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A potent NLRP3 inhibitor effective against both MCC950-sensitive and -resistant inflammation.

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Title: A potent NLRP3 inhibitor effective against both MCC950-sensitive and -resistant inflammation.
Authors: Kim W; Department of Biological Sciences, College of Natural Science, Seoul National University, Seoul 08826, South Korea., Kim S; Department of Biological Sciences, College of Natural Science, Seoul National University, Seoul 08826, South Korea., Woo H; Department of Biological Sciences, College of Natural Science, Seoul National University, Seoul 08826, South Korea., Jojare RA; Department of Biotechnology and Bioinformatics, Deogiri College, Dr.Babasaheb Ambedkar Marathwada University, Aurangabad, India., Mall R; Biotechnology Research Center, Technology Innovation Institute, P.O. Box:9639, Abu Dhabi, United Arab Emirates., Nicotra A; CIRI, Centre International de Recherche en Infectiologie, Inserm U1111, CNRS UMR5308, Université Claude Bernard Lyon 1, ENS de Lyon, Lyon, France., Py BF; CIRI, Centre International de Recherche en Infectiologie, Inserm U1111, CNRS UMR5308, Université Claude Bernard Lyon 1, ENS de Lyon, Lyon, France., Ngo C; Division of Immunology and Infectious Diseases, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Man SM; Division of Immunology and Infectious Diseases, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia., Patel CN; Biotechnology Research Center, Technology Innovation Institute, P.O. Box:9639, Abu Dhabi, United Arab Emirates; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA. Electronic address: chiragpatel269@gmail.com., Karki R; Department of Biological Sciences, College of Natural Science, Seoul National University, Seoul 08826, South Korea. Electronic address: rkarki@snu.ac.kr.
Source: Cell chemical biology [Cell Chem Biol] 2025 Sep 18; Vol. 32 (9), pp. 1125-1139.e7. Date of Electronic Publication: 2025 Sep 09.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A potent NLRP3 inhibitor effective against both MCC950-sensitive and -resistant inflammation.
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  Data: <searchLink fieldCode="AU" term="%22Kim+W%22">Kim W</searchLink>; Department of Biological Sciences, College of Natural Science, Seoul National University, Seoul 08826, South Korea.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Department of Biological Sciences, College of Natural Science, Seoul National University, Seoul 08826, South Korea.<br /><searchLink fieldCode="AU" term="%22Woo+H%22">Woo H</searchLink>; Department of Biological Sciences, College of Natural Science, Seoul National University, Seoul 08826, South Korea.<br /><searchLink fieldCode="AU" term="%22Jojare+RA%22">Jojare RA</searchLink>; Department of Biotechnology and Bioinformatics, Deogiri College, Dr.Babasaheb Ambedkar Marathwada University, Aurangabad, India.<br /><searchLink fieldCode="AU" term="%22Mall+R%22">Mall R</searchLink>; Biotechnology Research Center, Technology Innovation Institute, P.O. Box:9639, Abu Dhabi, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Nicotra+A%22">Nicotra A</searchLink>; CIRI, Centre International de Recherche en Infectiologie, Inserm U1111, CNRS UMR5308, Université Claude Bernard Lyon 1, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Py+BF%22">Py BF</searchLink>; CIRI, Centre International de Recherche en Infectiologie, Inserm U1111, CNRS UMR5308, Université Claude Bernard Lyon 1, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Ngo+C%22">Ngo C</searchLink>; Division of Immunology and Infectious Diseases, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia.<br /><searchLink fieldCode="AU" term="%22Man+SM%22">Man SM</searchLink>; Division of Immunology and Infectious Diseases, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia.<br /><searchLink fieldCode="AU" term="%22Patel+CN%22">Patel CN</searchLink>; Biotechnology Research Center, Technology Innovation Institute, P.O. Box:9639, Abu Dhabi, United Arab Emirates; Translational Gerontology Branch, National Institute on Aging, NIH, Baltimore, MD, USA. Electronic address: chiragpatel269@gmail.com.<br /><searchLink fieldCode="AU" term="%22Karki+R%22">Karki R</searchLink>; Department of Biological Sciences, College of Natural Science, Seoul National University, Seoul 08826, South Korea. Electronic address: rkarki@snu.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%22101676030%22">Cell chemical biology</searchLink> [Cell Chem Biol] 2025 Sep 18; Vol. 32 (9), pp. 1125-1139.e7. <i>Date of Electronic Publication: </i>2025 Sep 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101676030 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2451-9448 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224519448%22">24519448 </searchLink><i>NLM ISO Abbreviation: </i>Cell Chem Biol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.chembiol.2025.08.006
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              Text: 2025 Sep 18
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