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High-Calorie Diet Accelerates the Liver Tissue Degeneration and Induces Subcutaneous White-to-Brown Fat Conversion in Mice with a Single-Allele Atp7b Mutation.

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Title: High-Calorie Diet Accelerates the Liver Tissue Degeneration and Induces Subcutaneous White-to-Brown Fat Conversion in Mice with a Single-Allele Atp7b Mutation.
Authors: Abbas Q; Research Center of Advanced Functional Materials and Laser Communication Systems, ADTS Institute, ITMO University, St. Petersburg, Russia., Petrova ES; Laboratory of Experimental Histology and Confocal Microscopy, Research Institute of Experimental Medicine, St. Petersburg, Russia., Tsymbalenko NV; Laboratory of Biochemical Genetics, Research Institute of Experimental Medicine, St. Petersburg, Russia., Al Farroukh M; Research Center of Advanced Functional Materials and Laser Communication Systems, ADTS Institute, ITMO University, St. Petersburg, Russia; Laboratory of Biochemical Genetics, Research Institute of Experimental Medicine, St. Petersburg, Russia; Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Magazenkova DN; Research Center of Advanced Functional Materials and Laser Communication Systems, ADTS Institute, ITMO University, St. Petersburg, Russia; Laboratory of Biochemical Genetics, Research Institute of Experimental Medicine, St. Petersburg, Russia; Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Polishchuk EV; Cell Biology and Disease Mechanisms, Telethon Institute of Genetics and Medicine, Pozzuoli, Naples, Italy., Petruzzelli R; Cell Biology and Disease Mechanisms, Telethon Institute of Genetics and Medicine, Pozzuoli, Naples, Italy., Derkach KV; Laboratory of Molecular Endocrinology and Neurochemistry, Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, St. Petersburg, Russia., Kolos EA; Laboratory of Functional Morphology of Central and Peripheral Nervous System, Research Institute of Experimental Medicine, St. Petersburg, Russia., Klyueva NN; Laboratory of Regulation of Lipid Metabolism, Research Institute of Experimental Medicine, St. Petersburg, Russia., Skvortsov AN; Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Di Sole F; Department of Physiology and Pharmacology, Des Moines University, Des Moines, IA, United States., Shpakov AO; Laboratory of Molecular Endocrinology and Neurochemistry, Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, St. Petersburg, Russia., Denisenko AD; Laboratory of Regulation of Lipid Metabolism, Research Institute of Experimental Medicine, St. Petersburg, Russia., Korzhevskii DE; Laboratory of Functional Morphology of Central and Peripheral Nervous System, Research Institute of Experimental Medicine, St. Petersburg, Russia., Gupta A; Department of Biological Sciences, Indian Institute of Science Education and Research, Kolkata, Mohanpur, West Bengal, India., Polishchuk RS; Cell Biology and Disease Mechanisms, Telethon Institute of Genetics and Medicine, Pozzuoli, Naples, Italy., Puchkova LV; Research Center of Advanced Functional Materials and Laser Communication Systems, ADTS Institute, ITMO University, St. Petersburg, Russia; Laboratory of Biochemical Genetics, Research Institute of Experimental Medicine, St. Petersburg, Russia; Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia., Ilyechova EY; Research Center of Advanced Functional Materials and Laser Communication Systems, ADTS Institute, ITMO University, St. Petersburg, Russia; Laboratory of Biochemical Genetics, Research Institute of Experimental Medicine, St. Petersburg, Russia; Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia. Electronic address: ilichevaey@itmo.ru.
Source: The Journal of nutrition [J Nutr] 2025 Dec; Vol. 155 (12), pp. 4239-4252. Date of Electronic Publication: 2025 Sep 10.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0404243 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1541-6100 (Electronic) Linking ISSN: 00223166 NLM ISO Abbreviation: J Nutr Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High-Calorie Diet Accelerates the Liver Tissue Degeneration and Induces Subcutaneous White-to-Brown Fat Conversion in Mice with a Single-Allele Atp7b Mutation.
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  Data: <searchLink fieldCode="AU" term="%22Abbas+Q%22">Abbas Q</searchLink>; Research Center of Advanced Functional Materials and Laser Communication Systems, ADTS Institute, ITMO University, St. Petersburg, Russia.<br /><searchLink fieldCode="AU" term="%22Petrova+ES%22">Petrova ES</searchLink>; Laboratory of Experimental Histology and Confocal Microscopy, Research Institute of Experimental Medicine, St. Petersburg, Russia.<br /><searchLink fieldCode="AU" term="%22Tsymbalenko+NV%22">Tsymbalenko NV</searchLink>; Laboratory of Biochemical Genetics, Research Institute of Experimental Medicine, St. Petersburg, Russia.<br /><searchLink fieldCode="AU" term="%22Al+Farroukh+M%22">Al Farroukh M</searchLink>; Research Center of Advanced Functional Materials and Laser Communication Systems, ADTS Institute, ITMO University, St. Petersburg, Russia; Laboratory of Biochemical Genetics, Research Institute of Experimental Medicine, St. Petersburg, Russia; Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia.<br /><searchLink fieldCode="AU" term="%22Magazenkova+DN%22">Magazenkova DN</searchLink>; Research Center of Advanced Functional Materials and Laser Communication Systems, ADTS Institute, ITMO University, St. Petersburg, Russia; Laboratory of Biochemical Genetics, Research Institute of Experimental Medicine, St. Petersburg, Russia; Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia.<br /><searchLink fieldCode="AU" term="%22Polishchuk+EV%22">Polishchuk EV</searchLink>; Cell Biology and Disease Mechanisms, Telethon Institute of Genetics and Medicine, Pozzuoli, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Petruzzelli+R%22">Petruzzelli R</searchLink>; Cell Biology and Disease Mechanisms, Telethon Institute of Genetics and Medicine, Pozzuoli, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Derkach+KV%22">Derkach KV</searchLink>; Laboratory of Molecular Endocrinology and Neurochemistry, Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, St. Petersburg, Russia.<br /><searchLink fieldCode="AU" term="%22Kolos+EA%22">Kolos EA</searchLink>; Laboratory of Functional Morphology of Central and Peripheral Nervous System, Research Institute of Experimental Medicine, St. Petersburg, Russia.<br /><searchLink fieldCode="AU" term="%22Klyueva+NN%22">Klyueva NN</searchLink>; Laboratory of Regulation of Lipid Metabolism, Research Institute of Experimental Medicine, St. Petersburg, Russia.<br /><searchLink fieldCode="AU" term="%22Skvortsov+AN%22">Skvortsov AN</searchLink>; Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia.<br /><searchLink fieldCode="AU" term="%22Di+Sole+F%22">Di Sole F</searchLink>; Department of Physiology and Pharmacology, Des Moines University, Des Moines, IA, United States.<br /><searchLink fieldCode="AU" term="%22Shpakov+AO%22">Shpakov AO</searchLink>; Laboratory of Molecular Endocrinology and Neurochemistry, Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, St. Petersburg, Russia.<br /><searchLink fieldCode="AU" term="%22Denisenko+AD%22">Denisenko AD</searchLink>; Laboratory of Regulation of Lipid Metabolism, Research Institute of Experimental Medicine, St. Petersburg, Russia.<br /><searchLink fieldCode="AU" term="%22Korzhevskii+DE%22">Korzhevskii DE</searchLink>; Laboratory of Functional Morphology of Central and Peripheral Nervous System, Research Institute of Experimental Medicine, St. Petersburg, Russia.<br /><searchLink fieldCode="AU" term="%22Gupta+A%22">Gupta A</searchLink>; Department of Biological Sciences, Indian Institute of Science Education and Research, Kolkata, Mohanpur, West Bengal, India.<br /><searchLink fieldCode="AU" term="%22Polishchuk+RS%22">Polishchuk RS</searchLink>; Cell Biology and Disease Mechanisms, Telethon Institute of Genetics and Medicine, Pozzuoli, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Puchkova+LV%22">Puchkova LV</searchLink>; Research Center of Advanced Functional Materials and Laser Communication Systems, ADTS Institute, ITMO University, St. Petersburg, Russia; Laboratory of Biochemical Genetics, Research Institute of Experimental Medicine, St. Petersburg, Russia; Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia.<br /><searchLink fieldCode="AU" term="%22Ilyechova+EY%22">Ilyechova EY</searchLink>; Research Center of Advanced Functional Materials and Laser Communication Systems, ADTS Institute, ITMO University, St. Petersburg, Russia; Laboratory of Biochemical Genetics, Research Institute of Experimental Medicine, St. Petersburg, Russia; Institute of Biomedical Systems and Biotechnology, Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia. Electronic address: ilichevaey@itmo.ru.
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  Data: <searchLink fieldCode="JN" term="%220404243%22">The Journal of nutrition</searchLink> [J Nutr] 2025 Dec; Vol. 155 (12), pp. 4239-4252. <i>Date of Electronic Publication: </i>2025 Sep 10.
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        Value: 10.1016/j.tjnut.2025.09.004
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