The Influence of Single-Stranded or Double-Stranded DNA Tags on Ligand Binding Affinity in DNA-Encoded Libraries.
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| Title: | The Influence of Single-Stranded or Double-Stranded DNA Tags on Ligand Binding Affinity in DNA-Encoded Libraries. |
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| Authors: | Bittner P; Laboratory of Organic Chemistry, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland., Gloger A; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland., Harrison JA; Laboratory of Organic Chemistry, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland., Pruška A; Laboratory of Organic Chemistry, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland., Keller M; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland., Oehler S; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland., Lessing A; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland., Zhang Q; WuXi AppTec, Am Klopferspitz 19a, 82152 Martinsried, Germany., Ma Z; WuXi AppTec, Am Klopferspitz 19a, 82152 Martinsried, Germany., Su W; WuXi AppTec, Am Klopferspitz 19a, 82152 Martinsried, Germany., Satz AL; WuXi AppTec, Am Klopferspitz 19a, 82152 Martinsried, Germany., Kuai L; WuXi AppTec, Am Klopferspitz 19a, 82152 Martinsried, Germany., Scheuermann J; Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland., Zenobi R; Laboratory of Organic Chemistry, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland. |
| Source: | Analytical chemistry [Anal Chem] 2025 Sep 23; Vol. 97 (37), pp. 20412-20421. Date of Electronic Publication: 2025 Sep 09. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6882 (Electronic) Linking ISSN: 00032700 NLM ISO Abbreviation: Anal Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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