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FAK modulates glioblastoma stem cell energetics via regulation of glycolysis and glutamine oxidation.

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Title: FAK modulates glioblastoma stem cell energetics via regulation of glycolysis and glutamine oxidation.
Authors: Masalmeh RHA; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK., Dawson JC; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK., Garcia VA; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK.; Department of Physiology and Pharmacology, School of Medicine, University of Cantabria and Instituto de Investigacion Valdecilla (IDIVAL), 39011 Santander, Spain., Muir MT; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK., Carter RN; UK Dementia Research Institute, Chancellor's Building, University of Edinburgh, 49 Little France Crescent, Edinburgh EH16 4SB, UK., Hardingham GE; UK Dementia Research Institute, Chancellor's Building, University of Edinburgh, 49 Little France Crescent, Edinburgh EH16 4SB, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh EH8 9XF, UK.; Centre for Discovery Brain Sciences, Hugh Robson Building, University of Edinburgh, Edinburgh EH8 9XD, UK., Davies C; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK., Graham R; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK., von Kriegsheim A; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK., Marques J; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK., Pednekar C; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK., Pollard SM; Centre for Regenerative Medicine, Institute for Regeneration and Repair, University of Edinburgh, 5 Little France Drive, Edinburgh EH16 4UU, UK., Carragher NO; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK., Brunton VG; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK., Frame MC; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK.
Source: Disease models & mechanisms [Dis Model Mech] 2025 Nov 01; Vol. 18 (11). Date of Electronic Publication: 2025 Nov 28.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Company of Biologists Ltd Country of Publication: England NLM ID: 101483332 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1754-8411 (Electronic) Linking ISSN: 17548403 NLM ISO Abbreviation: Dis Model Mech Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: FAK modulates glioblastoma stem cell energetics via regulation of glycolysis and glutamine oxidation.
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  Data: <searchLink fieldCode="AU" term="%22Masalmeh+RHA%22">Masalmeh RHA</searchLink>; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Dawson+JC%22">Dawson JC</searchLink>; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Garcia+VA%22">Garcia VA</searchLink>; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK.; Department of Physiology and Pharmacology, School of Medicine, University of Cantabria and Instituto de Investigacion Valdecilla (IDIVAL), 39011 Santander, Spain.<br /><searchLink fieldCode="AU" term="%22Muir+MT%22">Muir MT</searchLink>; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Carter+RN%22">Carter RN</searchLink>; UK Dementia Research Institute, Chancellor's Building, University of Edinburgh, 49 Little France Crescent, Edinburgh EH16 4SB, UK.<br /><searchLink fieldCode="AU" term="%22Hardingham+GE%22">Hardingham GE</searchLink>; UK Dementia Research Institute, Chancellor's Building, University of Edinburgh, 49 Little France Crescent, Edinburgh EH16 4SB, UK.; Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh EH8 9XF, UK.; Centre for Discovery Brain Sciences, Hugh Robson Building, University of Edinburgh, Edinburgh EH8 9XD, UK.<br /><searchLink fieldCode="AU" term="%22Davies+C%22">Davies C</searchLink>; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Graham+R%22">Graham R</searchLink>; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22von+Kriegsheim+A%22">von Kriegsheim A</searchLink>; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Marques+J%22">Marques J</searchLink>; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Pednekar+C%22">Pednekar C</searchLink>; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Pollard+SM%22">Pollard SM</searchLink>; Centre for Regenerative Medicine, Institute for Regeneration and Repair, University of Edinburgh, 5 Little France Drive, Edinburgh EH16 4UU, UK.<br /><searchLink fieldCode="AU" term="%22Carragher+NO%22">Carragher NO</searchLink>; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Brunton+VG%22">Brunton VG</searchLink>; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK.<br /><searchLink fieldCode="AU" term="%22Frame+MC%22">Frame MC</searchLink>; Cancer Research UK Scotland Centre (Edinburgh), Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XU, UK.
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  Data: <searchLink fieldCode="JN" term="%22101483332%22">Disease models & mechanisms</searchLink> [Dis Model Mech] 2025 Nov 01; Vol. 18 (11). <i>Date of Electronic Publication: </i>2025 Nov 28.
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        Value: 10.1242/dmm.052634
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        Text: English
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              Text: 2025 Nov 01
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