Remodeling the sarcoma microenvironment by simultaneous targeting of urokinase-type plasminogen activator receptors and epidermal growth factor receptors to promote antitumor activity.
Saved in:
| Title: | Remodeling the sarcoma microenvironment by simultaneous targeting of urokinase-type plasminogen activator receptors and epidermal growth factor receptors to promote antitumor activity. |
|---|---|
| Authors: | Schulte AJ; Animal Cancer Care and Research Program, University of Minnesota, St Paul, Minnesota; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota., Lewellen M; Animal Cancer Care and Research Program, University of Minnesota, St Paul, Minnesota; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota., Durose W; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota; Division of Pediatric, Blood and Masrrow Transplantation, Department of Pediatrics, Medical School, University of Minnesota, Minneapolis, Minnesota., Nolan E; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota; Division of Pediatric, Blood and Masrrow Transplantation, Department of Pediatrics, Medical School, University of Minnesota, Minneapolis, Minnesota., Taghizadeh L; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota; Division of Pediatric, Blood and Masrrow Transplantation, Department of Pediatrics, Medical School, University of Minnesota, Minneapolis, Minnesota., Todhunter D; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota; Department of Therapeutic Radiology, Medical School, University of Minnesota, Minneapolis, Minnesota., Bush C; Animal Cancer Care and Research Program, University of Minnesota, St Paul, Minnesota; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota., Lang HP; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota; Comparative Molecular Biosciences Graduate Program, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota; Center for Immunology, University of Minnesota, Minneapolis, Minnesota., Brown ME; University Imaging Center, University of Minnesota, Minneapolis, Minnesota., DePauw TA; Animal Cancer Care and Research Program, University of Minnesota, St Paul, Minnesota; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota; Microbiology, Immunology, and Cancer Biology Graduate Program, University of Minnesota, Minneapolis, Minnesota., Makielski KM; Animal Cancer Care and Research Program, University of Minnesota, St Paul, Minnesota; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota., Kim JH; Animal Cancer Care and Research Program, University of Minnesota, St Paul, Minnesota; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota., Burt LE; Animal Cancer Care and Research Program, University of Minnesota, St Paul, Minnesota; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota., Overn P; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota., Forster CL; The University of Minnesota Biological Materials Procurement Network (BioNet), University of Minnesota, Minneapolis, Minnesota., Seelig DM; Animal Cancer Care and Research Program, University of Minnesota, St Paul, Minnesota; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota., O'Sullivan MG; Animal Cancer Care and Research Program, University of Minnesota, St Paul, Minnesota; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota., Weigel BJ; Animal Cancer Care and Research Program, University of Minnesota, St Paul, Minnesota; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota; Division of Pediatric, Blood and Masrrow Transplantation, Department of Pediatrics, Medical School, University of Minnesota, Minneapolis, Minnesota., Murugan P; Animal Cancer Care and Research Program, University of Minnesota, St Paul, Minnesota; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota; The University of Minnesota Biological Materials Procurement Network (BioNet), University of Minnesota, Minneapolis, Minnesota; Department of Laboratory Medicine and Pathology, Medical School, University of Minnesota, Minneapolis, Minnesota., Cutter GR; Department of Biostatistics, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama., Lund TC; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota; Division of Pediatric, Blood and Masrrow Transplantation, Department of Pediatrics, Medical School, University of Minnesota, Minneapolis, Minnesota; Center for Immunology, University of Minnesota, Minneapolis, Minnesota; Stem Cell Institute, University of Minnesota, Minneapolis, Minnesota., Vallera DA; Animal Cancer Care and Research Program, University of Minnesota, St Paul, Minnesota; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota; Department of Therapeutic Radiology, Medical School, University of Minnesota, Minneapolis, Minnesota., Modiano JF; Animal Cancer Care and Research Program, University of Minnesota, St Paul, Minnesota; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota; Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota; Center for Immunology, University of Minnesota, Minneapolis, Minnesota; Department of Laboratory Medicine and Pathology, Medical School, University of Minnesota, Minneapolis, Minnesota; Stem Cell Institute, University of Minnesota, Minneapolis, Minnesota; Institute for Engineering in Medicine, University of Minnesota, Minneapolis, Minnesota. Electronic address: modiano@umn.edu. |
| Source: | The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2025 Sep; Vol. 392 (9), pp. 103674. Date of Electronic Publication: 2025 Aug 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0376362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0103 (Electronic) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
Be the first to leave a comment!
