Towards model-informed precision dosing of intravenous linezolid: a multicentre external evaluation of pharmacokinetic models in critically ill adults.

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Title: Towards model-informed precision dosing of intravenous linezolid: a multicentre external evaluation of pharmacokinetic models in critically ill adults.
Authors: Starp J; Department of Anaesthesiology, LMU University Hospital, LMU Munich, Germany., Leonhardt A; Department of Clinical Pharmacy, Institute of Pharmacy, University of Hamburg, Germany., Zoller M; Department of Anaesthesiology, LMU University Hospital, LMU Munich, Germany., Scharf C; Department of Anaesthesiology, LMU University Hospital, LMU Munich, Germany., Zander J; Laboratory Dr Brunner, Laboratory Medical Care Center Konstanz GmbH, Constance, Germany., Paal M; Institute of Laboratory Medicine, LMU University Hospital, LMU Munich, Germany., Greppmair S; Department of Anaesthesiology, LMU University Hospital, LMU Munich, Germany., Schatz LM; Department of Anaesthesiology, LMU University Hospital, LMU Munich, Germany., Ermtraud J; Department of Clinical Pharmacy, Institute of Pharmacy, University of Hamburg, Germany., Kunzelmann AK; Department of Anaesthesiology, LMU University Hospital, LMU Munich, Germany., König C; Department of Intensive Care Medicine, University Medical Centre Hamburg-Eppendorf, Germany., Grensemann J; Department of Intensive Care Medicine, University Medical Centre Hamburg-Eppendorf, Germany., Reiter L; School of Pharmacy, Faculty of Medicine and Health, University of Sydney, New South Wales, Australia., Lau C; School of Pharmacy, Faculty of Medicine and Health, University of Sydney, New South Wales, Australia; Department of Pharmacy, St Vincent's Hospital, Darlinghurst, New South Wales, Australia., Marriott D; Department of Clinical Pharmacology and Toxicology, St Vincent's Hospital, Darlinghurst, New South Wales, Australia; Department of Clinical Microbiology and Infectious Diseases, St Vincent's Hospital, Darlinghurst, New South Wales, Australia., Stocker SL; School of Pharmacy, Faculty of Medicine and Health, University of Sydney, New South Wales, Australia; Department of Clinical Pharmacology and Toxicology, St Vincent's Hospital, Darlinghurst, New South Wales, Australia., Wicha SG; Department of Clinical Pharmacy, Institute of Pharmacy, University of Hamburg, Germany., Liebchen U; Department of Anaesthesiology, LMU University Hospital, LMU Munich, Germany. Electronic address: uwe.liebchen@med.uni-muenchen.de.
Corporate Authors: PK/PD Study Group of the European Society of Clinical Microbiology and Infectious Diseases (EPASG)
Source: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2026 Jan; Vol. 32 (1), pp. 80-86. Date of Electronic Publication: 2025 Sep 09.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9516420 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-0691 (Electronic) Linking ISSN: 1198743X NLM ISO Abbreviation: Clin Microbiol Infect Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Towards model-informed precision dosing of intravenous linezolid: a multicentre external evaluation of pharmacokinetic models in critically ill adults.
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  Data: <searchLink fieldCode="AU" term="%22Starp+J%22">Starp J</searchLink>; Department of Anaesthesiology, LMU University Hospital, LMU Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Leonhardt+A%22">Leonhardt A</searchLink>; Department of Clinical Pharmacy, Institute of Pharmacy, University of Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Zoller+M%22">Zoller M</searchLink>; Department of Anaesthesiology, LMU University Hospital, LMU Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Scharf+C%22">Scharf C</searchLink>; Department of Anaesthesiology, LMU University Hospital, LMU Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Zander+J%22">Zander J</searchLink>; Laboratory Dr Brunner, Laboratory Medical Care Center Konstanz GmbH, Constance, Germany.<br /><searchLink fieldCode="AU" term="%22Paal+M%22">Paal M</searchLink>; Institute of Laboratory Medicine, LMU University Hospital, LMU Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Greppmair+S%22">Greppmair S</searchLink>; Department of Anaesthesiology, LMU University Hospital, LMU Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schatz+LM%22">Schatz LM</searchLink>; Department of Anaesthesiology, LMU University Hospital, LMU Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ermtraud+J%22">Ermtraud J</searchLink>; Department of Clinical Pharmacy, Institute of Pharmacy, University of Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kunzelmann+AK%22">Kunzelmann AK</searchLink>; Department of Anaesthesiology, LMU University Hospital, LMU Munich, Germany.<br /><searchLink fieldCode="AU" term="%22König+C%22">König C</searchLink>; Department of Intensive Care Medicine, University Medical Centre Hamburg-Eppendorf, Germany.<br /><searchLink fieldCode="AU" term="%22Grensemann+J%22">Grensemann J</searchLink>; Department of Intensive Care Medicine, University Medical Centre Hamburg-Eppendorf, Germany.<br /><searchLink fieldCode="AU" term="%22Reiter+L%22">Reiter L</searchLink>; School of Pharmacy, Faculty of Medicine and Health, University of Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Lau+C%22">Lau C</searchLink>; School of Pharmacy, Faculty of Medicine and Health, University of Sydney, New South Wales, Australia; Department of Pharmacy, St Vincent's Hospital, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Marriott+D%22">Marriott D</searchLink>; Department of Clinical Pharmacology and Toxicology, St Vincent's Hospital, Darlinghurst, New South Wales, Australia; Department of Clinical Microbiology and Infectious Diseases, St Vincent's Hospital, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Stocker+SL%22">Stocker SL</searchLink>; School of Pharmacy, Faculty of Medicine and Health, University of Sydney, New South Wales, Australia; Department of Clinical Pharmacology and Toxicology, St Vincent's Hospital, Darlinghurst, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Wicha+SG%22">Wicha SG</searchLink>; Department of Clinical Pharmacy, Institute of Pharmacy, University of Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Liebchen+U%22">Liebchen U</searchLink>; Department of Anaesthesiology, LMU University Hospital, LMU Munich, Germany. Electronic address: uwe.liebchen@med.uni-muenchen.de.
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  Data: <searchLink fieldCode="JN" term="%229516420%22">Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases</searchLink> [Clin Microbiol Infect] 2026 Jan; Vol. 32 (1), pp. 80-86. <i>Date of Electronic Publication: </i>2025 Sep 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9516420 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1469-0691 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221198743X%22">1198743X </searchLink><i>NLM ISO Abbreviation: </i>Clin Microbiol Infect <i>Subsets: </i>MEDLINE
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