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Upper-Airway Microbiome, Mucociliary Function, and Clinical Outcomes in Bronchiectasis: Data from the EMBARC-BRIDGE Study.

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Title: Upper-Airway Microbiome, Mucociliary Function, and Clinical Outcomes in Bronchiectasis: Data from the EMBARC-BRIDGE Study.
Authors: Choi H; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Hallym University Kangnam Sacred Heart Hospital, Seoul, Republic of Korea., Richardson H; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom., Hennayake C; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom., Shuttleworth M; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom., Cant E; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom., Bottier M; Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, National Heart and Lung Institute, Imperial College London, London, United Kingdom., Spinou A; Population Health Sciences, Faculty of Life Sciences and Medicine, King's College London, United Kingdom., Robertson K; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom., Long MB; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom., De Soyza A; Population and Health Science Institute, Newcastle University and National Institute of Health Research Biomedical Research Centre for Ageing, Freeman Hospital, Newcastle, United Kingdom., Ringshausen FC; Department of Respiratory Medicine and Infectious Diseases, Hannover Medical School, Hannover, Germany.; Biomedical Research in End-Stage and Obstructive Lung Disease Hannover, German Center for Lung Research, Hannover, Germany., Goeminne P; Department of Respiratory Disease, AZ Nikolaas, Sint-Niklaas, Belgium., Lorent N; Department of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium.; Department of Chronic Diseases, Metabolism and Aging, BREATHE Laboratory, KU Leuven, Leuven, Belgium., Haworth C; Cambridge Centre for Lung Infection, Royal Papworth Hospital and University of Cambridge, Cambridge, United Kingdom., Altenburg J; Department of Respiratory Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands., Loebinger MR; Royal Brompton and Harefield Hospitals and National Heart and Lung Institute, Imperial College London, London, United Kingdom., Alferes de Lima Headley D; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom., Dicker AJ; Population Health and Genomics, University of Dundee School of Medicine, Dundee, United Kingdom., Blasi F; Department of Pathophysiology and Transplantation, University of Milan, Italy.; Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Shteinberg M; Pulmonology Institute and CF Center, Carmel Medical Center, Haifa, Israel.; B. Rappaport Faculty of Medicine, The Technion, Israel Institute of Technology, Haifa, Israel., Aliberti S; Istituto di Ricovero e Cura a Carattere Scientifico Humanitas Research Hospital, Respiratory Unit, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Polverino E; Servicio de Neumología, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca, Vall d'Hebron Barcelona Hospital Campus, Centro de Investigación Biomédica en Red Respiratory Diseases,Barcelona, Spain; and., Sibila O; Servicio de Neumología, Instituto Clínico de Respiratorio, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Hospital Clínic, University of Barcelona, Centro de Investigación Biomédica en Red Respiratory Diseases,Barcelona, Spain., Shoemark A; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom., Chalmers JD; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom.
Source: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2025 Dec; Vol. 211 (12), pp. 2296-2306.
Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Thoracic Society Country of Publication: England NLM ID: 9421642 Publication Model: Print Cited Medium: Internet ISSN: 1535-4970 (Electronic) Linking ISSN: 1073449X NLM ISO Abbreviation: Am J Respir Crit Care Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Upper-Airway Microbiome, Mucociliary Function, and Clinical Outcomes in Bronchiectasis: Data from the EMBARC-BRIDGE Study.
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  Data: <searchLink fieldCode="AU" term="%22Choi+H%22">Choi H</searchLink>; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Hallym University Kangnam Sacred Heart Hospital, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Richardson+H%22">Richardson H</searchLink>; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hennayake+C%22">Hennayake C</searchLink>; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Shuttleworth+M%22">Shuttleworth M</searchLink>; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Cant+E%22">Cant E</searchLink>; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Bottier+M%22">Bottier M</searchLink>; Royal Brompton Hospital, Guy's and St Thomas' NHS Foundation Trust, National Heart and Lung Institute, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Spinou+A%22">Spinou A</searchLink>; Population Health Sciences, Faculty of Life Sciences and Medicine, King's College London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Robertson+K%22">Robertson K</searchLink>; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Long+MB%22">Long MB</searchLink>; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22De+Soyza+A%22">De Soyza A</searchLink>; Population and Health Science Institute, Newcastle University and National Institute of Health Research Biomedical Research Centre for Ageing, Freeman Hospital, Newcastle, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ringshausen+FC%22">Ringshausen FC</searchLink>; Department of Respiratory Medicine and Infectious Diseases, Hannover Medical School, Hannover, Germany.; Biomedical Research in End-Stage and Obstructive Lung Disease Hannover, German Center for Lung Research, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Goeminne+P%22">Goeminne P</searchLink>; Department of Respiratory Disease, AZ Nikolaas, Sint-Niklaas, Belgium.<br /><searchLink fieldCode="AU" term="%22Lorent+N%22">Lorent N</searchLink>; Department of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium.; Department of Chronic Diseases, Metabolism and Aging, BREATHE Laboratory, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Haworth+C%22">Haworth C</searchLink>; Cambridge Centre for Lung Infection, Royal Papworth Hospital and University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Altenburg+J%22">Altenburg J</searchLink>; Department of Respiratory Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Loebinger+MR%22">Loebinger MR</searchLink>; Royal Brompton and Harefield Hospitals and National Heart and Lung Institute, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Alferes+de+Lima+Headley+D%22">Alferes de Lima Headley D</searchLink>; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Dicker+AJ%22">Dicker AJ</searchLink>; Population Health and Genomics, University of Dundee School of Medicine, Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Blasi+F%22">Blasi F</searchLink>; Department of Pathophysiology and Transplantation, University of Milan, Italy.; Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Shteinberg+M%22">Shteinberg M</searchLink>; Pulmonology Institute and CF Center, Carmel Medical Center, Haifa, Israel.; B. Rappaport Faculty of Medicine, The Technion, Israel Institute of Technology, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Aliberti+S%22">Aliberti S</searchLink>; Istituto di Ricovero e Cura a Carattere Scientifico Humanitas Research Hospital, Respiratory Unit, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Polverino+E%22">Polverino E</searchLink>; Servicio de Neumología, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institut de Recerca, Vall d'Hebron Barcelona Hospital Campus, Centro de Investigación Biomédica en Red Respiratory Diseases,Barcelona, Spain; and.<br /><searchLink fieldCode="AU" term="%22Sibila+O%22">Sibila O</searchLink>; Servicio de Neumología, Instituto Clínico de Respiratorio, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Hospital Clínic, University of Barcelona, Centro de Investigación Biomédica en Red Respiratory Diseases,Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Shoemark+A%22">Shoemark A</searchLink>; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Chalmers+JD%22">Chalmers JD</searchLink>; Division of Respiratory Medicine and Gastroenterology, University of Dundee, Ninewells Hospital and Medical School, Dundee, United Kingdom.
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