Live biotherapeutic enterococcus lactis MNC-168 promotes the efficacy of immune checkpoint blockade in cancer therapy by activating STING pathway via bacterial membrane vesicles.

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Title: Live biotherapeutic enterococcus lactis MNC-168 promotes the efficacy of immune checkpoint blockade in cancer therapy by activating STING pathway via bacterial membrane vesicles.
Authors: Xian Y; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Chen Z; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Lan Z; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Zhang C; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Sun H; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China., Liu Z; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Kong P; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Liang Y; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Zhao Y; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Liu SM; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China., Zhou Y; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Gan L; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Li B; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Su X; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Huang B; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Xiao C; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Zhu R; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Zhao G; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Lao C; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Lin CS; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Zhang D; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Jiang X; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.
Source: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2557978. Date of Electronic Publication: 2025 Sep 12.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1949-0984
DOI:10.1080/19490976.2025.2557978