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Genome-wide association analysis of neutrophil granularity identifies CDK6 as a regulator of primary granules.

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Title: Genome-wide association analysis of neutrophil granularity identifies CDK6 as a regulator of primary granules.
Authors: Fleming K; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Burley K; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Ponce-Garcia F; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Akbari P; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Wort's Causeway, Cambridge, UK.; Department of Human Genetics, The Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Naveh C; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Rice C; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Zakrzewski P; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Gibbs W; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Groves S; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Cela D; The Francis Crick Institute, Antimicrobial Defence Laboratory, London, UK., Papayannopoulos V; The Francis Crick Institute, Antimicrobial Defence Laboratory, London, UK., Harbort CJ; Cellular Microbiology, Max Planck Institute for Infection Biology, Chariteplatz 1, Berlin, Germany., Mumford A; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK., Amulic B; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.
Source: IScience [iScience] 2025 Jul 07; Vol. 28 (8), pp. 113072. Date of Electronic Publication: 2025 Jul 07 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
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  Data: Genome-wide association analysis of neutrophil granularity identifies CDK6 as a regulator of primary granules.
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  Data: <searchLink fieldCode="AU" term="%22Fleming+K%22">Fleming K</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Burley+K%22">Burley K</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Ponce-Garcia+F%22">Ponce-Garcia F</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Akbari+P%22">Akbari P</searchLink>; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Wort's Causeway, Cambridge, UK.; Department of Human Genetics, The Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Naveh+C%22">Naveh C</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Rice+C%22">Rice C</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Zakrzewski+P%22">Zakrzewski P</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Gibbs+W%22">Gibbs W</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Groves+S%22">Groves S</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Cela+D%22">Cela D</searchLink>; The Francis Crick Institute, Antimicrobial Defence Laboratory, London, UK.<br /><searchLink fieldCode="AU" term="%22Papayannopoulos+V%22">Papayannopoulos V</searchLink>; The Francis Crick Institute, Antimicrobial Defence Laboratory, London, UK.<br /><searchLink fieldCode="AU" term="%22Harbort+CJ%22">Harbort CJ</searchLink>; Cellular Microbiology, Max Planck Institute for Infection Biology, Chariteplatz 1, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Mumford+A%22">Mumford A</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Amulic+B%22">Amulic B</searchLink>; School of Cellular and Molecular Medicine, University of Bristol, Bristol, UK.
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  Data: <searchLink fieldCode="JN" term="%22101724038%22">IScience</searchLink> [iScience] 2025 Jul 07; Vol. 28 (8), pp. 113072. <i>Date of Electronic Publication: </i>2025 Jul 07 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101724038 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2589-0042 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225890042%22">25890042 </searchLink><i>NLM ISO Abbreviation: </i>iScience <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2025 Jul 07
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