An engineered IgM antibody targeting CD20 has enhanced complement-dependent cytotoxicity compared with an IgG.
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| Title: | An engineered IgM antibody targeting CD20 has enhanced complement-dependent cytotoxicity compared with an IgG. |
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| Authors: | Hart KC; IGM Biosciences Inc., 325 E Middlefield Rd., Mountain View, CA. Electronic address: hartkk16@gmail.com., Hinton PR; IGM Biosciences Inc., 325 E Middlefield Rd., Mountain View, CA., Manlusoc M; IGM Biosciences Inc., 325 E Middlefield Rd., Mountain View, CA., Carlin KB; IGM Biosciences Inc., 325 E Middlefield Rd., Mountain View, CA., Schneider S; IGM Biosciences Inc., 325 E Middlefield Rd., Mountain View, CA., Kotturi MF; IGM Biosciences Inc., 325 E Middlefield Rd., Mountain View, CA., Baliga R; IGM Biosciences Inc., 325 E Middlefield Rd., Mountain View, CA., Keyt BA; IGM Biosciences Inc., 325 E Middlefield Rd., Mountain View, CA. |
| Source: | Experimental hematology [Exp Hematol] 2025 Dec; Vol. 152, pp. 105250. Date of Electronic Publication: 2025 Sep 14. |
| Publication Type: | Journal Article; Comparative Study |
| Journal Info: | Publisher: Elsevier Science Inc Country of Publication: Netherlands NLM ID: 0402313 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2399 (Electronic) Linking ISSN: 0301472X NLM ISO Abbreviation: Exp Hematol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1873-2399 |
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| DOI: | 10.1016/j.exphem.2025.105250 |
