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Intestinal taurine acts as a novel immunometabolic modulator of IBD by degrading redundant mitochondrial RNA.

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Title: Intestinal taurine acts as a novel immunometabolic modulator of IBD by degrading redundant mitochondrial RNA.
Authors: Wu LX; Department of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou, China., Xie JH; Center for Neuroimmunology and Health Longevity, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; The MOE Key Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang, China., Li JY; The MOE Key Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang, China., Li WP; Center for Neuroimmunology and Health Longevity, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Mao XT; Center for Neuroimmunology and Health Longevity, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Huang LJ; Department of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Biotherapy, Hangzhou, Zhejiang, China., Chen HT; Department of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou, China., Zhong JY; Department of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou, China., Lin LM; Center for Neuroimmunology and Health Longevity, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Su S; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China., Li YY; School of Life, Beijing Institute of Technology, Zhuhai Campus, Zhuhai, China. 103200067@seu.edu.cn., Cao Q; Department of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou, China. caoq@zju.edu.cn.; Zhejiang Key Laboratory of Biotherapy, Hangzhou, Zhejiang, China. caoq@zju.edu.cn., Jin J; Department of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou, China. jjin4@zju.edu.cn.; Center for Neuroimmunology and Health Longevity, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. jjin4@zju.edu.cn.; The MOE Key Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang, China. jjin4@zju.edu.cn.; Zhejiang Key Laboratory of Biotherapy, Hangzhou, Zhejiang, China. jjin4@zju.edu.cn.
Source: Cellular & molecular immunology [Cell Mol Immunol] 2025 Nov; Vol. 22 (11), pp. 1398-1413. Date of Electronic Publication: 2025 Sep 08.
Publication Type: Journal Article
Journal Info: Publisher: Chinese Society of Immunology Country of Publication: China NLM ID: 101242872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2042-0226 (Electronic) Linking ISSN: 16727681 NLM ISO Abbreviation: Cell Mol Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Intestinal taurine acts as a novel immunometabolic modulator of IBD by degrading redundant mitochondrial RNA.
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  Data: <searchLink fieldCode="AU" term="%22Wu+LX%22">Wu LX</searchLink>; Department of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Xie+JH%22">Xie JH</searchLink>; Center for Neuroimmunology and Health Longevity, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.; The MOE Key Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Li+JY%22">Li JY</searchLink>; The MOE Key Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Li+WP%22">Li WP</searchLink>; Center for Neuroimmunology and Health Longevity, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Mao+XT%22">Mao XT</searchLink>; Center for Neuroimmunology and Health Longevity, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Huang+LJ%22">Huang LJ</searchLink>; Department of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou, China.; Zhejiang Key Laboratory of Biotherapy, Hangzhou, Zhejiang, China.<br /><searchLink fieldCode="AU" term="%22Chen+HT%22">Chen HT</searchLink>; Department of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhong+JY%22">Zhong JY</searchLink>; Department of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Lin+LM%22">Lin LM</searchLink>; Center for Neuroimmunology and Health Longevity, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Su+S%22">Su S</searchLink>; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+YY%22">Li YY</searchLink>; School of Life, Beijing Institute of Technology, Zhuhai Campus, Zhuhai, China. 103200067@seu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Cao+Q%22">Cao Q</searchLink>; Department of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou, China. caoq@zju.edu.cn.; Zhejiang Key Laboratory of Biotherapy, Hangzhou, Zhejiang, China. caoq@zju.edu.cn.<br /><searchLink fieldCode="AU" term="%22Jin+J%22">Jin J</searchLink>; Department of Gastroenterology, Sir Run Run Shaw Hospital, College of Medicine Zhejiang University, Hangzhou, China. jjin4@zju.edu.cn.; Center for Neuroimmunology and Health Longevity, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. jjin4@zju.edu.cn.; The MOE Key Laboratory of Biosystems Homeostasis & Protection, Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, Zhejiang, China. jjin4@zju.edu.cn.; Zhejiang Key Laboratory of Biotherapy, Hangzhou, Zhejiang, China. jjin4@zju.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101242872%22">Cellular & molecular immunology</searchLink> [Cell Mol Immunol] 2025 Nov; Vol. 22 (11), pp. 1398-1413. <i>Date of Electronic Publication: </i>2025 Sep 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Chinese+Society+of+Immunology%22">Chinese Society of Immunology </searchLink><i>Country of Publication: </i>China <i>NLM ID: </i>101242872 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2042-0226 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216727681%22">16727681 </searchLink><i>NLM ISO Abbreviation: </i>Cell Mol Immunol <i>Subsets: </i>MEDLINE
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              Text: 2025 Nov
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