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Association of SGLT2 inhibitors and GLP-1 receptor agonists with the risk of Parkinson's disease in patients with type 2 diabetes: A propensity score-matched cohort study with meta-analysis.

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Title: Association of SGLT2 inhibitors and GLP-1 receptor agonists with the risk of Parkinson's disease in patients with type 2 diabetes: A propensity score-matched cohort study with meta-analysis.
Authors: Yeh JA; School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan., Lin SM; Department of Physical Medicine and Rehabilitation, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan; School of Medicine, Tzu Chi University, Hualien, Taiwan., Liu YC; Department of Emergency Medicine, Chi Mei Medical Center, Tainan, Taiwan; Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan., Hsu JZ; Center for Clinical Epidemiology and Biostatistics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Huang AH; Department of Internal Medicine, University of Connecticut School of Medicine, Farmington, USA., Munir KM; Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA., Peng CC; Division of Endocrinology and Metabolism, Department of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan., Loh CH; School of Medicine, Tzu Chi University, Hualien, Taiwan; Center for Aging and Health, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Huang HK; School of Medicine, Tzu Chi University, Hualien, Taiwan; Center for Clinical Epidemiology and Biostatistics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan; Department of Family Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan. Electronic address: drhkhuang@gmail.com.
Source: Diabetes research and clinical practice [Diabetes Res Clin Pract] 2025 Nov; Vol. 229, pp. 112914. Date of Electronic Publication: 2025 Sep 19.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8508335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8227 (Electronic) Linking ISSN: 01688227 NLM ISO Abbreviation: Diabetes Res Clin Pract Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Association of SGLT2 inhibitors and GLP-1 receptor agonists with the risk of Parkinson's disease in patients with type 2 diabetes: A propensity score-matched cohort study with meta-analysis.
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  Data: <searchLink fieldCode="AU" term="%22Yeh+JA%22">Yeh JA</searchLink>; School of Medicine, College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+SM%22">Lin SM</searchLink>; Department of Physical Medicine and Rehabilitation, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan; School of Medicine, Tzu Chi University, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+YC%22">Liu YC</searchLink>; Department of Emergency Medicine, Chi Mei Medical Center, Tainan, Taiwan; Department of Environmental and Occupational Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+JZ%22">Hsu JZ</searchLink>; Center for Clinical Epidemiology and Biostatistics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+AH%22">Huang AH</searchLink>; Department of Internal Medicine, University of Connecticut School of Medicine, Farmington, USA.<br /><searchLink fieldCode="AU" term="%22Munir+KM%22">Munir KM</searchLink>; Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Peng+CC%22">Peng CC</searchLink>; Division of Endocrinology and Metabolism, Department of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Loh+CH%22">Loh CH</searchLink>; School of Medicine, Tzu Chi University, Hualien, Taiwan; Center for Aging and Health, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+HK%22">Huang HK</searchLink>; School of Medicine, Tzu Chi University, Hualien, Taiwan; Center for Clinical Epidemiology and Biostatistics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan; Department of Family Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan. Electronic address: drhkhuang@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%228508335%22">Diabetes research and clinical practice</searchLink> [Diabetes Res Clin Pract] 2025 Nov; Vol. 229, pp. 112914. <i>Date of Electronic Publication: </i>2025 Sep 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Scientific+Publishers%22">Elsevier Scientific Publishers </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>8508335 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-8227 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201688227%22">01688227 </searchLink><i>NLM ISO Abbreviation: </i>Diabetes Res Clin Pract <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.diabres.2025.112914
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      – Code: eng
        Text: English
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      – TitleFull: Association of SGLT2 inhibitors and GLP-1 receptor agonists with the risk of Parkinson's disease in patients with type 2 diabetes: A propensity score-matched cohort study with meta-analysis.
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            – D: 01
              M: 11
              Text: 2025 Nov
              Type: published
              Y: 2025
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