Efficacy and in vitro activity of gepotidacin against bacterial uropathogens, including drug-resistant phenotypes, in females with uncomplicated urinary tract infections: results from two global, pivotal, phase 3 trials (EAGLE-2 and EAGLE-3).
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| Title: | Efficacy and in vitro activity of gepotidacin against bacterial uropathogens, including drug-resistant phenotypes, in females with uncomplicated urinary tract infections: results from two global, pivotal, phase 3 trials (EAGLE-2 and EAGLE-3). |
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| Authors: | Scangarella-Oman NE; GSK, Collegeville, Pennsylvania, USA., Butler DL; GSK, Collegeville, Pennsylvania, USA., Breton J; GSK, Collegeville, Pennsylvania, USA., Brown D; GSK, Collegeville, Pennsylvania, USA., Kasapidis C; GSK, Collegeville, Pennsylvania, USA., Millns H; GSK, Stevenage, Hertfordshire, United Kingdom., Huang C; GSK, Collegeville, Pennsylvania, USA., Perry CR; GSK, Collegeville, Pennsylvania, USA., Sheets AJ; GSK, Collegeville, Pennsylvania, USA., Dennison J; GSK, London, United Kingdom., Janmohamed S; GSK, London, United Kingdom. |
| Source: | Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2025 Oct; Vol. 69 (10), pp. e0164024. Date of Electronic Publication: 2025 Sep 09. |
| Publication Type: | Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial |
| Journal Info: | Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40924001 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Efficacy and in vitro activity of gepotidacin against bacterial uropathogens, including drug-resistant phenotypes, in females with uncomplicated urinary tract infections: results from two global, pivotal, phase 3 trials (EAGLE-2 and EAGLE-3). – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Scangarella-Oman+NE%22">Scangarella-Oman NE</searchLink>; GSK, Collegeville, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Butler+DL%22">Butler DL</searchLink>; GSK, Collegeville, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Breton+J%22">Breton J</searchLink>; GSK, Collegeville, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Brown+D%22">Brown D</searchLink>; GSK, Collegeville, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Kasapidis+C%22">Kasapidis C</searchLink>; GSK, Collegeville, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Millns+H%22">Millns H</searchLink>; GSK, Stevenage, Hertfordshire, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Huang+C%22">Huang C</searchLink>; GSK, Collegeville, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Perry+CR%22">Perry CR</searchLink>; GSK, Collegeville, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Sheets+AJ%22">Sheets AJ</searchLink>; GSK, Collegeville, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Dennison+J%22">Dennison J</searchLink>; GSK, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Janmohamed+S%22">Janmohamed S</searchLink>; GSK, London, United Kingdom. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220315061%22">Antimicrobial agents and chemotherapy</searchLink> [Antimicrob Agents Chemother] 2025 Oct; Vol. 69 (10), pp. e0164024. <i>Date of Electronic Publication: </i>2025 Sep 09. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Microbiology%22">American Society for Microbiology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0315061 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1098-6596 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200664804%22">00664804 </searchLink><i>NLM ISO Abbreviation: </i>Antimicrob Agents Chemother <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40924001 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1128/aac.01640-24 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e0164024 Titles: – TitleFull: Efficacy and in vitro activity of gepotidacin against bacterial uropathogens, including drug-resistant phenotypes, in females with uncomplicated urinary tract infections: results from two global, pivotal, phase 3 trials (EAGLE-2 and EAGLE-3). Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Scangarella-Oman NE – PersonEntity: Name: NameFull: Butler DL – PersonEntity: Name: NameFull: Breton J – PersonEntity: Name: NameFull: Brown D – PersonEntity: Name: NameFull: Kasapidis C – PersonEntity: Name: NameFull: Millns H – PersonEntity: Name: NameFull: Huang C – PersonEntity: Name: NameFull: Perry CR – PersonEntity: Name: NameFull: Sheets AJ – PersonEntity: Name: NameFull: Dennison J – PersonEntity: Name: NameFull: Janmohamed S IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: 2025 Oct Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1098-6596 Numbering: – Type: volume Value: 69 – Type: issue Value: 10 Titles: – TitleFull: Antimicrobial agents and chemotherapy Type: main |
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