Structure-guided loop grafting improves expression and stability of influenza neuraminidase for vaccine development.
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| Title: | Structure-guided loop grafting improves expression and stability of influenza neuraminidase for vaccine development. |
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| Authors: | Rijal P; Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom., Wei L; Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom., Paesen GC; Division of Structural Biology, Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Stuart DI; Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Division of Structural Biology, Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Haworth M; Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom., Huang KA; Graduate Institute of Immunology and Department of Paediatrics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.; Genomics Research Center, Academia Sinica, Taipei, Taiwan., Bowden TA; Division of Structural Biology, Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Townsend ARM; Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom. |
| Source: | ELife [Elife] 2025 Sep 09; Vol. 14. Date of Electronic Publication: 2025 Sep 09. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40924000 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Structure-guided loop grafting improves expression and stability of influenza neuraminidase for vaccine development. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Rijal+P%22">Rijal P</searchLink>; Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Wei+L%22">Wei L</searchLink>; Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Paesen+GC%22">Paesen GC</searchLink>; Division of Structural Biology, Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Stuart+DI%22">Stuart DI</searchLink>; Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Division of Structural Biology, Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Haworth+M%22">Haworth M</searchLink>; Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Huang+KA%22">Huang KA</searchLink>; Graduate Institute of Immunology and Department of Paediatrics, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.; Genomics Research Center, Academia Sinica, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Bowden+TA%22">Bowden TA</searchLink>; Division of Structural Biology, Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Townsend+ARM%22">Townsend ARM</searchLink>; Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101579614%22">ELife</searchLink> [Elife] 2025 Sep 09; Vol. 14. <i>Date of Electronic Publication: </i>2025 Sep 09. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22eLife+Sciences+Publications%2C+Ltd%22">eLife Sciences Publications, Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101579614 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2050-084X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222050084X%22">2050084X </searchLink><i>NLM ISO Abbreviation: </i>Elife <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40924000 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.7554/eLife.105317 Languages: – Code: eng Text: English Titles: – TitleFull: Structure-guided loop grafting improves expression and stability of influenza neuraminidase for vaccine development. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Rijal P – PersonEntity: Name: NameFull: Wei L – PersonEntity: Name: NameFull: Paesen GC – PersonEntity: Name: NameFull: Stuart DI – PersonEntity: Name: NameFull: Haworth M – PersonEntity: Name: NameFull: Huang KA – PersonEntity: Name: NameFull: Bowden TA – PersonEntity: Name: NameFull: Townsend ARM IsPartOfRelationships: – BibEntity: Dates: – D: 09 M: 09 Text: 2025 Sep 09 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2050-084X Numbering: – Type: volume Value: 14 Titles: – TitleFull: ELife Type: main |
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