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Antinociceptive, anti-inflammatory, and antiophidic potential of Punica granatum leaves extract and fraction: an in vitro and in vivo evaluation.

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Title: Antinociceptive, anti-inflammatory, and antiophidic potential of Punica granatum leaves extract and fraction: an in vitro and in vivo evaluation.
Authors: Machado JCB; Graduate Program in Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil., da Silva JC; Graduate Program in Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil., Costa WK; Natural Products Laboratory, Department of Biochemistry, Federal University of Pernambuco, Recife, PE, Brazil., da Silva MV; Natural Products Laboratory, Department of Biochemistry, Federal University of Pernambuco, Recife, PE, Brazil., de Oliveria AM; Pharmacy Department, Federal University of Rio Grande do Norte, Natal, RN, Brazil., Daniele-Silva A; Pharmacy Department, Federal University of Rio Grande do Norte, Natal, RN, Brazil., Parente AMES; Pharmacy Department, Federal University of Rio Grande do Norte, Natal, RN, Brazil., de Sousa Ferreira S; Pharmacy Department, Federal University of Rio Grande do Norte, Natal, RN, Brazil., da Silva DP; Pharmacy Department, Federal University of Rio Grande do Norte, Natal, RN, Brazil., Torres-Rêgo M; Pharmacy Department, Federal University of Rio Grande do Norte, Natal, RN, Brazil.; Graduate Program of Chemistry, Chemistry Institute, Federal University of Rio Grande do Norte, Natal, RN, Brazil., Cavalcanti FF; Pharmacy Department, Federal University of Rio Grande do Norte, Natal, RN, Brazil.; Graduate Program of Chemistry, Chemistry Institute, Federal University of Rio Grande do Norte, Natal, RN, Brazil., de Freitas Fernandes-Pedrosa M; Pharmacy Department, Federal University of Rio Grande do Norte, Natal, RN, Brazil., Ferreira MRA; Graduate Program in Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil.; Department of Biomedical Engineering, Federal University of Pernambuco, Recife, PE, Brazil., Soares LAL; Graduate Program in Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil. luiz.albertosoares@ufpe.br.
Source: Inflammopharmacology [Inflammopharmacology] 2025 Oct; Vol. 33 (10), pp. 6057-6074. Date of Electronic Publication: 2025 Sep 23.
Publication Type: Journal Article
Journal Info: Publisher: Birkhäuser Country of Publication: Switzerland NLM ID: 9112626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1568-5608 (Electronic) Linking ISSN: 09254692 NLM ISO Abbreviation: Inflammopharmacology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Antinociceptive, anti-inflammatory, and antiophidic potential of Punica granatum leaves extract and fraction: an in vitro and in vivo evaluation.
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  Data: <searchLink fieldCode="AU" term="%22Machado+JCB%22">Machado JCB</searchLink>; Graduate Program in Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+JC%22">da Silva JC</searchLink>; Graduate Program in Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil.<br /><searchLink fieldCode="AU" term="%22Costa+WK%22">Costa WK</searchLink>; Natural Products Laboratory, Department of Biochemistry, Federal University of Pernambuco, Recife, PE, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+MV%22">da Silva MV</searchLink>; Natural Products Laboratory, Department of Biochemistry, Federal University of Pernambuco, Recife, PE, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Oliveria+AM%22">de Oliveria AM</searchLink>; Pharmacy Department, Federal University of Rio Grande do Norte, Natal, RN, Brazil.<br /><searchLink fieldCode="AU" term="%22Daniele-Silva+A%22">Daniele-Silva A</searchLink>; Pharmacy Department, Federal University of Rio Grande do Norte, Natal, RN, Brazil.<br /><searchLink fieldCode="AU" term="%22Parente+AMES%22">Parente AMES</searchLink>; Pharmacy Department, Federal University of Rio Grande do Norte, Natal, RN, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Sousa+Ferreira+S%22">de Sousa Ferreira S</searchLink>; Pharmacy Department, Federal University of Rio Grande do Norte, Natal, RN, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+DP%22">da Silva DP</searchLink>; Pharmacy Department, Federal University of Rio Grande do Norte, Natal, RN, Brazil.<br /><searchLink fieldCode="AU" term="%22Torres-Rêgo+M%22">Torres-Rêgo M</searchLink>; Pharmacy Department, Federal University of Rio Grande do Norte, Natal, RN, Brazil.; Graduate Program of Chemistry, Chemistry Institute, Federal University of Rio Grande do Norte, Natal, RN, Brazil.<br /><searchLink fieldCode="AU" term="%22Cavalcanti+FF%22">Cavalcanti FF</searchLink>; Pharmacy Department, Federal University of Rio Grande do Norte, Natal, RN, Brazil.; Graduate Program of Chemistry, Chemistry Institute, Federal University of Rio Grande do Norte, Natal, RN, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Freitas+Fernandes-Pedrosa+M%22">de Freitas Fernandes-Pedrosa M</searchLink>; Pharmacy Department, Federal University of Rio Grande do Norte, Natal, RN, Brazil.<br /><searchLink fieldCode="AU" term="%22Ferreira+MRA%22">Ferreira MRA</searchLink>; Graduate Program in Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil.; Department of Biomedical Engineering, Federal University of Pernambuco, Recife, PE, Brazil.<br /><searchLink fieldCode="AU" term="%22Soares+LAL%22">Soares LAL</searchLink>; Graduate Program in Pharmaceutical Sciences, Federal University of Pernambuco, Recife, PE, Brazil. luiz.albertosoares@ufpe.br.
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  Data: <searchLink fieldCode="JN" term="%229112626%22">Inflammopharmacology</searchLink> [Inflammopharmacology] 2025 Oct; Vol. 33 (10), pp. 6057-6074. <i>Date of Electronic Publication: </i>2025 Sep 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Birkhäuser%22">Birkhäuser </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>9112626 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1568-5608 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209254692%22">09254692 </searchLink><i>NLM ISO Abbreviation: </i>Inflammopharmacology <i>Subsets: </i>MEDLINE
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