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Conserved multiepitopes in Plasmodium falciparum STEVORs enable rational design of a fusion antigen vaccine construct with broad immunogenicity.

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Title: Conserved multiepitopes in Plasmodium falciparum STEVORs enable rational design of a fusion antigen vaccine construct with broad immunogenicity.
Authors: Sun ZS; School of Global Health, Chinese Centre for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, People's Republic of China.; National Health Commission of the People's Republic of China (NHC) Key Laboratory of Parasite and Vector Biology, Shanghai, People's Republic of China.; World Health Organization (WHO) Collaborating Center for Tropical Diseases, Shanghai, People's Republic of China.; National Center for International Research on Tropical Diseases, Shanghai, People's Republic of China., Yin JX; School of Global Health, Chinese Centre for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China., Zhao HQ; School of Global Health, Chinese Centre for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China., Zhu YS; School of Global Health, Chinese Centre for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China., Chen SB; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, People's Republic of China.; National Health Commission of the People's Republic of China (NHC) Key Laboratory of Parasite and Vector Biology, Shanghai, People's Republic of China.; World Health Organization (WHO) Collaborating Center for Tropical Diseases, Shanghai, People's Republic of China.; National Center for International Research on Tropical Diseases, Shanghai, People's Republic of China., Shen HM; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, People's Republic of China.; National Health Commission of the People's Republic of China (NHC) Key Laboratory of Parasite and Vector Biology, Shanghai, People's Republic of China.; World Health Organization (WHO) Collaborating Center for Tropical Diseases, Shanghai, People's Republic of China.; National Center for International Research on Tropical Diseases, Shanghai, People's Republic of China., Xu B; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, People's Republic of China.; National Health Commission of the People's Republic of China (NHC) Key Laboratory of Parasite and Vector Biology, Shanghai, People's Republic of China.; World Health Organization (WHO) Collaborating Center for Tropical Diseases, Shanghai, People's Republic of China.; National Center for International Research on Tropical Diseases, Shanghai, People's Republic of China., Zhou XN; School of Global Health, Chinese Centre for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China., Wang TY; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, People's Republic of China.; National Health Commission of the People's Republic of China (NHC) Key Laboratory of Parasite and Vector Biology, Shanghai, People's Republic of China.; World Health Organization (WHO) Collaborating Center for Tropical Diseases, Shanghai, People's Republic of China.; National Center for International Research on Tropical Diseases, Shanghai, People's Republic of China., Yang WX; Hainan Tropical Diseases Research Center (Hainan Sub-Center, Chinese Center for Tropical Diseases Research), Haikou, People's Republic of China., Duan YW; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, People's Republic of China.; National Health Commission of the People's Republic of China (NHC) Key Laboratory of Parasite and Vector Biology, Shanghai, People's Republic of China.; World Health Organization (WHO) Collaborating Center for Tropical Diseases, Shanghai, People's Republic of China.; National Center for International Research on Tropical Diseases, Shanghai, People's Republic of China., Chen JH; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, People's Republic of China.; National Health Commission of the People's Republic of China (NHC) Key Laboratory of Parasite and Vector Biology, Shanghai, People's Republic of China.; World Health Organization (WHO) Collaborating Center for Tropical Diseases, Shanghai, People's Republic of China.; National Center for International Research on Tropical Diseases, Shanghai, People's Republic of China.; Hainan Tropical Diseases Research Center (Hainan Sub-Center, Chinese Center for Tropical Diseases Research), Haikou, People's Republic of China., Kassegne K; School of Global Health, Chinese Centre for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Source: Emerging microbes & infections [Emerg Microbes Infect] 2025 Dec; Vol. 14 (1), pp. 2552783. Date of Electronic Publication: 2025 Sep 10.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101594885 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2222-1751 (Electronic) Linking ISSN: 22221751 NLM ISO Abbreviation: Emerg Microbes Infect Subsets: MEDLINE
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  Data: Conserved multiepitopes in Plasmodium falciparum STEVORs enable rational design of a fusion antigen vaccine construct with broad immunogenicity.
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  Data: <searchLink fieldCode="AU" term="%22Sun+ZS%22">Sun ZS</searchLink>; School of Global Health, Chinese Centre for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, People's Republic of China.; National Health Commission of the People's Republic of China (NHC) Key Laboratory of Parasite and Vector Biology, Shanghai, People's Republic of China.; World Health Organization (WHO) Collaborating Center for Tropical Diseases, Shanghai, People's Republic of China.; National Center for International Research on Tropical Diseases, Shanghai, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Yin+JX%22">Yin JX</searchLink>; School of Global Health, Chinese Centre for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhao+HQ%22">Zhao HQ</searchLink>; School of Global Health, Chinese Centre for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhu+YS%22">Zhu YS</searchLink>; School of Global Health, Chinese Centre for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Chen+SB%22">Chen SB</searchLink>; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, People's Republic of China.; National Health Commission of the People's Republic of China (NHC) Key Laboratory of Parasite and Vector Biology, Shanghai, People's Republic of China.; World Health Organization (WHO) Collaborating Center for Tropical Diseases, Shanghai, People's Republic of China.; National Center for International Research on Tropical Diseases, Shanghai, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Shen+HM%22">Shen HM</searchLink>; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, People's Republic of China.; National Health Commission of the People's Republic of China (NHC) Key Laboratory of Parasite and Vector Biology, Shanghai, People's Republic of China.; World Health Organization (WHO) Collaborating Center for Tropical Diseases, Shanghai, People's Republic of China.; National Center for International Research on Tropical Diseases, Shanghai, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xu+B%22">Xu B</searchLink>; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, People's Republic of China.; National Health Commission of the People's Republic of China (NHC) Key Laboratory of Parasite and Vector Biology, Shanghai, People's Republic of China.; World Health Organization (WHO) Collaborating Center for Tropical Diseases, Shanghai, People's Republic of China.; National Center for International Research on Tropical Diseases, Shanghai, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhou+XN%22">Zhou XN</searchLink>; School of Global Health, Chinese Centre for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+TY%22">Wang TY</searchLink>; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, People's Republic of China.; National Health Commission of the People's Republic of China (NHC) Key Laboratory of Parasite and Vector Biology, Shanghai, People's Republic of China.; World Health Organization (WHO) Collaborating Center for Tropical Diseases, Shanghai, People's Republic of China.; National Center for International Research on Tropical Diseases, Shanghai, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Yang+WX%22">Yang WX</searchLink>; Hainan Tropical Diseases Research Center (Hainan Sub-Center, Chinese Center for Tropical Diseases Research), Haikou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Duan+YW%22">Duan YW</searchLink>; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, People's Republic of China.; National Health Commission of the People's Republic of China (NHC) Key Laboratory of Parasite and Vector Biology, Shanghai, People's Republic of China.; World Health Organization (WHO) Collaborating Center for Tropical Diseases, Shanghai, People's Republic of China.; National Center for International Research on Tropical Diseases, Shanghai, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Chen+JH%22">Chen JH</searchLink>; National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), Shanghai, People's Republic of China.; National Health Commission of the People's Republic of China (NHC) Key Laboratory of Parasite and Vector Biology, Shanghai, People's Republic of China.; World Health Organization (WHO) Collaborating Center for Tropical Diseases, Shanghai, People's Republic of China.; National Center for International Research on Tropical Diseases, Shanghai, People's Republic of China.; Hainan Tropical Diseases Research Center (Hainan Sub-Center, Chinese Center for Tropical Diseases Research), Haikou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Kassegne+K%22">Kassegne K</searchLink>; School of Global Health, Chinese Centre for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
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