YangXue QingNao Wan ameliorates vascular dementia in 2-VO rats via inhibition of ferroptosis.

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Title: YangXue QingNao Wan ameliorates vascular dementia in 2-VO rats via inhibition of ferroptosis.
Authors: Zhang YJ; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Liang HB; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Wang XY; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China; China Rehabilitation Science Institute, China Rehabilitation Research Center, Beijing, China., Chen FK; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Guo S; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Yang C; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Li AQ; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Jiao YQ; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Yan L; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Pan CS; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Huo XM; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Sun K; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Ma ZZ; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China., Han JY; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China. Electronic address: hanjingyan@bjmu.edu.cn., Liu J; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China. Electronic address: liujianpku@bjmu.edu.cn.
Source: Journal of ethnopharmacology [J Ethnopharmacol] 2026 Jan 10; Vol. 354, pp. 120550. Date of Electronic Publication: 2025 Sep 05.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Sequoia Country of Publication: Ireland NLM ID: 7903310 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7573 (Electronic) Linking ISSN: 03788741 NLM ISO Abbreviation: J Ethnopharmacol Subsets: MEDLINE
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  Data: YangXue QingNao Wan ameliorates vascular dementia in 2-VO rats via inhibition of ferroptosis.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+YJ%22">Zhang YJ</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Liang+HB%22">Liang HB</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+XY%22">Wang XY</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China; China Rehabilitation Science Institute, China Rehabilitation Research Center, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Chen+FK%22">Chen FK</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Guo+S%22">Guo S</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Yang+C%22">Yang C</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Li+AQ%22">Li AQ</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Jiao+YQ%22">Jiao YQ</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Yan+L%22">Yan L</searchLink>; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Pan+CS%22">Pan CS</searchLink>; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Huo+XM%22">Huo XM</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Sun+K%22">Sun K</searchLink>; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Ma+ZZ%22">Ma ZZ</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Han+JY%22">Han JY</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Tasly Microcirculation Research Center, Peking University Health Science Center, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China. Electronic address: hanjingyan@bjmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Integration of Chinese and Western Medicine, School of Basic Medical Sciences, Peking University, Beijing, China; Academy of Integration of Chinese and Western Medicine, Peking University Health Science Center, Beijing, China; The Key Discipline for Integration of Chinese and Western Basic Medicine (Microcirculation) of the National Administration of Traditional Chinese Medicine, Beijing, China; Key Laboratory of Stasis and Phlegm, State Administration of Traditional Chinese Medicine of the People's Republic of China, Beijing, China; Beijing Microvascular Institute of Integration of Chinese and Western Medicine, Beijing, China. Electronic address: liujianpku@bjmu.edu.cn.
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        Value: 10.1016/j.jep.2025.120550
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