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Longitudinal multi-omic signatures of ARDS and sepsis inflammatory phenotypes identify key pathways associated with mortality.

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Title: Longitudinal multi-omic signatures of ARDS and sepsis inflammatory phenotypes identify key pathways associated with mortality.
Authors: Alipanah-Lechner N; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA., Neyton L; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA., Sinha P; Division of Clinical and Translational Research, Department of Anesthesia, Washington University School of Medicine; St. Louis, Missouri, USA., Leroux C; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA., Bardillon K; Cardiovascular Research Institute, University of California San Francisco; USA., Carrillo SA; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA., Chak S; Cardiovascular Research Institute, University of California San Francisco; USA., Chao O; Cardiovascular Research Institute, University of California San Francisco; USA., Hariharan T; Department of Medicine, School of Medicine, University of California San Diego; USA., Henrickson C; Division of Pulmonary and Critical Care, Department of Medicine, Zuckerberg San Francisco General Hospital; California, USA., Kangelaris K; Division of Hospital Medicine, Department of Medicine, University of California San Francisco; USA., Langelier CR; Division of Infectious Disease, Department of Medicine, University of California San Francisco; USA., Lee D; Cardiovascular Research Institute, University of California San Francisco; USA., Lin C; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA., Liu K; Division of Nephrology, Department of Medicine, University of California San Francisco; USA.; Department of Anesthesia, University of California San Francisco; USA., Magee L; Cardiovascular Research Institute, University of California San Francisco; USA., Ringor A; Cardiovascular Research Institute, University of California San Francisco; USA., Sarma A; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA., Schmiege E; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA., Spottiswoode N; Division of Infectious Disease, Department of Medicine, University of California San Francisco; USA., Sullivan K; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA., Weingart MF; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA., Willmore A; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA., Zhuo H; Cardiovascular Research Institute, University of California San Francisco; USA., Rogers AJ; Division of Pulmonary and Critical Care, Department of Medicine, Stanford University; California, USA., Stringer KA; Department of Clinical Pharmacy, College of Pharmacy, University of Michigan; USA.; Division of Pulmonary and Critical Care Medicine, School of Medicine, University of Michigan; USA., Matthay MA; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA.; Department of Anesthesia, University of California San Francisco; USA., Calfee CS; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA.; Department of Anesthesia, University of California San Francisco; USA.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2025 Sep 10. Date of Electronic Publication: 2025 Sep 10.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Longitudinal multi-omic signatures of ARDS and sepsis inflammatory phenotypes identify key pathways associated with mortality.
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  Data: <searchLink fieldCode="AU" term="%22Alipanah-Lechner+N%22">Alipanah-Lechner N</searchLink>; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Neyton+L%22">Neyton L</searchLink>; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Sinha+P%22">Sinha P</searchLink>; Division of Clinical and Translational Research, Department of Anesthesia, Washington University School of Medicine; St. Louis, Missouri, USA.<br /><searchLink fieldCode="AU" term="%22Leroux+C%22">Leroux C</searchLink>; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Bardillon+K%22">Bardillon K</searchLink>; Cardiovascular Research Institute, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Carrillo+SA%22">Carrillo SA</searchLink>; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Chak+S%22">Chak S</searchLink>; Cardiovascular Research Institute, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Chao+O%22">Chao O</searchLink>; Cardiovascular Research Institute, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Hariharan+T%22">Hariharan T</searchLink>; Department of Medicine, School of Medicine, University of California San Diego; USA.<br /><searchLink fieldCode="AU" term="%22Henrickson+C%22">Henrickson C</searchLink>; Division of Pulmonary and Critical Care, Department of Medicine, Zuckerberg San Francisco General Hospital; California, USA.<br /><searchLink fieldCode="AU" term="%22Kangelaris+K%22">Kangelaris K</searchLink>; Division of Hospital Medicine, Department of Medicine, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Langelier+CR%22">Langelier CR</searchLink>; Division of Infectious Disease, Department of Medicine, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Lee+D%22">Lee D</searchLink>; Cardiovascular Research Institute, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Lin+C%22">Lin C</searchLink>; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Liu+K%22">Liu K</searchLink>; Division of Nephrology, Department of Medicine, University of California San Francisco; USA.; Department of Anesthesia, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Magee+L%22">Magee L</searchLink>; Cardiovascular Research Institute, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Ringor+A%22">Ringor A</searchLink>; Cardiovascular Research Institute, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Sarma+A%22">Sarma A</searchLink>; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Schmiege+E%22">Schmiege E</searchLink>; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Spottiswoode+N%22">Spottiswoode N</searchLink>; Division of Infectious Disease, Department of Medicine, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Sullivan+K%22">Sullivan K</searchLink>; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Weingart+MF%22">Weingart MF</searchLink>; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Willmore+A%22">Willmore A</searchLink>; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Zhuo+H%22">Zhuo H</searchLink>; Cardiovascular Research Institute, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Rogers+AJ%22">Rogers AJ</searchLink>; Division of Pulmonary and Critical Care, Department of Medicine, Stanford University; California, USA.<br /><searchLink fieldCode="AU" term="%22Stringer+KA%22">Stringer KA</searchLink>; Department of Clinical Pharmacy, College of Pharmacy, University of Michigan; USA.; Division of Pulmonary and Critical Care Medicine, School of Medicine, University of Michigan; USA.<br /><searchLink fieldCode="AU" term="%22Matthay+MA%22">Matthay MA</searchLink>; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA.; Department of Anesthesia, University of California San Francisco; USA.<br /><searchLink fieldCode="AU" term="%22Calfee+CS%22">Calfee CS</searchLink>; Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, Department of Medicine, University of California San Francisco; USA.; Department of Anesthesia, University of California San Francisco; USA.
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