HLA-A2 CAR/IL-2-CISC engineered Treg display robust in vitro and in vivo antigen-specific regulatory function.
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| Title: | HLA-A2 CAR/IL-2-CISC engineered Treg display robust in vitro and in vivo antigen-specific regulatory function. |
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| Authors: | Tripathi SK; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA., Grimm A; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA., Dahl NP; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA., Honaker Y; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA., Knebusch P; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA., Chen Y; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA., Cook PJ; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA., Rawlings DJ; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA.; Department of Pediatrics, University of Washington, Seattle, WA 98105, USA.; Department of Immunology, University of Washington, Seattle, WA 98109, USA. |
| Source: | Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2025 Aug 14; Vol. 33 (3), pp. 101561. Date of Electronic Publication: 2025 Aug 14 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101624857 Publication Model: eCollection Cited Medium: Print ISSN: 2329-0501 (Print) Linking ISSN: 23290501 NLM ISO Abbreviation: Mol Ther Methods Clin Dev Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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