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Cathepsin Z is a conserved susceptibility factor underlying tuberculosis severity.

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Title: Cathepsin Z is a conserved susceptibility factor underlying tuberculosis severity.
Authors: Meade RK; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.; University Program in Genetics and Genomics, Duke University, Durham, North Carolina, United States of America., Adefisayo OO; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America., Gontijo MTP; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America., Harris SJ; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America., Pyle CJ; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America., Wilburn KM; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America., Ecker AMV; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America., Hughes EJ; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.; University Program in Genetics and Genomics, Duke University, Durham, North Carolina, United States of America., Garcia PD; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America., Ivie J; Department of Medicine, University of Washington, Seattle, Washington, United States of America., McHenry ML; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, Ohio, United States of America., Benchek PH; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, Ohio, United States of America., Mayanja-Kizza H; Uganda-CWRU Research Collaboration and Department of Medicine, School of Medicine, Makerere University, Kampala, Uganda., Neff JL; Department of Pathology, Duke University, Durham, North Carolina, United States of America., Ko DC; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.; University Program in Genetics and Genomics, Duke University, Durham, North Carolina, United States of America., Stout JE; Division of Infectious Disease and International Health, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America., Stein CM; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, Ohio, United States of America.; Department of Medicine, Case Western Reserve University, Cleveland, Ohio, United States of America., Hawn TR; Department of Medicine, University of Washington, Seattle, Washington, United States of America., Tobin DM; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.; University Program in Genetics and Genomics, Duke University, Durham, North Carolina, United States of America.; Department of Integrative Immunobiology, Duke University, Durham, North Carolina, United States of America., Smith CM; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.; University Program in Genetics and Genomics, Duke University, Durham, North Carolina, United States of America.
Source: PLoS biology [PLoS Biol] 2025 Sep 09; Vol. 23 (9), pp. e3003377. Date of Electronic Publication: 2025 Sep 09 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Meade+RK%22">Meade RK</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.; University Program in Genetics and Genomics, Duke University, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Adefisayo+OO%22">Adefisayo OO</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Gontijo+MTP%22">Gontijo MTP</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Harris+SJ%22">Harris SJ</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Pyle+CJ%22">Pyle CJ</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Wilburn+KM%22">Wilburn KM</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Ecker+AMV%22">Ecker AMV</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Hughes+EJ%22">Hughes EJ</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.; University Program in Genetics and Genomics, Duke University, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Garcia+PD%22">Garcia PD</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Ivie+J%22">Ivie J</searchLink>; Department of Medicine, University of Washington, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22McHenry+ML%22">McHenry ML</searchLink>; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, Ohio, United States of America.<br /><searchLink fieldCode="AU" term="%22Benchek+PH%22">Benchek PH</searchLink>; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, Ohio, United States of America.<br /><searchLink fieldCode="AU" term="%22Mayanja-Kizza+H%22">Mayanja-Kizza H</searchLink>; Uganda-CWRU Research Collaboration and Department of Medicine, School of Medicine, Makerere University, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Neff+JL%22">Neff JL</searchLink>; Department of Pathology, Duke University, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Ko+DC%22">Ko DC</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.; University Program in Genetics and Genomics, Duke University, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Stout+JE%22">Stout JE</searchLink>; Division of Infectious Disease and International Health, Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Stein+CM%22">Stein CM</searchLink>; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, Ohio, United States of America.; Department of Medicine, Case Western Reserve University, Cleveland, Ohio, United States of America.<br /><searchLink fieldCode="AU" term="%22Hawn+TR%22">Hawn TR</searchLink>; Department of Medicine, University of Washington, Seattle, Washington, United States of America.<br /><searchLink fieldCode="AU" term="%22Tobin+DM%22">Tobin DM</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.; University Program in Genetics and Genomics, Duke University, Durham, North Carolina, United States of America.; Department of Integrative Immunobiology, Duke University, Durham, North Carolina, United States of America.<br /><searchLink fieldCode="AU" term="%22Smith+CM%22">Smith CM</searchLink>; Department of Molecular Genetics and Microbiology, Duke University, Durham, North Carolina, United States of America.; University Program in Genetics and Genomics, Duke University, Durham, North Carolina, United States of America.
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  Data: <searchLink fieldCode="JN" term="%22101183755%22">PLoS biology</searchLink> [PLoS Biol] 2025 Sep 09; Vol. 23 (9), pp. e3003377. <i>Date of Electronic Publication: </i>2025 Sep 09 (<i>Print Publication: </i>2025).
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