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The Influence of Single-Stranded or Double-Stranded DNA Tags on Ligand Binding Affinity in DNA-Encoded Libraries.

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Title: The Influence of Single-Stranded or Double-Stranded DNA Tags on Ligand Binding Affinity in DNA-Encoded Libraries.
Authors: Bittner P; Laboratory of Organic Chemistry, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland., Gloger A; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland., Harrison JA; Laboratory of Organic Chemistry, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland., Pruška A; Laboratory of Organic Chemistry, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland., Keller M; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland., Oehler S; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland., Lessing A; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland., Zhang Q; WuXi AppTec, Am Klopferspitz 19a, 82152 Martinsried, Germany., Ma Z; WuXi AppTec, Am Klopferspitz 19a, 82152 Martinsried, Germany., Su W; WuXi AppTec, Am Klopferspitz 19a, 82152 Martinsried, Germany., Satz AL; WuXi AppTec, Am Klopferspitz 19a, 82152 Martinsried, Germany., Kuai L; WuXi AppTec, Am Klopferspitz 19a, 82152 Martinsried, Germany., Scheuermann J; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland., Zenobi R; Laboratory of Organic Chemistry, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland.
Source: Analytical chemistry [Anal Chem] 2025 Sep 23; Vol. 97 (37), pp. 20412-20421. Date of Electronic Publication: 2025 Sep 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6882 (Electronic) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: MEDLINE
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  Data: The Influence of Single-Stranded or Double-Stranded DNA Tags on Ligand Binding Affinity in DNA-Encoded Libraries.
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  Data: <searchLink fieldCode="JN" term="%220370536%22">Analytical chemistry</searchLink> [Anal Chem] 2025 Sep 23; Vol. 97 (37), pp. 20412-20421. <i>Date of Electronic Publication: </i>2025 Sep 09.
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