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Five-Year Outcomes from Deep Brain Stimulation of the Subthalamic Nucleus for Parkinson Disease.

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Title: Five-Year Outcomes from Deep Brain Stimulation of the Subthalamic Nucleus for Parkinson Disease.
Authors: Starr PA; Department of Neurosurgery, University of California, San Francisco., Shivacharan RS; Division of Neuromodulation, Boston Scientific, Valencia, California., Goldberg E; Division of Neuromodulation, Boston Scientific, Valencia, California., Tröster AI; Department of Clinical Neuropsychology, Barrow Neurological Institute, Phoenix, Arizona., House PA; Neurosurgical Associates LLC, Murray, Utah., Giroux ML; Movement and Neuroperformance Center of Colorado, Englewood.; Now with Clinical Lead Movement Disorders, Praxis Precision Medicines Inc, Boston, Massachusetts., Hebb AO; Department of Neurological Surgery, Kaiser Permanente, Denver, Colorado., Whiting DM; Department of Neurosurgery, Allegheny Health Network, Pittsburgh, Pennsylvania., Leichliter TA; Department of Neurology, Allegheny Health Network, Pittsburgh, Pennsylvania., Ostrem JL; Department of Neurology, University of California, San Francisco., Metman LV; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois.; Now with Department of Neurology, Northwestern University School of Medicine, Chicago, Illinois., Sani S; Department of Neurological Surgery, Rush University Medical Center, Chicago, Illinois., Karl JA; Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois.; Now with Department of Neurology, Northwestern University School of Medicine, Chicago, Illinois., Siddiqui MS; Department of Neurology, Wake Forest School of Medicine, Winston-Salem, North Carolina., Tatter SB; Department of Neurosurgery, Wake Forest School of Medicine, Winston-Salem, North Carolina., Haq IU; Department of Neurology, Wake Forest School of Medicine, Winston-Salem, North Carolina.; Now with Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida., Machado AG; Center for Neurological Restoration Cleveland Clinic, Cleveland, Ohio., Gostkowski M; Center for Neurological Restoration Cleveland Clinic, Cleveland, Ohio., Tagliati M; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, California., Mamelak AN; Department of Neurosurgery, Cedars-Sinai Medical Center, Los Angeles, California., Okun MS; Department of Neurology, College of Medicine, University of Florida, Gainesville., Foote KD; Department of Neurosurgery, College of Medicine, University of Florida, Gainesville., Moguel-Cobos G; Department of Neurology, Barrow Neurological Institute, Phoenix, Arizona., Ponce FA; Department of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona., Pahwa R; Department of Neurology, University of Kansas Medical Center, Kansas City., Lyons K; Department of Neurology, University of Kansas Medical Center, Kansas City., Buetefisch CM; Department of Neurology, Emory University School of Medicine, Atlanta, Georgia., Gross RE; Department of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia.; Now with Department of Neurosurgery, Rutgers University Robert Wood Johnson Medical School, New Brunswick, New Jersey., Luca CC; Department of Neurology, University of Miami School of Medicine, Miami, Florida., Jagid JR; Department of Neurosurgery, University of Miami School of Medicine, Miami, Florida., Revuelta GJ; Department of Neurology, Medical University of South Carolina, Charleston., Takacs I; Department of Neurosurgery, Medical University of South Carolina, Charleston., Pourfar MH; Department of Neurology, New York University Medical Center, New York City., Mogilner AY; Department of Neurosurgery, New York University Medical Center, New York City., Duker AP; Department of Neurology, University of Cincinnati Medical Center, Cincinnati, Ohio., Mandybur GT; Department of Neurosurgery, University of Cincinnati Medical Center, Cincinnati, Ohio.; Now with Department of Neurosurgery, Lee Health, Fort Myers, Florida., Rosenow JM; Department of Neurosurgery, Northwestern University School of Medicine, Chicago, Illinois., Zadikoff C; Department of Neurology, Northwestern University School of Medicine, Chicago, Illinois., Khandhar SM; Department of Neurology, Kaiser Permanente Medical Center, Sacramento, California., Sedrak M; Department of Neurosurgery and Neuroscience, Kaiser Permanente Medical Center, Redwood City, California., Phibbs FT; Department of Neurology, Vanderbilt University Medical Center, Nashville, Tennessee., Neimat J; Department of Neurosurgery, Vanderbilt University Medical Center, Nashville, Tennessee.; Now with Department of Neurosurgery, University of Louisville School of Medicine, Louisville, Kentucky., Durphy J; Department of Neurology, Albany Medical Center, Albany, New York., Ramirez-Zamora A; Department of Neurology, Albany Medical Center, Albany, New York.; Now with Department of Neurology, Normal Fixel Institute for Neurological Disease, University of Florida, Gainesville., Pilitsis JG; Department of Neurosurgery, Albany Medical Center, Albany, New York.; Now with Department of Neurosurgery, University of Arizona College of Medicine, Tucson., Uitti RJ; Department of Neurology, Mayo Clinic, Jacksonville, Florida., Wharen R; Now with Department of Neurosurgery, University of Louisville School of Medicine, Louisville, Kentucky., Park MC; Department of Neurosurgery, University of Minnesota School of Medicine, Minneapolis., Vitek JL; Department of Neurology, University of Minnesota School of Medicine, Minneapolis.
Corporate Authors: INTREPID Study Group
Source: JAMA neurology [JAMA Neurol] 2025 Nov 01; Vol. 82 (11), pp. 1181-1190.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589536 Publication Model: Print Cited Medium: Internet ISSN: 2168-6157 (Electronic) Linking ISSN: 21686149 NLM ISO Abbreviation: JAMA Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2168-6157
DOI:10.1001/jamaneurol.2025.3373