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JPI-547, a Dual Inhibitor of PARP/Tankyrase, Shows Antitumor Activity Against Pancreatic Cancers with Homologous Recombination Repair Deficiency or Wnt-Addiction.

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Title: JPI-547, a Dual Inhibitor of PARP/Tankyrase, Shows Antitumor Activity Against Pancreatic Cancers with Homologous Recombination Repair Deficiency or Wnt-Addiction.
Authors: Oh KS; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea., Nam AR; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea., Bang JH; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea., Jeong Y; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea., Choo SY; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea., Kim HJ; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea., Lee SI; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea., Kim JM; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea.; Integrated Major in Innovative Medical Science, Seoul National University Graduate School, Seoul 03080, Korea., Yoon J; Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Korea., Kim TY; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea.; Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Korea., Oh DY; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea.; Integrated Major in Innovative Medical Science, Seoul National University Graduate School, Seoul 03080, Korea.; Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Korea.
Source: International journal of biological sciences [Int J Biol Sci] 2025 Aug 22; Vol. 21 (12), pp. 5460-5475. Date of Electronic Publication: 2025 Aug 22 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Country of Publication: Australia NLM ID: 101235568 Publication Model: eCollection Cited Medium: Internet ISSN: 1449-2288 (Electronic) Linking ISSN: 14492288 NLM ISO Abbreviation: Int J Biol Sci Subsets: MEDLINE
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  Data: JPI-547, a Dual Inhibitor of PARP/Tankyrase, Shows Antitumor Activity Against Pancreatic Cancers with Homologous Recombination Repair Deficiency or Wnt-Addiction.
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  Data: <searchLink fieldCode="AU" term="%22Oh+KS%22">Oh KS</searchLink>; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Nam+AR%22">Nam AR</searchLink>; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Bang+JH%22">Bang JH</searchLink>; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Jeong+Y%22">Jeong Y</searchLink>; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Choo+SY%22">Choo SY</searchLink>; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HJ%22">Kim HJ</searchLink>; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+SI%22">Lee SI</searchLink>; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JM%22">Kim JM</searchLink>; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea.; Integrated Major in Innovative Medical Science, Seoul National University Graduate School, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Yoon+J%22">Yoon J</searchLink>; Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+TY%22">Kim TY</searchLink>; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea.; Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Korea.<br /><searchLink fieldCode="AU" term="%22Oh+DY%22">Oh DY</searchLink>; Cancer Research Institute, Seoul National University College of Medicine, Seoul 03080, Korea.; Integrated Major in Innovative Medical Science, Seoul National University Graduate School, Seoul 03080, Korea.; Department of Internal Medicine, Seoul National University Hospital, Seoul 03080, Korea.
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  Data: <searchLink fieldCode="JN" term="%22101235568%22">International journal of biological sciences</searchLink> [Int J Biol Sci] 2025 Aug 22; Vol. 21 (12), pp. 5460-5475. <i>Date of Electronic Publication: </i>2025 Aug 22 (<i>Print Publication: </i>2025).
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        Value: 10.7150/ijbs.113726
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