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Live biotherapeutic enterococcus lactis MNC-168 promotes the efficacy of immune checkpoint blockade in cancer therapy by activating STING pathway via bacterial membrane vesicles.

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Title: Live biotherapeutic enterococcus lactis MNC-168 promotes the efficacy of immune checkpoint blockade in cancer therapy by activating STING pathway via bacterial membrane vesicles.
Authors: Xian Y; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Chen Z; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Lan Z; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Zhang C; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Sun H; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China., Liu Z; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Kong P; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Liang Y; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Zhao Y; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Liu SM; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China., Zhou Y; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Gan L; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Li B; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Su X; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Huang B; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Xiao C; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Zhu R; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Zhao G; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Lao C; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Lin CS; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Zhang D; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China., Jiang X; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.
Source: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2557978. Date of Electronic Publication: 2025 Sep 12.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Live biotherapeutic enterococcus lactis MNC-168 promotes the efficacy of immune checkpoint blockade in cancer therapy by activating STING pathway via bacterial membrane vesicles.
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  Data: <searchLink fieldCode="AU" term="%22Xian+Y%22">Xian Y</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Lan+Z%22">Lan Z</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Sun+H%22">Sun H</searchLink>; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Kong+P%22">Kong P</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Liang+Y%22">Liang Y</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zhao+Y%22">Zhao Y</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Liu+SM%22">Liu SM</searchLink>; Guangdong Lung Cancer Institute, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Gan+L%22">Gan L</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Li+B%22">Li B</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Su+X%22">Su X</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Huang+B%22">Huang B</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Xiao+C%22">Xiao C</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zhu+R%22">Zhu R</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zhao+G%22">Zhao G</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Lao+C%22">Lao C</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Lin+CS%22">Lin CS</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zhang+D%22">Zhang D</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Jiang+X%22">Jiang X</searchLink>; Moon (Guangzhou) Biotech Co. Ltd, Guangdong, China.
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  Data: <searchLink fieldCode="JN" term="%22101495343%22">Gut microbes</searchLink> [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2557978. <i>Date of Electronic Publication: </i>2025 Sep 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101495343 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1949-0984 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219490976%22">19490976 </searchLink><i>NLM ISO Abbreviation: </i>Gut Microbes <i>Subsets: </i>MEDLINE
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