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Diagnostic performance of Alzheimer's disease blood and CSF biomarkers in a Brazilian cohort with low educational attainment.

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Title: Diagnostic performance of Alzheimer's disease blood and CSF biomarkers in a Brazilian cohort with low educational attainment.
Authors: Borelli WV; Department of Morphological Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.; Memory Center, Hospital Moinhos de Vento, Porto Alegre, RS, Brazil.; Graduate Program in Biological Sciences: Pharmacology and Therapeutics (PPGFT), UFRGS, Porto Alegre, RS, Brazil., Ferreira PCL; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Brum WS; Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Graduate Program in Biological Sciences: Biochemistry (PPGBioq), UFRGS, Porto Alegre, RS, Brazil., Ferrari-Souza JP; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Graduate Program in Biological Sciences: Biochemistry (PPGBioq), UFRGS, Porto Alegre, RS, Brazil., Carello-Collar G; Graduate Program in Biological Sciences: Biochemistry (PPGBioq), UFRGS, Porto Alegre, RS, Brazil., Holz M; Cognitive and Behavioral Neurology Center, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil., Tizeli V; Cognitive and Behavioral Neurology Center, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil., Strelow MZ; Cognitive and Behavioral Neurology Center, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil., Formoso C; Cognitive and Behavioral Neurology Center, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil., Chaves MLF; Cognitive and Behavioral Neurology Center, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil., Rocha A; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Aguzzoli CS; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Global Brain Health Institute, University of California San Francisco (UCSF), San Francisco, USA.; Brain Institute of Rio Grande do Sul, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, RS, Brazil., Rohden F; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Graduate Program in Biological Sciences: Biochemistry (PPGBioq), UFRGS, Porto Alegre, RS, Brazil., Souza DG; Graduate Program in Biological Sciences: Biochemistry (PPGBioq), UFRGS, Porto Alegre, RS, Brazil., Schumacher Schuh AF; Graduate Program in Biological Sciences: Pharmacology and Therapeutics (PPGFT), UFRGS, Porto Alegre, RS, Brazil.; Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.; Department of Pharmacology, UFRGS, Porto Alegre, RS, Brazil., Povala G; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Bellaver B; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Graduate Program in Biological Sciences: Biochemistry (PPGBioq), UFRGS, Porto Alegre, RS, Brazil., Rosa-Neto P; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre Intégré Universitaire de Santé et de Services Sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Verdun, QC, Canada.; Department of Neurology and Neurosurgery, Psychiatry, and Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada.; The Peter O'Donnell Jr Brain Institute, University of Texas Southwestern Medical Centre, Dallas, TX, USA., Castilhos RM; Cognitive and Behavioral Neurology Center, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil., Pascoal TA; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Zimmer ER; Memory Center, Hospital Moinhos de Vento, Porto Alegre, RS, Brazil. eduardo.zimmer@hmv.org.br.; Graduate Program in Biological Sciences: Pharmacology and Therapeutics (PPGFT), UFRGS, Porto Alegre, RS, Brazil. eduardo.zimmer@hmv.org.br.; Graduate Program in Biological Sciences: Biochemistry (PPGBioq), UFRGS, Porto Alegre, RS, Brazil. eduardo.zimmer@hmv.org.br.; Brain Institute of Rio Grande do Sul, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, RS, Brazil. eduardo.zimmer@hmv.org.br.; Department of Pharmacology, UFRGS, Porto Alegre, RS, Brazil. eduardo.zimmer@hmv.org.br.; The McGill University Research Centre for Studies in Aging, McGill University, Montreal, QC, Canada. eduardo.zimmer@hmv.org.br.
Source: Molecular psychiatry [Mol Psychiatry] 2025 Dec; Vol. 30 (12), pp. 6090-6098. Date of Electronic Publication: 2025 Sep 08.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Diagnostic performance of Alzheimer's disease blood and CSF biomarkers in a Brazilian cohort with low educational attainment.
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  Data: <searchLink fieldCode="AU" term="%22Borelli+WV%22">Borelli WV</searchLink>; Department of Morphological Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.; Memory Center, Hospital Moinhos de Vento, Porto Alegre, RS, Brazil.; Graduate Program in Biological Sciences: Pharmacology and Therapeutics (PPGFT), UFRGS, Porto Alegre, RS, Brazil.<br /><searchLink fieldCode="AU" term="%22Ferreira+PCL%22">Ferreira PCL</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Brum+WS%22">Brum WS</searchLink>; Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Graduate Program in Biological Sciences: Biochemistry (PPGBioq), UFRGS, Porto Alegre, RS, Brazil.<br /><searchLink fieldCode="AU" term="%22Ferrari-Souza+JP%22">Ferrari-Souza JP</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Graduate Program in Biological Sciences: Biochemistry (PPGBioq), UFRGS, Porto Alegre, RS, Brazil.<br /><searchLink fieldCode="AU" term="%22Carello-Collar+G%22">Carello-Collar G</searchLink>; Graduate Program in Biological Sciences: Biochemistry (PPGBioq), UFRGS, Porto Alegre, RS, Brazil.<br /><searchLink fieldCode="AU" term="%22Holz+M%22">Holz M</searchLink>; Cognitive and Behavioral Neurology Center, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil.<br /><searchLink fieldCode="AU" term="%22Tizeli+V%22">Tizeli V</searchLink>; Cognitive and Behavioral Neurology Center, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil.<br /><searchLink fieldCode="AU" term="%22Strelow+MZ%22">Strelow MZ</searchLink>; Cognitive and Behavioral Neurology Center, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil.<br /><searchLink fieldCode="AU" term="%22Formoso+C%22">Formoso C</searchLink>; Cognitive and Behavioral Neurology Center, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil.<br /><searchLink fieldCode="AU" term="%22Chaves+MLF%22">Chaves MLF</searchLink>; Cognitive and Behavioral Neurology Center, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil.<br /><searchLink fieldCode="AU" term="%22Rocha+A%22">Rocha A</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Aguzzoli+CS%22">Aguzzoli CS</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Global Brain Health Institute, University of California San Francisco (UCSF), San Francisco, USA.; Brain Institute of Rio Grande do Sul, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, RS, Brazil.<br /><searchLink fieldCode="AU" term="%22Rohden+F%22">Rohden F</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Graduate Program in Biological Sciences: Biochemistry (PPGBioq), UFRGS, Porto Alegre, RS, Brazil.<br /><searchLink fieldCode="AU" term="%22Souza+DG%22">Souza DG</searchLink>; Graduate Program in Biological Sciences: Biochemistry (PPGBioq), UFRGS, Porto Alegre, RS, Brazil.<br /><searchLink fieldCode="AU" term="%22Schumacher+Schuh+AF%22">Schumacher Schuh AF</searchLink>; Graduate Program in Biological Sciences: Pharmacology and Therapeutics (PPGFT), UFRGS, Porto Alegre, RS, Brazil.; Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil.; Department of Pharmacology, UFRGS, Porto Alegre, RS, Brazil.<br /><searchLink fieldCode="AU" term="%22Povala+G%22">Povala G</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Bellaver+B%22">Bellaver B</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Graduate Program in Biological Sciences: Biochemistry (PPGBioq), UFRGS, Porto Alegre, RS, Brazil.<br /><searchLink fieldCode="AU" term="%22Rosa-Neto+P%22">Rosa-Neto P</searchLink>; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre Intégré Universitaire de Santé et de Services Sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Verdun, QC, Canada.; Department of Neurology and Neurosurgery, Psychiatry, and Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada.; The Peter O'Donnell Jr Brain Institute, University of Texas Southwestern Medical Centre, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Castilhos+RM%22">Castilhos RM</searchLink>; Cognitive and Behavioral Neurology Center, Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil.<br /><searchLink fieldCode="AU" term="%22Pascoal+TA%22">Pascoal TA</searchLink>; Department of Psychiatry, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Zimmer+ER%22">Zimmer ER</searchLink>; Memory Center, Hospital Moinhos de Vento, Porto Alegre, RS, Brazil. eduardo.zimmer@hmv.org.br.; Graduate Program in Biological Sciences: Pharmacology and Therapeutics (PPGFT), UFRGS, Porto Alegre, RS, Brazil. eduardo.zimmer@hmv.org.br.; Graduate Program in Biological Sciences: Biochemistry (PPGBioq), UFRGS, Porto Alegre, RS, Brazil. eduardo.zimmer@hmv.org.br.; Brain Institute of Rio Grande do Sul, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, RS, Brazil. eduardo.zimmer@hmv.org.br.; Department of Pharmacology, UFRGS, Porto Alegre, RS, Brazil. eduardo.zimmer@hmv.org.br.; The McGill University Research Centre for Studies in Aging, McGill University, Montreal, QC, Canada. eduardo.zimmer@hmv.org.br.
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  Data: <searchLink fieldCode="JN" term="%229607835%22">Molecular psychiatry</searchLink> [Mol Psychiatry] 2025 Dec; Vol. 30 (12), pp. 6090-6098. <i>Date of Electronic Publication: </i>2025 Sep 08.
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