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High rates of acquired resistance to fluoroquinolones, bedaquiline, and linezolid in patients failing treatment against drug-resistant tuberculosis in the Republic of Moldova.

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Title: High rates of acquired resistance to fluoroquinolones, bedaquiline, and linezolid in patients failing treatment against drug-resistant tuberculosis in the Republic of Moldova.
Authors: Chesov D; Clinical Infectious Diseases, Research Center Borstel, Leibniz Lung Center, Borstel, Germany; Clinical Tuberculosis Unit, German Center for Infection Research Deutsches Zentrum für Infektionsforschung (DZIF), Hamburg-Lübeck-Borstel-Riems, Germany; Discipline of Pneumology and Allergology, 'Nicolae Testemitanu' State University of Medicine and Pharmacy, Chisinau, Republic of Moldova. Electronic address: dchesov@fz-borstel.de., Reimann M; Clinical Infectious Diseases, Research Center Borstel, Leibniz Lung Center, Borstel, Germany; Clinical Tuberculosis Unit, German Center for Infection Research Deutsches Zentrum für Infektionsforschung (DZIF), Hamburg-Lübeck-Borstel-Riems, Germany., Mukherjee T; Discipline of Pneumology and Allergology, 'Nicolae Testemitanu' State University of Medicine and Pharmacy, Chisinau, Republic of Moldova., Tewatia K; Discipline of Pneumology and Allergology, 'Nicolae Testemitanu' State University of Medicine and Pharmacy, Chisinau, Republic of Moldova., Konstantynovska O; Department of Infectious Disease and Clinical Immunology, 'V.N. Karazin' Kharkiv National University, Kharkiv, Ukraine; Kharkiv Regional Phthisiopulmonological Center, Kharkiv, Ukraine; Department of Infectious Diseases, Imperial College London, London, United Kingdom., David A; 'Chiril Draganiuc' Pneumology Institute, Chisinau, Republic of Moldova., Rusu D; Discipline of Pneumology and Allergology, 'Nicolae Testemitanu' State University of Medicine and Pharmacy, Chisinau, Republic of Moldova; 'Chiril Draganiuc' Pneumology Institute, Chisinau, Republic of Moldova., Ciobanu N; 'Chiril Draganiuc' Pneumology Institute, Chisinau, Republic of Moldova., Crudu V; 'Chiril Draganiuc' Pneumology Institute, Chisinau, Republic of Moldova., Lange C; Clinical Infectious Diseases, Research Center Borstel, Leibniz Lung Center, Borstel, Germany; Clinical Tuberculosis Unit, German Center for Infection Research Deutsches Zentrum für Infektionsforschung (DZIF), Hamburg-Lübeck-Borstel-Riems, Germany; Respiratory Medicine and International Health, University of Lübeck, Germany; Baylor College of Medicine and Texas Children's Hospital, Global Tuberculosis Program, Houston, TX, USA.
Source: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2026 Jan; Vol. 32 (1), pp. 177-180. Date of Electronic Publication: 2025 Sep 11.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9516420 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-0691 (Electronic) Linking ISSN: 1198743X NLM ISO Abbreviation: Clin Microbiol Infect Subsets: MEDLINE
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  Data: High rates of acquired resistance to fluoroquinolones, bedaquiline, and linezolid in patients failing treatment against drug-resistant tuberculosis in the Republic of Moldova.
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  Data: <searchLink fieldCode="AU" term="%22Chesov+D%22">Chesov D</searchLink>; Clinical Infectious Diseases, Research Center Borstel, Leibniz Lung Center, Borstel, Germany; Clinical Tuberculosis Unit, German Center for Infection Research Deutsches Zentrum für Infektionsforschung (DZIF), Hamburg-Lübeck-Borstel-Riems, Germany; Discipline of Pneumology and Allergology, 'Nicolae Testemitanu' State University of Medicine and Pharmacy, Chisinau, Republic of Moldova. Electronic address: dchesov@fz-borstel.de.<br /><searchLink fieldCode="AU" term="%22Reimann+M%22">Reimann M</searchLink>; Clinical Infectious Diseases, Research Center Borstel, Leibniz Lung Center, Borstel, Germany; Clinical Tuberculosis Unit, German Center for Infection Research Deutsches Zentrum für Infektionsforschung (DZIF), Hamburg-Lübeck-Borstel-Riems, Germany.<br /><searchLink fieldCode="AU" term="%22Mukherjee+T%22">Mukherjee T</searchLink>; Discipline of Pneumology and Allergology, 'Nicolae Testemitanu' State University of Medicine and Pharmacy, Chisinau, Republic of Moldova.<br /><searchLink fieldCode="AU" term="%22Tewatia+K%22">Tewatia K</searchLink>; Discipline of Pneumology and Allergology, 'Nicolae Testemitanu' State University of Medicine and Pharmacy, Chisinau, Republic of Moldova.<br /><searchLink fieldCode="AU" term="%22Konstantynovska+O%22">Konstantynovska O</searchLink>; Department of Infectious Disease and Clinical Immunology, 'V.N. Karazin' Kharkiv National University, Kharkiv, Ukraine; Kharkiv Regional Phthisiopulmonological Center, Kharkiv, Ukraine; Department of Infectious Diseases, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22David+A%22">David A</searchLink>; 'Chiril Draganiuc' Pneumology Institute, Chisinau, Republic of Moldova.<br /><searchLink fieldCode="AU" term="%22Rusu+D%22">Rusu D</searchLink>; Discipline of Pneumology and Allergology, 'Nicolae Testemitanu' State University of Medicine and Pharmacy, Chisinau, Republic of Moldova; 'Chiril Draganiuc' Pneumology Institute, Chisinau, Republic of Moldova.<br /><searchLink fieldCode="AU" term="%22Ciobanu+N%22">Ciobanu N</searchLink>; 'Chiril Draganiuc' Pneumology Institute, Chisinau, Republic of Moldova.<br /><searchLink fieldCode="AU" term="%22Crudu+V%22">Crudu V</searchLink>; 'Chiril Draganiuc' Pneumology Institute, Chisinau, Republic of Moldova.<br /><searchLink fieldCode="AU" term="%22Lange+C%22">Lange C</searchLink>; Clinical Infectious Diseases, Research Center Borstel, Leibniz Lung Center, Borstel, Germany; Clinical Tuberculosis Unit, German Center for Infection Research Deutsches Zentrum für Infektionsforschung (DZIF), Hamburg-Lübeck-Borstel-Riems, Germany; Respiratory Medicine and International Health, University of Lübeck, Germany; Baylor College of Medicine and Texas Children's Hospital, Global Tuberculosis Program, Houston, TX, USA.
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              Text: 2026 Jan
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