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Impact of patisiran on polyneuropathy of hereditary transthyretin amyloidosis in patients with a V122I or T60A variant: a phase IV multicenter study.

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Title: Impact of patisiran on polyneuropathy of hereditary transthyretin amyloidosis in patients with a V122I or T60A variant: a phase IV multicenter study.
Authors: Hussain Y; Austin Neuromuscular Center, Austin, TX, USA., Malhotra S; Division of Cardiology, Cook County Health and Rush Medical College, Chicago, IL, USA., Sperry BW; Department of Cardiovascular Medicine, Saint Luke's Mid America Heart Institute, Kansas City, MO, USA., Shu F; Department of Neuroscience, Baylor University Medical Center/Baylor Scott and White Health, Dallas, TX, USA., Ananthasubramaniam K; Department of Cardiology, Henry Ford West Bloomfield Hospital, West Bloomfield Township, MI, USA., Desai U; Department of Neurology, Atrium Health Wake Forest University, Charlotte, NC, USA., Egolum U; Northeast Georgia Medical Center, Division of Cardiology, Georgia Heart Institute, Gainesville, GA, USA., Fernandez J; Department of Cardiovascular Services, Morsani College of Medicine, University of South Florida, Tampa, FL, USA., Freimer M; Department of Neurology, Wexner Medical Center, Ohio State University, Columbus, OH, USA., Mauricio E; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA., Quan D; Department of Neurology, University of Colorado Anschutz, Aurora, CO, USA., Small R; Department of Cardiology, Lancaster General Health/Penn Medicine, Lancaster, PA, USA., Capocelli K; Alnylam Pharmaceuticals, Cambridge, MA, USA., Roblin S; Alnylam Pharmaceuticals, Cambridge, MA, USA., Bender S; Alnylam Pharmaceuticals, Cambridge, MA, USA., Jay PY; Alnylam Pharmaceuticals, Cambridge, MA, USA., Yureneva E; Alnylam Pharmaceuticals, Cambridge, MA, USA., Zolty R; Department of Cardiology, University of Nebraska Medical Center, Omaha, NE, USA.
Source: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2537347. Date of Electronic Publication: 2025 Sep 20.
Publication Type: Journal Article; Multicenter Study; Clinical Trial, Phase IV
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Impact of patisiran on polyneuropathy of hereditary transthyretin amyloidosis in patients with a V122I or T60A variant: a phase IV multicenter study.
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  Data: <searchLink fieldCode="AU" term="%22Hussain+Y%22">Hussain Y</searchLink>; Austin Neuromuscular Center, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Malhotra+S%22">Malhotra S</searchLink>; Division of Cardiology, Cook County Health and Rush Medical College, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Sperry+BW%22">Sperry BW</searchLink>; Department of Cardiovascular Medicine, Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.<br /><searchLink fieldCode="AU" term="%22Shu+F%22">Shu F</searchLink>; Department of Neuroscience, Baylor University Medical Center/Baylor Scott and White Health, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ananthasubramaniam+K%22">Ananthasubramaniam K</searchLink>; Department of Cardiology, Henry Ford West Bloomfield Hospital, West Bloomfield Township, MI, USA.<br /><searchLink fieldCode="AU" term="%22Desai+U%22">Desai U</searchLink>; Department of Neurology, Atrium Health Wake Forest University, Charlotte, NC, USA.<br /><searchLink fieldCode="AU" term="%22Egolum+U%22">Egolum U</searchLink>; Northeast Georgia Medical Center, Division of Cardiology, Georgia Heart Institute, Gainesville, GA, USA.<br /><searchLink fieldCode="AU" term="%22Fernandez+J%22">Fernandez J</searchLink>; Department of Cardiovascular Services, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22Freimer+M%22">Freimer M</searchLink>; Department of Neurology, Wexner Medical Center, Ohio State University, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Mauricio+E%22">Mauricio E</searchLink>; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Quan+D%22">Quan D</searchLink>; Department of Neurology, University of Colorado Anschutz, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Small+R%22">Small R</searchLink>; Department of Cardiology, Lancaster General Health/Penn Medicine, Lancaster, PA, USA.<br /><searchLink fieldCode="AU" term="%22Capocelli+K%22">Capocelli K</searchLink>; Alnylam Pharmaceuticals, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Roblin+S%22">Roblin S</searchLink>; Alnylam Pharmaceuticals, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bender+S%22">Bender S</searchLink>; Alnylam Pharmaceuticals, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jay+PY%22">Jay PY</searchLink>; Alnylam Pharmaceuticals, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Yureneva+E%22">Yureneva E</searchLink>; Alnylam Pharmaceuticals, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zolty+R%22">Zolty R</searchLink>; Department of Cardiology, University of Nebraska Medical Center, Omaha, NE, USA.
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  Data: <searchLink fieldCode="JN" term="%228906388%22">Annals of medicine</searchLink> [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2537347. <i>Date of Electronic Publication: </i>2025 Sep 20.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Informa+Healthcare%22">Informa Healthcare </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8906388 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1365-2060 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207853890%22">07853890 </searchLink><i>NLM ISO Abbreviation: </i>Ann Med <i>Subsets: </i>MEDLINE
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