Fludarabine Lymphodepletion Exposure is Associated with Toxicities after Idecabtagene-Vicleucel in Relapsed/Refractory Multiple Myeloma: Real-World Experience from the US Myeloma Immunotherapy Consortium.

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Title: Fludarabine Lymphodepletion Exposure is Associated with Toxicities after Idecabtagene-Vicleucel in Relapsed/Refractory Multiple Myeloma: Real-World Experience from the US Myeloma Immunotherapy Consortium.
Authors: Sweiss K; University of Illinois at Chicago, Chicago, Illinois. Electronic address: ksweis2@uic.edu., Wagner C; Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah., Anto E; Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah., Greene T; Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah., Sun R; University of Illinois at Chicago, Chicago, Illinois., Gonzalez R; H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Puglianini OC; H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Freeman C; H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Ionescu F; H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Patel K; The University of Texas MD Anderson Cancer Center, Houston, Texas., Ferreri C; The University of Texas MD Anderson Cancer Center, Houston, Texas., Gaballa M; The University of Texas MD Anderson Cancer Center, Houston, Texas., Shune L; The University of Kansas Medical Center, Kansas City, Kansas., McGuirk J; The University of Kansas Medical Center, Kansas City, Kansas., Sidana S; Stanford University, Palo Alto, California., Hovanky V; Stanford University, Palo Alto, California., Khouri J; Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio., Raza S; Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio., Anwer F; Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio., Dima D; Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio., Hashmi H; Medical University of South Carolina, Charleston, South Carolina., Davis J; Medical University of South Carolina, Charleston, South Carolina., Afrough A; Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Hematologic Malignancies and Cellular Therapy Program, Dallas, Texas., Kaur G; Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Hematologic Malignancies and Cellular Therapy Program, Dallas, Texas., Anderson L Jr; Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Hematologic Malignancies and Cellular Therapy Program, Dallas, Texas., Forsberg P; UC Health Blood Disorders and Cell Therapies Center, Aurora, Colorado., Herr M; Roswell Park Comprehensive Cancer Center, Buffalo, New York., Hansen DK; H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida., Hakan Kocoglu M; University of Maryland Marlene and Stewart Greenbaum Comprehensive Cancer Center, Baltimore, Maryland., Sborov D; Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah.
Source: Transplantation and cellular therapy [Transplant Cell Ther] 2025 Dec; Vol. 31 (12), pp. 989-999. Date of Electronic Publication: 2025 Sep 17.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101774629 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-6367 (Electronic) Linking ISSN: 26666367 NLM ISO Abbreviation: Transplant Cell Ther Subsets: MEDLINE
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  Data: Fludarabine Lymphodepletion Exposure is Associated with Toxicities after Idecabtagene-Vicleucel in Relapsed/Refractory Multiple Myeloma: Real-World Experience from the US Myeloma Immunotherapy Consortium.
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  Data: <searchLink fieldCode="AU" term="%22Sweiss+K%22">Sweiss K</searchLink>; University of Illinois at Chicago, Chicago, Illinois. Electronic address: ksweis2@uic.edu.<br /><searchLink fieldCode="AU" term="%22Wagner+C%22">Wagner C</searchLink>; Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah.<br /><searchLink fieldCode="AU" term="%22Anto+E%22">Anto E</searchLink>; Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah.<br /><searchLink fieldCode="AU" term="%22Greene+T%22">Greene T</searchLink>; Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah.<br /><searchLink fieldCode="AU" term="%22Sun+R%22">Sun R</searchLink>; University of Illinois at Chicago, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Gonzalez+R%22">Gonzalez R</searchLink>; H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Puglianini+OC%22">Puglianini OC</searchLink>; H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Freeman+C%22">Freeman C</searchLink>; H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Ionescu+F%22">Ionescu F</searchLink>; H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Patel+K%22">Patel K</searchLink>; The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Ferreri+C%22">Ferreri C</searchLink>; The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Gaballa+M%22">Gaballa M</searchLink>; The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Shune+L%22">Shune L</searchLink>; The University of Kansas Medical Center, Kansas City, Kansas.<br /><searchLink fieldCode="AU" term="%22McGuirk+J%22">McGuirk J</searchLink>; The University of Kansas Medical Center, Kansas City, Kansas.<br /><searchLink fieldCode="AU" term="%22Sidana+S%22">Sidana S</searchLink>; Stanford University, Palo Alto, California.<br /><searchLink fieldCode="AU" term="%22Hovanky+V%22">Hovanky V</searchLink>; Stanford University, Palo Alto, California.<br /><searchLink fieldCode="AU" term="%22Khouri+J%22">Khouri J</searchLink>; Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Raza+S%22">Raza S</searchLink>; Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Anwer+F%22">Anwer F</searchLink>; Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Dima+D%22">Dima D</searchLink>; Cleveland Clinic Taussig Cancer Center, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Hashmi+H%22">Hashmi H</searchLink>; Medical University of South Carolina, Charleston, South Carolina.<br /><searchLink fieldCode="AU" term="%22Davis+J%22">Davis J</searchLink>; Medical University of South Carolina, Charleston, South Carolina.<br /><searchLink fieldCode="AU" term="%22Afrough+A%22">Afrough A</searchLink>; Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Hematologic Malignancies and Cellular Therapy Program, Dallas, Texas.<br /><searchLink fieldCode="AU" term="%22Kaur+G%22">Kaur G</searchLink>; Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Hematologic Malignancies and Cellular Therapy Program, Dallas, Texas.<br /><searchLink fieldCode="AU" term="%22Anderson+L+Jr%22">Anderson L Jr</searchLink>; Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Hematologic Malignancies and Cellular Therapy Program, Dallas, Texas.<br /><searchLink fieldCode="AU" term="%22Forsberg+P%22">Forsberg P</searchLink>; UC Health Blood Disorders and Cell Therapies Center, Aurora, Colorado.<br /><searchLink fieldCode="AU" term="%22Herr+M%22">Herr M</searchLink>; Roswell Park Comprehensive Cancer Center, Buffalo, New York.<br /><searchLink fieldCode="AU" term="%22Hansen+DK%22">Hansen DK</searchLink>; H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Hakan+Kocoglu+M%22">Hakan Kocoglu M</searchLink>; University of Maryland Marlene and Stewart Greenbaum Comprehensive Cancer Center, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Sborov+D%22">Sborov D</searchLink>; Huntsman Cancer Institute at the University of Utah, Salt Lake City, Utah.
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