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A xeno-free red blood cell differentiation formula models sickle cell disease from somatically sourced patient iPSCs.

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Title: A xeno-free red blood cell differentiation formula models sickle cell disease from somatically sourced patient iPSCs.
Authors: Conway AJ; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA., Rosanwo TO; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA., Williamson TE; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA., Landry S; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA., Kinney MA; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA., Clark MA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA., Vo LT; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA., Rowe RG; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA., Marion W; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA., Zhang Y; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA., Mullin NK; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA., Shi M; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA., Archer NM; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA., Heeney MM; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA., Schlaeger TM; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA., Bauer DE; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA., Duraisingh MT; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA., Brugnara C; Department of Laboratory Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA., North TE; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA. Electronic address: Trista.North@childrens.harvard.edu., Daley GQ; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA. Electronic address: George_Daley@childrens.harvard.edu.
Source: Experimental hematology [Exp Hematol] 2025 Dec; Vol. 152, pp. 105264. Date of Electronic Publication: 2025 Sep 14.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Inc Country of Publication: Netherlands NLM ID: 0402313 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2399 (Electronic) Linking ISSN: 0301472X NLM ISO Abbreviation: Exp Hematol Subsets: MEDLINE
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  Data: A xeno-free red blood cell differentiation formula models sickle cell disease from somatically sourced patient iPSCs.
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  Data: <searchLink fieldCode="AU" term="%22Conway+AJ%22">Conway AJ</searchLink>; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Rosanwo+TO%22">Rosanwo TO</searchLink>; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Williamson+TE%22">Williamson TE</searchLink>; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Landry+S%22">Landry S</searchLink>; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Kinney+MA%22">Kinney MA</searchLink>; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Clark+MA%22">Clark MA</searchLink>; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Vo+LT%22">Vo LT</searchLink>; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Rowe+RG%22">Rowe RG</searchLink>; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Marion+W%22">Marion W</searchLink>; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Mullin+NK%22">Mullin NK</searchLink>; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Shi+M%22">Shi M</searchLink>; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Archer+NM%22">Archer NM</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Heeney+MM%22">Heeney MM</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Schlaeger+TM%22">Schlaeger TM</searchLink>; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Bauer+DE%22">Bauer DE</searchLink>; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Duraisingh+MT%22">Duraisingh MT</searchLink>; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Brugnara+C%22">Brugnara C</searchLink>; Department of Laboratory Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22North+TE%22">North TE</searchLink>; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA. Electronic address: Trista.North@childrens.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Daley+GQ%22">Daley GQ</searchLink>; Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA; Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School, Boston, MA. Electronic address: George_Daley@childrens.harvard.edu.
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        Value: 10.1016/j.exphem.2025.105264
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              Text: 2025 Dec
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