Expanding the antiviral arsenal: N-arylated 1,2,4-oxadiazol-5(4H)-ones show high activity against orthopoxviruses.
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| Title: | Expanding the antiviral arsenal: N-arylated 1,2,4-oxadiazol-5(4H)-ones show high activity against orthopoxviruses. |
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| Authors: | Semenov AV; Institute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., Saint Petersburg, 199034, Russian Federation; Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk, 634034, Russian Federation., Baykov SV; Institute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., Saint Petersburg, 199034, Russian Federation. Electronic address: s.baykov@spbu.ru., Soldatova NS; Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk, 634034, Russian Federation. Electronic address: soldatovans@tpu.ru., Geyl KK; Institute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., Saint Petersburg, 199034, Russian Federation., Shetnev AA; Pharmaceutical Technology Transfer Centre, Yaroslavl State Pedagogical University Named After K.D. Ushinsky, 108 Respublikanskaya St., Yaroslavl, 150000, Russian Federation., Boyarskiy VP; Institute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., Saint Petersburg, 199034, Russian Federation., Yusubov MS; Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk, 634034, Russian Federation., Bormotov NI; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation., Serova OA; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation., Shishkina LN; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation., Ovchinnikova AS; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation., Odnoshevsky DA; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation., Pyankov OV; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation., Borisevich SS; Ufa Institute of Chemistry of the Ufa Federal Research Center, 71, October Pr., Ufa, 450074, Russian Federation; Institute of Chemical Technology', Novosibirsk State University, 1, Pirogova str., Novosibirsk, 630090, Russian Federation., Gorohov YV; Ufa Institute of Chemistry of the Ufa Federal Research Center, 71, October Pr., Ufa, 450074, Russian Federation., Nikitin VN; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation., Shcherbakov DN; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrentiev Ave., 9, 630090, Novosibirsk, Russian Federation., Yarovaya OI; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrentiev Ave., 9, 630090, Novosibirsk, Russian Federation. Electronic address: ooo@nioch.nsc.ru., Salakhutdinov NF; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrentiev Ave., 9, 630090, Novosibirsk, Russian Federation., Postnikov PS; Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk, 634034, Russian Federation; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrentiev Ave., 9, 630090, Novosibirsk, Russian Federation. |
| Source: | European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 15; Vol. 300, pp. 118124. Date of Electronic Publication: 2025 Sep 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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