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MarkVCID2 Consortium for Clinical Validation of Biomarkers of Cerebral Small Vessel Disease: Validation Framework and Baseline Characteristics.

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Title: MarkVCID2 Consortium for Clinical Validation of Biomarkers of Cerebral Small Vessel Disease: Validation Framework and Baseline Characteristics.
Authors: Greenberg SM; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA., Albert MS; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., An H; Mallinckrodt Institute of Radiology, Washington University in St Louis School of Medicine, St. Louis, MO, USA., Arfanakis K; Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL, USA.; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.; Department of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, IL, USA., Evia AM; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA., Caprihan A; The Mind Research Network, Albuquerque, NM, USA., Ford AL; Mallinckrodt Institute of Radiology, Washington University in St Louis School of Medicine, St. Louis, MO, USA.; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Fornage M; Brown Foundation Institute of Molecular Medicine, McGovern Medical School and Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Day GS; Department of Neurology, Mayo Clinic in Florida, Jacksonville, FL, USA., Hinman JD; David Geffen School of Medicine, Department of Neurology, University of California, Los Angeles, Los Angeles, CA, USA., Jicha GA; Sanders-Brown Center on Aging, University of Kentucky College of Medicine, Lexington, KY, USA., Kashani AH; Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD, USA., Kramer JH; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Lachner C; Department of Neurology, Mayo Clinic in Florida, Jacksonville, FL, USA.; Department of Psychiatry and Psychology, Mayo Clinic, Jacksonville, FL, USA., Lee JM; Mallinckrodt Institute of Radiology, Washington University in St Louis School of Medicine, St. Louis, MO, USA.; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.; Department of Biomedical Engineering, Washington University in Saint Louis, St. Louis, MO, USA., Liu P; Department of Diagnostic Radiology & Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Lu H; Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; F.M. Kirby Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, USA., Maillard P; Department of Neurology, University of California, Davis, Davis, CA, USA., Petersen RC; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, Epidemiology, and Health Systems and Population, University of Washington, Seattle, WA, USA., Ringman JM; Department of Neurology, Alzheimer's Disease Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Rosenberg GA; Center for Memory and Aging, University of New Mexico Health Sciences Center, Albuquerque, NM, USA., Satizabal CL; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health San Antonio, San Antonio, TX, USA.; Department of Population Health Sciences, UT Health San Antonio, San Antonio, TX, USA., Savitz SI; Institute for Stroke and Cerebrovascular Disease, The University of Texas Health Science Center, Houston, TX, USA., Schneider JA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA., Seshadri S; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health San Antonio, San Antonio, TX, USA., Vemuri P; Department of Radiology, Mayo Clinic, Rochester, MN, USA., Wang DJJ; Department of Neurology, Alzheimer's Disease Research Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Wilcock DM; Center for Neurodegenerative Disorders, IUSM/IUH Neuroscience Institute & Stark Neuroscience Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA., Windham BG; Department of Medicine, The MIND Center, University of Mississippi Medical Center, Jackson, MS, USA., Zhang R; Department of Neurology, UT Southwestern Medical Center, Dallas, TX, USA., Tuozzo C; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA., Singh H; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA., Moy S; Department of Radiology, Massachusetts General Hospital, Boston, MA, USA., Okey-Ewurum V; Neurological Clinical Research Institute, Massachusetts General Hospital, Boston, MA, USA., Page CB; Duke Clinical Research Institute, Durham, NC, USA., Mulder H; Duke Clinical Research Institute, Durham, NC, USA., Kivisäkk P; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA., Blacker D; Department of Psychiatry, Mass. General Hospital/Harvard Medical School; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Mazina L; Neurological Clinical Research Institute, Massachusetts General Hospital, Boston, MA, USA., Helmer KG; Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.; Department of Radiology, Harvard Medical School, Boston, MA, USA., Schwab K; Department of Neurology, Massachusetts General Hospital, Boston, MA, USA., Wruck LM; Duke Clinical Research Institute, Durham, NC, USA.; Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA., Corriveau RA; Department of Neuroscience, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
Corporate Authors: MarkVCID2 Consortium
Source: Annals of neurology [Ann Neurol] 2026 Feb; Vol. 99 (2), pp. 449-458. Date of Electronic Publication: 2025 Sep 22.
Publication Type: Journal Article; Validation Study; Multicenter Study; Research Support, N.I.H., Extramural
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7707449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8249 (Electronic) Linking ISSN: 03645134 NLM ISO Abbreviation: Ann Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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