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Phase II Dose-Randomized Study of Sunvozertinib in Platinum-Pretreated Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor Exon 20 Insertion Mutations (WU-KONG1B).

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Title: Phase II Dose-Randomized Study of Sunvozertinib in Platinum-Pretreated Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor Exon 20 Insertion Mutations (WU-KONG1B).
Authors: Yang JC; National Taiwan University Cancer Center and National Taiwan University Hospital, Taipei, Taiwan., Wang M; Peking Union Medical College Hospital, Beijing, China., Doucet L; Institut de Cancérologie de l'Ouest (ICO)-René Gauducheau, Saint-Herblain, France., Fan Y; Zhejiang Cancer Hospital, Hangzhou, China., Lv D; Taizhou Hospital of Zhejiang Province, Linhai, China., Sun M; Jinan Central Hospital, Jinan, China., Huang D; Tianjin Medical University Cancer Institute & Hospital, Tianjin, China., Greillier L; CHU Hôpital de la Timone, Marseille, France., Planchard D; Gustave Roussy, Villejuif, France., Hong Q; Zhongshan Hospital, Fudan University, Shanghai, China., Mazieres J; CHU de Toulouse-Hôpital Larrey, Toulouse, France., Felip E; Vall d'Hebron Institut d'Oncologia, Madrid, Spain., Li X; The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Hu Y; Beijing Chest Hospital, Capital Medical University, Beijing, China., Fang J; Beijing Cancer Hospital, Beijing, China., Bazhenova L; University of California, San Diego (UCSD)-Moores Cancer Center, San Diego, CA., Ghiringhelli F; Centre Georges François Leclerc, Dijon, France., Cobo Dols MA; Hospital Regional Universitario de Málaga, Madrid, Spain., Rodriguez LP; Hospital Universitario 12 de Octubre, Madrid, Spain., Bearz A; CRO Aviano, National Cancer Institute, IRCCS, Aviano, Italy., Pellini B; H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL., Kim YJ; Seoul National University Bundang Hospital, Gyeonggi-do, South Korea., Bosch-Barrera J; Fundacio Privada-Institut d'Investigacio Biomedica de Girona Dr Josep Trueta, Girona, Spain., Shim BY; The Catholic University of Korea, St Vincent's Hospital, Gyeonggi-do, South Korea., Luo YH; Taipei Veterans General Hospital, Taipei, Taiwan., Tiseo M; Azienda Ospedaliero-Universitaria di Parma, Parma, Italy., Yang TY; Taichung Veterans General Hospital, Taichung, Taiwan., Carcereny E; Institut Catala d'Oncologia Badalona-Hospital Germans Trias i Pujol, Madrid, Spain., Memmott RM; The Ohio State University Research Foundation, Columbus, OH., Zalcman G; Hôpital Bichat-Claude-Bernard, Paris, France., de Castro Carpeno J; Hospital Universitario La Paz, Madrid, Spain., Di Noia V; IRCCS Regina Elena National Cancer Institute, Rome, Italy., Parra HS; Azienda Ospedaliero-Universitaria 'Policlinico-Vittorio Emanuele', Catania, Italy., Streich G; Centro Medico Austral OMI, Buenos Aires, Argentina., Lee DH; Asan Medical Center, Seoul, South Korea., Shum E; Laura and Isaac Perlmutter Cancer Center, New York, NY., Han JY; National Cancer Center, Gyeonggi-do, South Korea., Jaime JC; Hospital Universitario de Jerez de la Frontera, Jerez de la Frontera, Spain., Brungs D; Southern Medical Day Care Centre, Wollongong, Australia., John T; Peter MacCallum Cancer Centre, Melbourne, Australia., D'Arcangelo M; AUSL Romagna-Ospedale S.M delle Croci, Ravenna, Italy., Joaquin AB; Hospital de la Santa Creu i Sant Pau, Barcelona, Spain., Liu G; Princess Margaret Cancer Center, Toronto, Canada., Antonuzzo L; Azienda Ospedaliero-Universitaria Careggi, Florence, Italy., Hinojal GF; Clínica Universidad de Navarra-Madrid, Madrid, Spain., Le X; MD Anderson Cancer Center, Houston, TX., Zheng L; Dizal Pharmaceuticals, Shanghai, China., Jänne PA; Dana-Farber Cancer Institute, Boston, MA.
Corporate Authors: WU-KONG1B
Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2025 Oct 10; Vol. 43 (29), pp. 3198-3208. Date of Electronic Publication: 2025 Sep 09.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Clinical Trial, Phase II; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Phase II Dose-Randomized Study of Sunvozertinib in Platinum-Pretreated Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor Exon 20 Insertion Mutations (WU-KONG1B).
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