View in EDS HTML Full Text PDF Full Text

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration-resistant prostate cancer.

Saved in:
Bibliographic Details
Title: PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration-resistant prostate cancer.
Authors: Cunningham ML; Department of Cell Biology and Regenerative Medicine, Thomas Jefferson University, Philadelphia, PA, USA.; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA., Vasquez-Gonzalez J; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA., Barnada SM; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA., Tchotorlishvili S; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA., Jones L; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA., Maguire R; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA., Lewis G; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA., Rizwan K; Department of Medicine, Section Hematology/Oncology, Baylor College of Medicine, Houston, TX, USA., Deng J; Department of Medicine, Section Hematology/Oncology, Baylor College of Medicine, Houston, TX, USA., Koachar S; Department of Medicine, Section Hematology/Oncology, Baylor College of Medicine, Houston, TX, USA., Patel D; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA., Shankle H; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA., Mulders T; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA., Ajmal N; Department of Pathology and Genomic Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, USA., Solomides C; Department of Pathology and Genomic Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, USA., Alnemri ES; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA., Alnemri TF; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA., Shafi AA; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA., Gomella LG; Sidney Kimmel Comprehensive Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.; Department of Urology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA., Kelly WK; Sidney Kimmel Comprehensive Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.; Department of Medical Oncology, The Sidney Kimmel Comprehensive Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA., McMahon SB; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA., Schiewer MJ; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.; Department of Urology, Thomas Jefferson University, Philadelphia, PA, USA.
Source: Molecular oncology [Mol Oncol] 2026 Feb; Vol. 20 (2), pp. 369-388. Date of Electronic Publication: 2025 Sep 07.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40915979
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration-resistant prostate cancer.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Cunningham+ML%22">Cunningham ML</searchLink>; Department of Cell Biology and Regenerative Medicine, Thomas Jefferson University, Philadelphia, PA, USA.; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Vasquez-Gonzalez+J%22">Vasquez-Gonzalez J</searchLink>; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Barnada+SM%22">Barnada SM</searchLink>; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Tchotorlishvili+S%22">Tchotorlishvili S</searchLink>; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Jones+L%22">Jones L</searchLink>; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Maguire+R%22">Maguire R</searchLink>; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+G%22">Lewis G</searchLink>; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Rizwan+K%22">Rizwan K</searchLink>; Department of Medicine, Section Hematology/Oncology, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Deng+J%22">Deng J</searchLink>; Department of Medicine, Section Hematology/Oncology, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Koachar+S%22">Koachar S</searchLink>; Department of Medicine, Section Hematology/Oncology, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Patel+D%22">Patel D</searchLink>; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Shankle+H%22">Shankle H</searchLink>; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Mulders+T%22">Mulders T</searchLink>; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ajmal+N%22">Ajmal N</searchLink>; Department of Pathology and Genomic Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Solomides+C%22">Solomides C</searchLink>; Department of Pathology and Genomic Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Alnemri+ES%22">Alnemri ES</searchLink>; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Alnemri+TF%22">Alnemri TF</searchLink>; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Shafi+AA%22">Shafi AA</searchLink>; Center for Prostate Disease Research, Murtha Cancer Center Research Program, Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.; The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Gomella+LG%22">Gomella LG</searchLink>; Sidney Kimmel Comprehensive Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.; Department of Urology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kelly+WK%22">Kelly WK</searchLink>; Sidney Kimmel Comprehensive Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.; Department of Medical Oncology, The Sidney Kimmel Comprehensive Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22McMahon+SB%22">McMahon SB</searchLink>; Department of Biochemistry and Molecular Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Schiewer+MJ%22">Schiewer MJ</searchLink>; Department of Pharmacology, Physiology, and Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.; Sidney Kimmel Comprehensive Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA.; Department of Urology, Thomas Jefferson University, Philadelphia, PA, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101308230%22">Molecular oncology</searchLink> [Mol Oncol] 2026 Feb; Vol. 20 (2), pp. 369-388. <i>Date of Electronic Publication: </i>2025 Sep 07.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Inc%22">John Wiley & Sons, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101308230 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-0261 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215747891%22">15747891 </searchLink><i>NLM ISO Abbreviation: </i>Mol Oncol <i>Subsets: </i>MEDLINE; In Process
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40915979
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1002/1878-0261.70098
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 369
    Titles:
      – TitleFull: PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration-resistant prostate cancer.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Cunningham ML
      – PersonEntity:
          Name:
            NameFull: Vasquez-Gonzalez J
      – PersonEntity:
          Name:
            NameFull: Barnada SM
      – PersonEntity:
          Name:
            NameFull: Tchotorlishvili S
      – PersonEntity:
          Name:
            NameFull: Jones L
      – PersonEntity:
          Name:
            NameFull: Maguire R
      – PersonEntity:
          Name:
            NameFull: Lewis G
      – PersonEntity:
          Name:
            NameFull: Rizwan K
      – PersonEntity:
          Name:
            NameFull: Deng J
      – PersonEntity:
          Name:
            NameFull: Koachar S
      – PersonEntity:
          Name:
            NameFull: Patel D
      – PersonEntity:
          Name:
            NameFull: Shankle H
      – PersonEntity:
          Name:
            NameFull: Mulders T
      – PersonEntity:
          Name:
            NameFull: Ajmal N
      – PersonEntity:
          Name:
            NameFull: Solomides C
      – PersonEntity:
          Name:
            NameFull: Alnemri ES
      – PersonEntity:
          Name:
            NameFull: Alnemri TF
      – PersonEntity:
          Name:
            NameFull: Shafi AA
      – PersonEntity:
          Name:
            NameFull: Gomella LG
      – PersonEntity:
          Name:
            NameFull: Kelly WK
      – PersonEntity:
          Name:
            NameFull: McMahon SB
      – PersonEntity:
          Name:
            NameFull: Schiewer MJ
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 02
              Text: 2026 Feb
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1878-0261
          Numbering:
            – Type: volume
              Value: 20
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: Molecular oncology
              Type: main
ResultId 1