanyl ventilatory sensitivity in children with obstructive sleep apnoea undergoing general anaesthesia: a multicentre clinical cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Adler+AC%22">Adler AC</searchLink>; Department of Anesthesiology, Perioperative and Pain Medicine, Texas Children's Hospital, Houston, TX, USA; Baylor College of Medicine, Houston, TX, USA. Electronic address: adamcadler@gmail.com.<br /><searchLink fieldCode="AU" term="%22Lin+EE%22">Lin EE</searchLink>; Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Pennsylvania, Philadelphia, PA, USA; The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Messner+AH%22">Messner AH</searchLink>; Baylor College of Medicine, Houston, TX, USA; Department of Otolaryngology/Head & Neck Surgery, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Rosenberg+TL%22">Rosenberg TL</searchLink>; Baylor College of Medicine, Houston, TX, USA; Department of Otolaryngology/Head & Neck Surgery, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Pecorella+S%22">Pecorella S</searchLink>; Department of Anesthesiology, Atrium Health, Wake Forest Baptist, Winston-Salem, NC, USA; Wake Forest University School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Keleghan+A%22">Keleghan A</searchLink>; Department of Anesthesiology, Atrium Health, Wake Forest Baptist, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Faircloth+S%22">Faircloth S</searchLink>; Department of Anesthesiology, Atrium Health, Wake Forest Baptist, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Templeton+TW%22">Templeton TW</searchLink>; Department of Anesthesiology, Atrium Health, Wake Forest Baptist, Winston-Salem, NC, USA; Wake Forest University School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Harris+L%22">Harris L</searchLink>; Department of Anesthesiology, Atrium Health, Wake Forest Baptist, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Khan+SA%22">Khan SA</searchLink>; Department of Anesthesiology, Division of Pediatric Anesthesiology, UT Health Houston, Houston, TX, USA; McGovern Medical School, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Pednekar+GS%22">Pednekar GS</searchLink>; Department of Anesthesiology, Division of Pediatric Anesthesiology, UT Health Houston, Houston, TX, USA; McGovern Medical School, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+DT%22">Nguyen DT</searchLink>; Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Chandrakantan+A%22">Chandrakantan A</searchLink>; Department of Anesthesiology, Perioperative and Pain Medicine, Texas Children's Hospital, Houston, TX, USA; Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22von+Ungern-Sternberg+BS%22">von Ungern-Sternberg BS</searchLink>; Department of Anaesthesia and Pain Management, Perth Children's Hospital, Perth, WA, Australia; Division of Emergency Medicine, Anaesthesia and Pain Medicine, The University of Western Australia, Perth, WA, Australia; Institute for Paediatric Perioperative Excellence, The University of Western Australia, Perth, WA, Australia; Perioperative Medicine Team, Perioperative Care Program, The Kids Research Institute Australia, Perth, WA, Australia.
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  Data: <searchLink fieldCode="JN" term="%220372541%22">British journal of anaesthesia</searchLink> [Br J Anaesth] 2025 Nov; Vol. 135 (5), pp. 1518-1527. <i>Date of Electronic Publication: </i>2025 Sep 05.
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  Data: Journal Article; Multicenter Study; Observational Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0372541 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-6771 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200070912%22">00070912 </searchLink><i>NLM ISO Abbreviation: </i>Br J Anaesth <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bja.2025.07.059
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        Text: English
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      – TitleFull: Association of preoperative nocturnal hypoxaemia nadir and fentanyl ventilatory sensitivity in children with obstructive sleep apnoea undergoing general anaesthesia: a multicentre clinical cohort study.
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              Text: 2025 Nov
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