Structure-activity relationship studies on 2-thienylidene substituted 3-oxo-2,3-dihydrobenzofuran-7-carboxamides as poly (ADP-ribose) polymerase inhibitors.
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| Title: | Structure-activity relationship studies on 2-thienylidene substituted 3-oxo-2,3-dihydrobenzofuran-7-carboxamides as poly (ADP-ribose) polymerase inhibitors. |
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| Authors: | Salami A; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States., Adiele U; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States., Coate G; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States., Diolaiti M; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, United States., Chen H; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, United States., Lu J; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, United States., Ashworth A; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, United States; Department of Medicine, University of California, San Francisco, California 94158, United States., Patil M; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States., Fleishman JS; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States., Ramaraju A; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States., Patel A; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States., Patel H; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States., Patel K; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States., Murakami M; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, MD 20892, United States., Ambudkar SV; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, MD 20892, United States., Talele TT; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States. Electronic address: talelet@stjohns.edu. |
| Source: | Bioorganic chemistry [Bioorg Chem] 2025 Oct; Vol. 165, pp. 108941. Date of Electronic Publication: 2025 Sep 05. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40945025 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Structure-activity relationship studies on 2-thienylidene substituted 3-oxo-2,3-dihydrobenzofuran-7-carboxamides as poly (ADP-ribose) polymerase inhibitors. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Salami+A%22">Salami A</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States.<br /><searchLink fieldCode="AU" term="%22Adiele+U%22">Adiele U</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States.<br /><searchLink fieldCode="AU" term="%22Coate+G%22">Coate G</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States.<br /><searchLink fieldCode="AU" term="%22Diolaiti+M%22">Diolaiti M</searchLink>; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Lu+J%22">Lu J</searchLink>; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Ashworth+A%22">Ashworth A</searchLink>; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, United States; Department of Medicine, University of California, San Francisco, California 94158, United States.<br /><searchLink fieldCode="AU" term="%22Patil+M%22">Patil M</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States.<br /><searchLink fieldCode="AU" term="%22Fleishman+JS%22">Fleishman JS</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States.<br /><searchLink fieldCode="AU" term="%22Ramaraju+A%22">Ramaraju A</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States.<br /><searchLink fieldCode="AU" term="%22Patel+A%22">Patel A</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States.<br /><searchLink fieldCode="AU" term="%22Patel+H%22">Patel H</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States.<br /><searchLink fieldCode="AU" term="%22Patel+K%22">Patel K</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States.<br /><searchLink fieldCode="AU" term="%22Murakami+M%22">Murakami M</searchLink>; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, MD 20892, United States.<br /><searchLink fieldCode="AU" term="%22Ambudkar+SV%22">Ambudkar SV</searchLink>; Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, MD 20892, United States.<br /><searchLink fieldCode="AU" term="%22Talele+TT%22">Talele TT</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States. Electronic address: talelet@stjohns.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%221303703%22">Bioorganic chemistry</searchLink> [Bioorg Chem] 2025 Oct; Vol. 165, pp. 108941. <i>Date of Electronic Publication: </i>2025 Sep 05. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1303703 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2120 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200452068%22">00452068 </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40945025 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.bioorg.2025.108941 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 108941 Titles: – TitleFull: Structure-activity relationship studies on 2-thienylidene substituted 3-oxo-2,3-dihydrobenzofuran-7-carboxamides as poly (ADP-ribose) polymerase inhibitors. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Salami A – PersonEntity: Name: NameFull: Adiele U – PersonEntity: Name: NameFull: Coate G – PersonEntity: Name: NameFull: Diolaiti M – PersonEntity: Name: NameFull: Chen H – PersonEntity: Name: NameFull: Lu J – PersonEntity: Name: NameFull: Ashworth A – PersonEntity: Name: NameFull: Patil M – PersonEntity: Name: NameFull: Fleishman JS – PersonEntity: Name: NameFull: Ramaraju A – PersonEntity: Name: NameFull: Patel A – PersonEntity: Name: NameFull: Patel H – PersonEntity: Name: NameFull: Patel K – PersonEntity: Name: NameFull: Murakami M – PersonEntity: Name: NameFull: Ambudkar SV – PersonEntity: Name: NameFull: Talele TT IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: 2025 Oct Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1090-2120 Numbering: – Type: volume Value: 165 Titles: – TitleFull: Bioorganic chemistry Type: main |
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