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Spatial profiling of gene editing by in situ sequencing in mice and macaques.

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Title: Spatial profiling of gene editing by in situ sequencing in mice and macaques.
Authors: Janjuha S; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland. sharan.janjuha@pharma.uzh.ch., Haenggi T; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Chamberlain TC; Acuitas Therapeutics, Vancouver, British Columbia, Canada., Rothgangl T; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Kissling L; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Wilhelm M; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Mathis N; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Boeck D; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Marquart K; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Ioannidi E; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Moon WJ; Acuitas Therapeutics, Vancouver, British Columbia, Canada., Muramatsu H; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Vadovics M; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Pardi N; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Semple SC; Acuitas Therapeutics, Vancouver, British Columbia, Canada., Tam YK; Acuitas Therapeutics, Vancouver, British Columbia, Canada., Schwank G; Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland. schwank@pharma.uzh.ch.
Source: Nature biomedical engineering [Nat Biomed Eng] 2026 May; Vol. 10 (5), pp. 968-979. Date of Electronic Publication: 2025 Sep 19.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 101696896 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2157-846X (Electronic) Linking ISSN: 2157846X NLM ISO Abbreviation: Nat Biomed Eng Subsets: MEDLINE
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